The Cleveland Clinic
The Cleveland Clinic sponsors 688 registered US clinical trials on ClinicalTrials.gov, 99 of them currently recruiting, and 437 completed. 81 of these trials are in Phase 3-4 (later-stage) and 76 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Atrial Fibrillation, with 9 trials.
Trial Pipeline
688 total, page 10 of 14
Low Fat Vegan or American Heart Association Diets & Cardiovascular Risk in Obese 9-18 y.o. With Elevated Cholesterol
NCT01817491
Trancutaneous Monitoring to Avoid Hypercapnea During Complex Catheter Ablations
NCT01815034
Pain Control After Cardiac Surgery Using Intravenous Acetaminophen
NCT01822821
Bexarotene Amyloid Treatment for Alzheimer's Disease
NCT01782742
Stress Free Now, a Mind-body Reduction Program for Nurses
NCT01796054
Comparison of Glenoid Component Position Using Intelligent Reusable Instrument (IRI) vs Standard Surgical Instruments
NCT01801241
Evaluation of Electrical Nerve Stimulation (TENS) Therapy for Pain Relief Following Total Knee Arthroplasty (TKA)
NCT01641471
PAHTCH Pulmonary Arterial Hypertension Treatment With Carvedilol for Heart Failure (Carvedilol)
NCT01586156
Supplemental Oxygen in Colorectal Surgery: A Quality Improvement Project
NCT01777568
Vapocoolant (Pain Ease Medium Stream) for Intravenous Lines in Emergency Department Patients
NCT01670487
Methionine Metabolism in Parenterally Fed Pediatric Sepsis
NCT01891682
Acupressure for Pain Management and Fatigue Relief in Gulf War Veterans
NCT02075489
Expiratory Muscle Conditioning in Multiple Sclerosis Using Magnetic Stimulation
NCT01758224
Heart-Brain Retraining for Stroke Rehabilitation
NCT02076776
Serum Free Fatty Acid Metabolite Biomarkers of Lung Cancer
NCT01692951
LASIK Flap Thickness and Visual Outcomes Using the WaveLight FS200 Femtosecond Laser
NCT02060461
Optical Coherence Tomography in Multiple Sclerosis Patients
NCT01774123
The Effects of Continuous Transversus Abdominis Plane (TAP) Catheters on Postoperative Pain After Renal Transplantation
NCT01679106
Nicotine Gum Recovery After Colorectal Surgery
NCT01662115
Mechanism and Treatment of Sympathetically Maintained Pain
NCT01813149
Ozurdex for Diabetic Macular Edema Treated With Pars Plana vitrEctomy and Membrane RemovAl (OPERA Study)
NCT01613716
Real-time Ultrasound-guided Paramedian Epidural Access: Evaluation of a Novel In-plane Transverse View Technique
NCT01686243
FRESH Study (Fitness, Relaxation and Eating to Stay Healthy)
NCT01636258
Novel Device to Assess Endotracheal Tube Migration
NCT01697215
A Real-Time Ultrasound Guided Approach For Spinal Anesthesia
NCT01570491
Laparoscopy vs. Robotic Surgery for Endometriosis (LAROSE): a Prospective Randomized Controlled Trial
NCT01556204
Quantitative Heat Loss With Laminar Air Flow
NCT01564212
Navigating the Challenges of Chronic Kidney Disease
NCT01792661
Bile and Bile Duct/Pancreatic Duct Brushings Database for Patients With Pancreato-biliary Stricture
NCT01565460
For Cause Prostate Biopsy in REDUCE Population Trial
NCT01529086
Vitamin D Replacement in Nonalcoholic Fatty Liver Disease
NCT03084328
Influence of Sleep Apnea on Risk of Atrial Fibrillation
NCT02576587
Short Term Outcomes of Heavy-weight Versus Medium-weight Synthetic Mesh
NCT06409091
Oral Iron Supplementation in Pulmonary Hypertension
NCT01446848
Cost of Care for Juvenile Idiopathic Arthritis
NCT01469897
Methionine Metabolism in Enterally Fed Pediatric Sepsis
NCT01889264
The Effect of Systemic or Perineural Dexamethasone on the Duration of Interscalene Nerve Blocks With Ropivacaine
NCT01495624
An Efficacy and Safety Trial of Intranasal Ketorolac in Emergency Department Patients for the Treatment of Acute Pain
NCT01471639
Improving Spinal Cord Injury Rehabilitation Interventions by Retraining the Brain With Stimulation
NCT01539109
Differentiating Unipolar and Bipolar Depression in Young Adults Using fMRI
NCT01811147
Standard Medication Reconciliation Protocol in the Primary Care Office-based Setting
NCT01577602
Effectiveness and Adherence to an Online Sleep Program
NCT01440777
ECG Leadwires: Disposable Versus Cleaned, Reusable
NCT01411553
Value of 25 mcg Cortrosyn Stimulation Test
NCT01428336
Combination Therapy With 5-Fluorouracil and Photodynamic Therapy in Post-transplant Premalignant Skin Disease
NCT01525329
PIONEER: Intraoperative and Perioperative OCT Study
NCT02423161
Volatile Anesthetic Choice and Duration of Hospitalization: A Quality Improvement and Cost-control Project
NCT01379664
Evaluation of Multiscore Feedback in Professionalism for Anesthesia
NCT01522560
A Comparison of Remifentanil and Dexmedetomidine for Craniotomy Perioperative Hemodynamics and Postoperative Pain
NCT01269918
Brain Stimulation-aided Stroke Rehabilitation: Neural Mechanisms of Recovery
NCT01539096
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 38 |
| Phase 2 | 38 |
| Phase 3 | 22 |
| Phase 4 | 59 |
Therapeutic Areas
What the Pipeline for The Cleveland Clinic Shows
According to the ClinicalTrials.gov registry, The Cleveland Clinic is linked to 688 US clinical trials across every stage of research activity. Of those, 99 studies are currently recruiting, about 14% of the sponsor's indexed portfolio, and 437 are already marked complete, representing roughly 64% of the total.
The phase mix for The Cleveland Clinic reports 81 late-stage studies (Phase 3 and Phase 4 combined) and 76 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for The Cleveland Clinic is Atrial Fibrillation with 9 linked trials, and 9 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.