The Cleveland Clinic

688 total trials 99 currently recruiting 437 completed

The Cleveland Clinic sponsors 688 registered US clinical trials on ClinicalTrials.gov, 99 of them currently recruiting, and 437 completed. 81 of these trials are in Phase 3-4 (later-stage) and 76 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Atrial Fibrillation, with 9 trials.

Trial Pipeline

688 total, page 9 of 14

COMPLETED Phase 3

Use of 6% Hydroxyethylstarch (130/0.4) in Cardiac Surgical Patients

NCT02192502

COMPLETED Phase 2

The COMBINE Study: The CKD Optimal Management With BInders and NicotinamidE

NCT02258074

COMPLETED NA

Evaluation of 3D Visualization for Total Colectomy

NCT02370056

COMPLETED Phase 1

Pomalidomide in Hereditary Hemorrhagic Telangiectasia and Transfusion-Dependent Vascular Ectasia: a Phase I Study

NCT02287558

COMPLETED

Measure of Frailty in Perioperative Setting

NCT02838511

COMPLETED NA

Effect of the Built Operating Room Environment on Patient Outcome

NCT03037905

TERMINATED NA

T-ABA Group Based Early Intervention For Parents of Children With ASD

NCT02202421

TERMINATED

Incisional Hernia and Adhesion-Related Bowel Obstruction

NCT02116881

COMPLETED Phase 3

Effect of Intravenous Acetaminophen on Postoperative Opioid-related Complications

NCT02156154

COMPLETED

Neurotrophin Expression in Infants as a Predictor of Respiratory and Neurodevelopmental Outcomes

NCT03373539

TERMINATED Phase 2

Establishing the Microcirculatory Effects of Ticagrelor on Tissue Perfusion in Critical Limb Ischemia

NCT02230527

COMPLETED

Residual Gastric Volume in Same Day Versus Split Dose and Evening Before Bowel Preparation

NCT02264249

COMPLETED NA

Comparison of Glenoid Position Using SmartBones

NCT03035318

COMPLETED NA

Chronic Kidney Disease Knowledge and Awareness Among American Indians

NCT02309528

COMPLETED Phase 4

Efficacy of Liposomal Bupivacaine for Prolonged Postoperative Analgesia in Patient Undergoing Breast Reconstruction With Tissue Expander

NCT04278846

COMPLETED

Using Smart Phone Technology in Detecting the Presence of Atrial Fibrillation

NCT02214069

TERMINATED NA

Real Time 3D Imaging and Surrogate Bone Model

NCT02204007

TERMINATED NA

Mediterranean Diet and Protein-Sparing Modified Diet for Metabolic Syndrome in Liver Transplant Recipients

NCT02174783

COMPLETED NA

Evaluation of Wound Management With Negative Pressure Dressing Versus Standard Dressing After Revision Arthroplasty.

NCT02127281

COMPLETED Phase 4

Effects of Donepezil HCL on Task-Activated fMRI Brain Activation in Healthy Older Adults at Genetic Risk for Alzheimer's Disease

NCT02087865

COMPLETED NA

Examining the Efficacy of Mattress Technology in Improving the Sleep Quality of Children With ASD

NCT02739321

TERMINATED NA

Effect of the Temperature Used in Thermal Radiofrequency Ablation

NCT02148003

COMPLETED NA

Randomized Trial of Y Mesh vs Dual Mesh

NCT02156687

COMPLETED NA

Optimal Positioning of Nasopharyngeal Temperature Probes: A Prospective Cohort Study

NCT02042625

COMPLETED Phase 3

Protocols for Painless Photodynamic Therapy (PDT) of Actinic Keratoses

NCT02124733

COMPLETED NA

Use of Time-lapse Morphological Kinetics in the Selection of Blastocysts

NCT02081859

COMPLETED NA

Reducing Post-Op Pain After Sacrospinous Ligament Colpopexy

NCT02037061

COMPLETED NA

Cooled Radiofrequency Ablation vs. Thermal Radiofrequency Ablation

NCT02073292

COMPLETED NA

Silk-Like Bed Linens for Prevention of Unit-Acquired Ulcers

NCT02925741

COMPLETED Early Phase 1

Systemic Normothermia in Intracerebral Hemorrhage (ICH)

NCT02078037

COMPLETED NA

Needle Guidance in Ultrasound Guided Nerve Blocks

NCT02080481

COMPLETED NA

Effects of a Home Based Walking Program Using Rhythmic Auditory Stimulation in Patients With Multiple Sclerosis

NCT02065284

COMPLETED NA

REstrictive Versus LIbEral Fluid Therapy in Major Abdominal Surgery

NCT02073162

COMPLETED

Endothelial Function in Patients With Scleroderma or Cirrhosis With and Without Pulmonary Hypertension

NCT01729611

COMPLETED NA

Impact of Influenza Vaccination in Pregnancy Video Education

NCT02151201

COMPLETED NA

Use of Capnography in EGD and Colonoscopy With Moderate Sedation.

NCT01994785

COMPLETED Phase 2

Cyclosporine in Interstitial Cystitis: Efficacy, Safety and Mechanism of Action

NCT01990898

TERMINATED Phase 2

TRACER RGD-K5 Carotid Plaque Imaging Study

NCT01968226

TERMINATED

Real-Time Instrument for Acetabular Shell Positioning

NCT02006251

COMPLETED NA

Use of Real Time Instrumentation (RTI) in Total Shoulder Arthroplasty

NCT01905241

COMPLETED

Natural History of Cherubism Observational Study

NCT01916772

COMPLETED NA

Interventions to Decrease Anxiety in Patients Undergoing Urodynamic Testing

NCT02168556

COMPLETED

Evaluating the Efficacy and Feasibility of a Novel Wireless ECG Recording System in Monitoring Patients After Atrial Fibrillation Ablation Procedure

NCT01912911

COMPLETED Phase 4

Ancillary Effects of Dexmedetomidine Sedation After Cardiac Surgery

NCT02004613

COMPLETED NA

a Diagnostic SIJ Injection Following a Composite of 3 Diagnostic Tests and a Pain Referral Diagram

NCT01875406

COMPLETED NA

The Cyclical Lower-extremity Exercise for Parkinson's Trial

NCT01636297

TERMINATED Phase 1

Trial of Cooling for Patients With Excel Cryo Cooling System in Intracerebral Hemorrhage (ICH)

NCT01933230

COMPLETED NA

Acupuncture on Cardiac and Autonomic Function in Human Heart Failure

NCT01804816

COMPLETED

Organ Donor Tissue Oxygen Saturation as a Predictor of Number of Organs to Transplant Per Donor

NCT01819116

TERMINATED NA

Vitagel Revision Total Knee Arthroplasty

NCT01923805

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Phase Distribution

PhaseTrial count
Phase 1 38
Phase 2 38
Phase 3 22
Phase 4 59

What the Pipeline for The Cleveland Clinic Shows

According to the ClinicalTrials.gov registry, The Cleveland Clinic is linked to 688 US clinical trials across every stage of research activity. Of those, 99 studies are currently recruiting, about 14% of the sponsor's indexed portfolio, and 437 are already marked complete, representing roughly 64% of the total.

The phase mix for The Cleveland Clinic reports 81 late-stage studies (Phase 3 and Phase 4 combined) and 76 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for The Cleveland Clinic is Atrial Fibrillation with 9 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.