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NCT01758224 · ClinicalTrials.gov registry record · NA
Expiratory Muscle Conditioning in Multiple Sclerosis Using Magnetic Stimulation
A NA study, sponsored by The Cleveland Clinic.
- Completed
- Registry status
- NA
- Development phase
- 4
- Enrollment target
NCT01758224 is a NA study that has completed, run by The Cleveland Clinic. The registered enrollment target is 4 participants.
The verdict
NCT01758224, a NA study, has completed, sponsored by The Cleveland Clinic.
- COMPLETED
- Registry status
- NA
- Development phase
- 4 participants
- Enrollment target
Study Summary
Multiple sclerosis (MS) is a primary disorder of the central nervous system that may affect motor pathways and cause muscle weakness. Respiratory complications due to respiratory muscle weakness are common in the terminal stages of MS and contribute to mortality in these patients. Respiratory muscle weakness may also impair the performance of coughing and aspiration, pneumonia, or even acute ventilatory failure may ensue. Functional magnetic stimulation (FMS) is a non-invasive method that promotes the contraction of muscles through nerve activation. Over the last few years, the study investigators have demonstrated efficacy of FMS technology for stimulating respiratory muscles in animal models, able-bodied subjects \[3\] and spinal cord injured (SCI) patients \[4\]. In this study, the researchers will investigate the efficacy of using FMS technique for respiratory muscle conditioning in patients with MS. Furthermore, the investigators will also compare expiration related outcomes of FMS technique with resistive expiratory muscle training (REMT) methodology. Hypotheses 1. FMS conditioning of the expiratory muscles can generate significant expiratory flows and pressures in patients with MS. 2. FMS conditioning of expiratory muscles is more effective compared to resistive expiratory muscle training (REMT) in patients with MS.
Interventions
- OTHER Functional Magnetic Stimulation
- OTHER Resistive Expiratory Muscle Training
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 4 participants |
| Start Date | 2012-09 |
| Est. Completion | 2015-09 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01758224
The ClinicalTrials.gov registry entry for NCT01758224 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 4 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is The Cleveland Clinic, which has 688 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Functional Magnetic Stimulation is the first listed.
NCT01758224 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT01758224 about?
NCT01758224 is a clinical study titled "Expiratory Muscle Conditioning in Multiple Sclerosis Using Magnetic Stimulation". Multiple sclerosis (MS) is a primary disorder of the central nervous system that may affect motor pathways and cause muscle weakness. Respiratory complications due to respiratory muscle weakness are common in the terminal stages of MS and contribute to mortality in these patients. Respiratory muscle...
What is the current status of trial NCT01758224?
This trial is currently completed. It is a NA study. The enrollment target is 4 participants. The study started on 2012-09. Estimated completion is 2015-09.
What interventions are being tested in trial NCT01758224?
The interventions under investigation include: Functional Magnetic Stimulation (OTHER), Resistive Expiratory Muscle Training (OTHER).
Who is sponsoring clinical trial NCT01758224?
This trial is sponsored by The Cleveland Clinic, which has 688 total clinical trials registered on ClinicalTrials.gov.
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