The Cleveland Clinic
Open enrollment across a mixed-phase pipeline
According to ClinicalTrials.gov-derived indexes, The Cleveland Clinic sits in the top decile of US sponsors by registered trial count (#50 of 15,742 sponsors by registered trial count).
The Cleveland Clinic: 688 sponsored US clinical trials, 99 recruiting.
The Cleveland Clinic sponsors 688 registered US clinical trials on ClinicalTrials.gov, 99 of them currently recruiting, and 437 completed. 81 of these trials are in Phase 3-4 (later-stage) and 76 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Atrial Fibrillation, with 9 trials.
Top-decile sponsor footprint
The Cleveland Clinic ranks in the top decile of sponsors by registered trial count (#50 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Trial completion reliability score
437 of 539 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (81.1%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.
Open and recent trials
688 total, page 10 of 14
Low Fat Vegan or American Heart Association Diets & Cardiovascular Risk in Obese 9-18 y.o. With Elevated Cholesterol
NCT01817491
Trancutaneous Monitoring to Avoid Hypercapnea During Complex Catheter Ablations
NCT01815034
Pain Control After Cardiac Surgery Using Intravenous Acetaminophen
NCT01822821
Bexarotene Amyloid Treatment for Alzheimer's Disease
NCT01782742
Stress Free Now, a Mind-body Reduction Program for Nurses
NCT01796054
Comparison of Glenoid Component Position Using Intelligent Reusable Instrument (IRI) vs Standard Surgical Instruments
NCT01801241
Evaluation of Electrical Nerve Stimulation (TENS) Therapy for Pain Relief Following Total Knee Arthroplasty (TKA)
NCT01641471
PAHTCH Pulmonary Arterial Hypertension Treatment With Carvedilol for Heart Failure (Carvedilol)
NCT01586156
Supplemental Oxygen in Colorectal Surgery: A Quality Improvement Project
NCT01777568
Vapocoolant (Pain Ease Medium Stream) for Intravenous Lines in Emergency Department Patients
NCT01670487
Methionine Metabolism in Parenterally Fed Pediatric Sepsis
NCT01891682
Acupressure for Pain Management and Fatigue Relief in Gulf War Veterans
NCT02075489
Expiratory Muscle Conditioning in Multiple Sclerosis Using Magnetic Stimulation
NCT01758224
Heart-Brain Retraining for Stroke Rehabilitation
NCT02076776
Serum Free Fatty Acid Metabolite Biomarkers of Lung Cancer
NCT01692951
LASIK Flap Thickness and Visual Outcomes Using the WaveLight FS200 Femtosecond Laser
NCT02060461
Optical Coherence Tomography in Multiple Sclerosis Patients
NCT01774123
The Effects of Continuous Transversus Abdominis Plane (TAP) Catheters on Postoperative Pain After Renal Transplantation
NCT01679106
Nicotine Gum Recovery After Colorectal Surgery
NCT01662115
Mechanism and Treatment of Sympathetically Maintained Pain
NCT01813149
Ozurdex for Diabetic Macular Edema Treated With Pars Plana vitrEctomy and Membrane RemovAl (OPERA Study)
NCT01613716
Real-time Ultrasound-guided Paramedian Epidural Access: Evaluation of a Novel In-plane Transverse View Technique
NCT01686243
FRESH Study (Fitness, Relaxation and Eating to Stay Healthy)
NCT01636258
Novel Device to Assess Endotracheal Tube Migration
NCT01697215
A Real-Time Ultrasound Guided Approach For Spinal Anesthesia
NCT01570491
Laparoscopy vs. Robotic Surgery for Endometriosis (LAROSE): a Prospective Randomized Controlled Trial
NCT01556204
Quantitative Heat Loss With Laminar Air Flow
NCT01564212
Navigating the Challenges of Chronic Kidney Disease
NCT01792661
Bile and Bile Duct/Pancreatic Duct Brushings Database for Patients With Pancreato-biliary Stricture
NCT01565460
For Cause Prostate Biopsy in REDUCE Population Trial
NCT01529086
Vitamin D Replacement in Nonalcoholic Fatty Liver Disease
NCT03084328
Influence of Sleep Apnea on Risk of Atrial Fibrillation
NCT02576587
Short Term Outcomes of Heavy-weight Versus Medium-weight Synthetic Mesh
NCT06409091
Oral Iron Supplementation in Pulmonary Hypertension
NCT01446848
Cost of Care for Juvenile Idiopathic Arthritis
NCT01469897
Methionine Metabolism in Enterally Fed Pediatric Sepsis
NCT01889264
The Effect of Systemic or Perineural Dexamethasone on the Duration of Interscalene Nerve Blocks With Ropivacaine
NCT01495624
An Efficacy and Safety Trial of Intranasal Ketorolac in Emergency Department Patients for the Treatment of Acute Pain
NCT01471639
Improving Spinal Cord Injury Rehabilitation Interventions by Retraining the Brain With Stimulation
NCT01539109
Differentiating Unipolar and Bipolar Depression in Young Adults Using fMRI
NCT01811147
Standard Medication Reconciliation Protocol in the Primary Care Office-based Setting
NCT01577602
Effectiveness and Adherence to an Online Sleep Program
NCT01440777
ECG Leadwires: Disposable Versus Cleaned, Reusable
NCT01411553
Value of 25 mcg Cortrosyn Stimulation Test
NCT01428336
Combination Therapy With 5-Fluorouracil and Photodynamic Therapy in Post-transplant Premalignant Skin Disease
NCT01525329
PIONEER: Intraoperative and Perioperative OCT Study
NCT02423161
Volatile Anesthetic Choice and Duration of Hospitalization: A Quality Improvement and Cost-control Project
NCT01379664
Evaluation of Multiscore Feedback in Professionalism for Anesthesia
NCT01522560
A Comparison of Remifentanil and Dexmedetomidine for Craniotomy Perioperative Hemodynamics and Postoperative Pain
NCT01269918
Brain Stimulation-aided Stroke Rehabilitation: Neural Mechanisms of Recovery
NCT01539096
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 38 |
| Phase 2 | 38 |
| Phase 3 | 22 |
| Phase 4 | 59 |
Therapeutic Areas
What is open in the The Cleveland Clinic pipeline
99 recruiting of 688 indexed (14% open); 437 completed (64%).
Phase mix: 81 late (III/IV) vs 76 early (I/II) (balanced across stages).
Top condition: Atrial Fibrillation (9 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
The Cleveland Clinic: open-pipeline peers nationwide
Peers matched on 688 registered trials and 14% open enrollment, not the therapeutic-area sidebar.
The Cleveland Clinic sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.
Sponsors near 688 trials (± recruiting share)
- Vanderbilt University Medical Center · 677 trials · 19% recruiting
- Weill Medical College of Cornell University · 701 trials · 18% recruiting
- Icahn School of Medicine at Mount Sinai · 708 trials · 23% recruiting
- Sanofi · 713 trials · 10% recruiting
Sponsors near 14% open enrollment (± trial volume)
- Dana-Farber Cancer Institute · 14% recruiting · 781 trials
- ModernaTX · 14% recruiting · 90 trials
- Masonic Cancer Center, University of Minnesota · 14% recruiting · 249 trials
- Academic and Community Cancer Research United · 14% recruiting · 42 trials
Related
What to do with this The Cleveland Clinic page
688 registered trials is a research-attention snapshot, not an endorsement of The Cleveland Clinic or any single study.
- 99 of The Cleveland Clinic's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
- Atrial Fibrillation is the condition The Cleveland Clinic studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Atrial Fibrillation trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. The Cleveland Clinic pipeline card: 688 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.