The Cleveland Clinic

688 total trials 99 currently recruiting 437 completed

The Cleveland Clinic sponsors 688 registered US clinical trials on ClinicalTrials.gov, 99 of them currently recruiting, and 437 completed. 81 of these trials are in Phase 3-4 (later-stage) and 76 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Atrial Fibrillation, with 9 trials.

Trial Pipeline

688 total, page 10 of 14

COMPLETED NA

Low Fat Vegan or American Heart Association Diets & Cardiovascular Risk in Obese 9-18 y.o. With Elevated Cholesterol

NCT01817491

COMPLETED

Trancutaneous Monitoring to Avoid Hypercapnea During Complex Catheter Ablations

NCT01815034

COMPLETED NA

Pain Control After Cardiac Surgery Using Intravenous Acetaminophen

NCT01822821

COMPLETED Phase 2

Bexarotene Amyloid Treatment for Alzheimer's Disease

NCT01782742

COMPLETED NA

Stress Free Now, a Mind-body Reduction Program for Nurses

NCT01796054

COMPLETED NA

Comparison of Glenoid Component Position Using Intelligent Reusable Instrument (IRI) vs Standard Surgical Instruments

NCT01801241

COMPLETED NA

Evaluation of Electrical Nerve Stimulation (TENS) Therapy for Pain Relief Following Total Knee Arthroplasty (TKA)

NCT01641471

COMPLETED NA

PAHTCH Pulmonary Arterial Hypertension Treatment With Carvedilol for Heart Failure (Carvedilol)

NCT01586156

COMPLETED NA

Supplemental Oxygen in Colorectal Surgery: A Quality Improvement Project

NCT01777568

COMPLETED NA

Vapocoolant (Pain Ease Medium Stream) for Intravenous Lines in Emergency Department Patients

NCT01670487

COMPLETED

Methionine Metabolism in Parenterally Fed Pediatric Sepsis

NCT01891682

COMPLETED NA

Acupressure for Pain Management and Fatigue Relief in Gulf War Veterans

NCT02075489

COMPLETED NA

Expiratory Muscle Conditioning in Multiple Sclerosis Using Magnetic Stimulation

NCT01758224

COMPLETED NA

Heart-Brain Retraining for Stroke Rehabilitation

NCT02076776

COMPLETED

Serum Free Fatty Acid Metabolite Biomarkers of Lung Cancer

NCT01692951

COMPLETED NA

LASIK Flap Thickness and Visual Outcomes Using the WaveLight FS200 Femtosecond Laser

NCT02060461

COMPLETED

Optical Coherence Tomography in Multiple Sclerosis Patients

NCT01774123

TERMINATED NA

The Effects of Continuous Transversus Abdominis Plane (TAP) Catheters on Postoperative Pain After Renal Transplantation

NCT01679106

TERMINATED Phase 4

Nicotine Gum Recovery After Colorectal Surgery

NCT01662115

TERMINATED NA

Mechanism and Treatment of Sympathetically Maintained Pain

NCT01813149

COMPLETED Phase 4

Ozurdex for Diabetic Macular Edema Treated With Pars Plana vitrEctomy and Membrane RemovAl (OPERA Study)

NCT01613716

COMPLETED NA

Real-time Ultrasound-guided Paramedian Epidural Access: Evaluation of a Novel In-plane Transverse View Technique

NCT01686243

COMPLETED NA

FRESH Study (Fitness, Relaxation and Eating to Stay Healthy)

NCT01636258

COMPLETED

Novel Device to Assess Endotracheal Tube Migration

NCT01697215

COMPLETED NA

A Real-Time Ultrasound Guided Approach For Spinal Anesthesia

NCT01570491

COMPLETED NA

Laparoscopy vs. Robotic Surgery for Endometriosis (LAROSE): a Prospective Randomized Controlled Trial

NCT01556204

COMPLETED NA

Quantitative Heat Loss With Laminar Air Flow

NCT01564212

COMPLETED NA

Navigating the Challenges of Chronic Kidney Disease

NCT01792661

COMPLETED

Bile and Bile Duct/Pancreatic Duct Brushings Database for Patients With Pancreato-biliary Stricture

NCT01565460

COMPLETED

For Cause Prostate Biopsy in REDUCE Population Trial

NCT01529086

COMPLETED

Vitamin D Replacement in Nonalcoholic Fatty Liver Disease

NCT03084328

COMPLETED NA

Influence of Sleep Apnea on Risk of Atrial Fibrillation

NCT02576587

COMPLETED

Short Term Outcomes of Heavy-weight Versus Medium-weight Synthetic Mesh

NCT06409091

COMPLETED NA

Oral Iron Supplementation in Pulmonary Hypertension

NCT01446848

COMPLETED

Cost of Care for Juvenile Idiopathic Arthritis

NCT01469897

COMPLETED

Methionine Metabolism in Enterally Fed Pediatric Sepsis

NCT01889264

TERMINATED NA

The Effect of Systemic or Perineural Dexamethasone on the Duration of Interscalene Nerve Blocks With Ropivacaine

NCT01495624

COMPLETED NA

An Efficacy and Safety Trial of Intranasal Ketorolac in Emergency Department Patients for the Treatment of Acute Pain

NCT01471639

COMPLETED NA

Improving Spinal Cord Injury Rehabilitation Interventions by Retraining the Brain With Stimulation

NCT01539109

COMPLETED Phase 4

Differentiating Unipolar and Bipolar Depression in Young Adults Using fMRI

NCT01811147

COMPLETED NA

Standard Medication Reconciliation Protocol in the Primary Care Office-based Setting

NCT01577602

COMPLETED NA

Effectiveness and Adherence to an Online Sleep Program

NCT01440777

COMPLETED NA

ECG Leadwires: Disposable Versus Cleaned, Reusable

NCT01411553

COMPLETED NA

Value of 25 mcg Cortrosyn Stimulation Test

NCT01428336

TERMINATED Phase 3

Combination Therapy With 5-Fluorouracil and Photodynamic Therapy in Post-transplant Premalignant Skin Disease

NCT01525329

COMPLETED

PIONEER: Intraoperative and Perioperative OCT Study

NCT02423161

COMPLETED NA

Volatile Anesthetic Choice and Duration of Hospitalization: A Quality Improvement and Cost-control Project

NCT01379664

COMPLETED NA

Evaluation of Multiscore Feedback in Professionalism for Anesthesia

NCT01522560

COMPLETED NA

A Comparison of Remifentanil and Dexmedetomidine for Craniotomy Perioperative Hemodynamics and Postoperative Pain

NCT01269918

COMPLETED Phase 1

Brain Stimulation-aided Stroke Rehabilitation: Neural Mechanisms of Recovery

NCT01539096

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Phase Distribution

PhaseTrial count
Phase 1 38
Phase 2 38
Phase 3 22
Phase 4 59

What the Pipeline for The Cleveland Clinic Shows

According to the ClinicalTrials.gov registry, The Cleveland Clinic is linked to 688 US clinical trials across every stage of research activity. Of those, 99 studies are currently recruiting, about 14% of the sponsor's indexed portfolio, and 437 are already marked complete, representing roughly 64% of the total.

The phase mix for The Cleveland Clinic reports 81 late-stage studies (Phase 3 and Phase 4 combined) and 76 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for The Cleveland Clinic is Atrial Fibrillation with 9 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.