The Cleveland Clinic
The Cleveland Clinic sponsors 688 registered US clinical trials on ClinicalTrials.gov, 99 of them currently recruiting, and 437 completed. 81 of these trials are in Phase 3-4 (later-stage) and 76 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Atrial Fibrillation, with 9 trials.
Trial Pipeline
688 total, page 9 of 14
Use of 6% Hydroxyethylstarch (130/0.4) in Cardiac Surgical Patients
NCT02192502
The COMBINE Study: The CKD Optimal Management With BInders and NicotinamidE
NCT02258074
Evaluation of 3D Visualization for Total Colectomy
NCT02370056
Pomalidomide in Hereditary Hemorrhagic Telangiectasia and Transfusion-Dependent Vascular Ectasia: a Phase I Study
NCT02287558
Measure of Frailty in Perioperative Setting
NCT02838511
Effect of the Built Operating Room Environment on Patient Outcome
NCT03037905
T-ABA Group Based Early Intervention For Parents of Children With ASD
NCT02202421
Incisional Hernia and Adhesion-Related Bowel Obstruction
NCT02116881
Effect of Intravenous Acetaminophen on Postoperative Opioid-related Complications
NCT02156154
Neurotrophin Expression in Infants as a Predictor of Respiratory and Neurodevelopmental Outcomes
NCT03373539
Establishing the Microcirculatory Effects of Ticagrelor on Tissue Perfusion in Critical Limb Ischemia
NCT02230527
Residual Gastric Volume in Same Day Versus Split Dose and Evening Before Bowel Preparation
NCT02264249
Comparison of Glenoid Position Using SmartBones
NCT03035318
Chronic Kidney Disease Knowledge and Awareness Among American Indians
NCT02309528
Efficacy of Liposomal Bupivacaine for Prolonged Postoperative Analgesia in Patient Undergoing Breast Reconstruction With Tissue Expander
NCT04278846
Using Smart Phone Technology in Detecting the Presence of Atrial Fibrillation
NCT02214069
Real Time 3D Imaging and Surrogate Bone Model
NCT02204007
Mediterranean Diet and Protein-Sparing Modified Diet for Metabolic Syndrome in Liver Transplant Recipients
NCT02174783
Evaluation of Wound Management With Negative Pressure Dressing Versus Standard Dressing After Revision Arthroplasty.
NCT02127281
Effects of Donepezil HCL on Task-Activated fMRI Brain Activation in Healthy Older Adults at Genetic Risk for Alzheimer's Disease
NCT02087865
Examining the Efficacy of Mattress Technology in Improving the Sleep Quality of Children With ASD
NCT02739321
Effect of the Temperature Used in Thermal Radiofrequency Ablation
NCT02148003
Randomized Trial of Y Mesh vs Dual Mesh
NCT02156687
Optimal Positioning of Nasopharyngeal Temperature Probes: A Prospective Cohort Study
NCT02042625
Protocols for Painless Photodynamic Therapy (PDT) of Actinic Keratoses
NCT02124733
Use of Time-lapse Morphological Kinetics in the Selection of Blastocysts
NCT02081859
Reducing Post-Op Pain After Sacrospinous Ligament Colpopexy
NCT02037061
Cooled Radiofrequency Ablation vs. Thermal Radiofrequency Ablation
NCT02073292
Silk-Like Bed Linens for Prevention of Unit-Acquired Ulcers
NCT02925741
Systemic Normothermia in Intracerebral Hemorrhage (ICH)
NCT02078037
Needle Guidance in Ultrasound Guided Nerve Blocks
NCT02080481
Effects of a Home Based Walking Program Using Rhythmic Auditory Stimulation in Patients With Multiple Sclerosis
NCT02065284
REstrictive Versus LIbEral Fluid Therapy in Major Abdominal Surgery
NCT02073162
Endothelial Function in Patients With Scleroderma or Cirrhosis With and Without Pulmonary Hypertension
NCT01729611
Impact of Influenza Vaccination in Pregnancy Video Education
NCT02151201
Use of Capnography in EGD and Colonoscopy With Moderate Sedation.
NCT01994785
Cyclosporine in Interstitial Cystitis: Efficacy, Safety and Mechanism of Action
NCT01990898
TRACER RGD-K5 Carotid Plaque Imaging Study
NCT01968226
Real-Time Instrument for Acetabular Shell Positioning
NCT02006251
Use of Real Time Instrumentation (RTI) in Total Shoulder Arthroplasty
NCT01905241
Natural History of Cherubism Observational Study
NCT01916772
Interventions to Decrease Anxiety in Patients Undergoing Urodynamic Testing
NCT02168556
Evaluating the Efficacy and Feasibility of a Novel Wireless ECG Recording System in Monitoring Patients After Atrial Fibrillation Ablation Procedure
NCT01912911
Ancillary Effects of Dexmedetomidine Sedation After Cardiac Surgery
NCT02004613
a Diagnostic SIJ Injection Following a Composite of 3 Diagnostic Tests and a Pain Referral Diagram
NCT01875406
The Cyclical Lower-extremity Exercise for Parkinson's Trial
NCT01636297
Trial of Cooling for Patients With Excel Cryo Cooling System in Intracerebral Hemorrhage (ICH)
NCT01933230
Acupuncture on Cardiac and Autonomic Function in Human Heart Failure
NCT01804816
Organ Donor Tissue Oxygen Saturation as a Predictor of Number of Organs to Transplant Per Donor
NCT01819116
Vitagel Revision Total Knee Arthroplasty
NCT01923805
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 38 |
| Phase 2 | 38 |
| Phase 3 | 22 |
| Phase 4 | 59 |
Therapeutic Areas
What the Pipeline for The Cleveland Clinic Shows
According to the ClinicalTrials.gov registry, The Cleveland Clinic is linked to 688 US clinical trials across every stage of research activity. Of those, 99 studies are currently recruiting, about 14% of the sponsor's indexed portfolio, and 437 are already marked complete, representing roughly 64% of the total.
The phase mix for The Cleveland Clinic reports 81 late-stage studies (Phase 3 and Phase 4 combined) and 76 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for The Cleveland Clinic is Atrial Fibrillation with 9 linked trials, and 9 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.