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NCT01471639 · ClinicalTrials.gov registry record · NA

An Efficacy and Safety Trial of Intranasal Ketorolac in Emergency Department Patients for the Treatment of Acute Pain

A NA study of Other Acute Pain, sponsored by The Cleveland Clinic.

Completed
Registry status
NA
Development phase
37
Enrollment target
1
Study location

NCT01471639: Completed NA study of Other Acute Pain, sponsored by The Cleveland Clinic.

NCT01471639 is a NA study of Other Acute Pain that has completed, run by The Cleveland Clinic. The registered enrollment target is 37 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01471639, a NA study of Other Acute Pain, has completed, sponsored by The Cleveland Clinic.

COMPLETED
Registry status
NA
Development phase
37 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to determine the effectiveness, the safety, and the tolerability of intranasal ketorolac (Sprix) in relieving acute pain in adults ages 18-65 who come to the ED seeking care. Considering all ED visits, pain is the most common chief complaint. Giving intranasal ketorolac (Sprix) after stomach and dental surgeries has been shown to be safe and effective, but no studies have investigated the use of intranasal ketorolac (Sprix) for the treatment of acute pain in the ED. Ketorolac (Sprix) has several advantages over other drugs commonly given for pain, including opioids. Ketorolac (Sprix) is non-addicting and has fewer side effects than opioids. The administration of ketorolac (Sprix) by other methods, such as IV, intramuscular shot, and oral pill form, has been shown to be safe and effective in treating acute pain. This study is being done to find out if giving ketorolac (Sprix) as a single dose nasal spray will have the same benefit in decreasing patient's pain.

Primary Outcome

Change in numeric rating scale after receiving intranasal ketorolac. 0 (no pain) - 10 (worst possible pain)

Conditions Studied

Interventions

  • DRUG intranasal ketorolac

Study Locations (1)

Ohio

  • Cleveland Clinic - Cleveland

Trial Details

FieldValue
Enrollment Target 37 participants
Start Date 2011-11
Est. Completion 2012-06
Phase NA
The Cleveland Clinic

688 total trials

What the finished NCT01471639 record still lists

NCT01471639 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 37 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).

The record links to 1 condition, with Other Acute Pain appearing as the primary indexed condition, and to 1 intervention - of which intranasal ketorolac is the first listed.

NCT01471639 reports a single indexed study location in Ohio.

Frequently Asked Questions

What is clinical trial NCT01471639 about?

NCT01471639 is a clinical study titled "An Efficacy and Safety Trial of Intranasal Ketorolac in Emergency Department Patients for the Treatment of Acute Pain". The purpose of this study is to determine the effectiveness, the safety, and the tolerability of intranasal ketorolac (Sprix) in relieving acute pain in adults ages 18-65 who come to the ED seeking care. Considering all ED visits, pain is the most common chief complaint. Giving intranasal ketorolac ...

What is the current status of trial NCT01471639?

This trial is currently completed. It is a NA study. The enrollment target is 37 participants. The study started on 2011-11. Estimated completion is 2012-06.

What conditions does trial NCT01471639 study?

This clinical trial studies the following conditions: Other Acute Pain.

What interventions are being tested in trial NCT01471639?

The interventions under investigation include: intranasal ketorolac (DRUG).

Who is sponsoring clinical trial NCT01471639?

This trial is sponsored by The Cleveland Clinic, which has 688 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01471639 being conducted?

This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

How this trial's enrollment target compares

Where NCT01471639's enrollment target sits among peer trials

37 1540th of 2000 higher than 460 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01471639, the US trial registry maintained by the National Library of Medicine. NCT01471639 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.