Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT05903521 · ClinicalTrials.gov registry record

BAriatric Surgery Induced Chromosomal Change

A clinical trial, sponsored by The Cleveland Clinic.

Terminated
Registry status
120
Enrollment target

NCT05903521: Clinical Trial study, sponsored by The Cleveland Clinic.

NCT05903521 is a clinical trial that was terminated before completion, run by The Cleveland Clinic. The registered enrollment target is 120 participants. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT05903521 was terminated before completion, sponsored by The Cleveland Clinic.

TERMINATED
Registry status
120 participants
Enrollment target

Study Summary

The purpose of this study is to better understand the impact of weight-loss surgery on telomere length. Telomeres are a key marker of biological aging of cells. Telomere shortening is a natural process of aging. Several pathologies and lifestyles are associated with premature telomere shortening, such as obesity, diabetes mellitus or sedentary lifestyle. New evidence supports that telomere shortening can be partially reversed by lifestyle changes such as healthy diet, reduced stress, or increased physical activity.

Primary Outcome

Difference in terms of telomere length between patients with obesity class II or more (Body Mass Index \[BMI\] ≥ 35kg/m2) and patients after metabolic and bariatric surgery.

Trial Details

FieldValue
Enrollment Target 120 participants
Start Date 2023-06-12
Est. Completion 2025-01-20
The Cleveland Clinic

688 total trials

Why NCT05903521 stopped before completion

NCT05903521 is an observational study that tracks outcomes without assigning an intervention. The registered 120 participants enrollment target is mid-sized for trials with a published cap.

The record links to 0 conditions, and to 0 interventions.

NCT05903521 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT05903521 about?

NCT05903521 is a clinical study titled "BAriatric Surgery Induced Chromosomal Change". The purpose of this study is to better understand the impact of weight-loss surgery on telomere length. Telomeres are a key marker of biological aging of cells. Telomere shortening is a natural process of aging. Several pathologies and lifestyles are associated with premature telomere shortening, su...

What is the current status of trial NCT05903521?

This trial is currently terminated. The enrollment target is 120 participants. The study started on 2023-06-12. Estimated completion is 2025-01-20.

Who is sponsoring clinical trial NCT05903521?

This trial is sponsored by The Cleveland Clinic, which has 688 total clinical trials registered on ClinicalTrials.gov.

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT01174108 · 120 participants · Phase 2

    Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused With a Reduced Dose of Non-Mobilized Donor T-cells

  • NCT01627301 · 120 participants · NA

    Sympathetic Overactivity in Post-traumatic Stress Disorder

  • NCT02025023 · 120 participants · Phase 3

    Local 5-Fluorouracil Injection for the Treatment of Chalazia: A Prospective, Comparative Study

  • NCT02128906 · 120 participants · Phase 2

    Radiotherapy With Cisplatin vs. Docetaxel-cetuximab in HNSCC: ERCC1 Biomarker Enrichment and Interaction Design

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT05903521, the US trial registry maintained by the National Library of Medicine. NCT05903521 (mid enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.