St. Jude Children's Research Hospital

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, St. Jude Children's Research Hospital sits in the top decile of US sponsors by registered trial count (#87 of 15,742 sponsors by registered trial count).

410 total trials 90 currently recruiting 227 completed early-phase tilt top decile by trial count

St. Jude Children's Research Hospital: 410 sponsored US clinical trials, 90 recruiting.

St. Jude Children's Research Hospital sponsors 410 registered US clinical trials on ClinicalTrials.gov, 90 of them currently recruiting, and 227 completed. 19 of these trials are in Phase 3-4 (later-stage) and 173 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Sickle Cell Disease, with 17 trials.

Top-decile sponsor footprint

St. Jude Children's Research Hospital ranks in the top decile of sponsors by registered trial count (#87 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 59/100

227 of 259 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (87.6%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

410 total, page 5 of 9

COMPLETED Phase 1

Intravitreal Carboplatin for the Treatment of Participants With Recurrent or Refractory Intraocular Retinoblastoma

NCT02792036

COMPLETED

Analysis of T Cell and Natural Killer (NK) Cell in Relation to Viral Infections in Pediatric Stem Cell Transplant Patients and Donors

NCT02301065

COMPLETED

Understanding Communication in Healthcare to Achieve Trust (U-CHAT)

NCT02846038

COMPLETED

Neurocognitive and Psychosocial Outcomes in Survivors of Childhood Leukemia With Down Syndrome

NCT02859389

COMPLETED

Genetic Study of Families With High Frequency of Hodgkin Lymphoma

NCT02795013

COMPLETED

Social Cognition and Brain Integrity in Survivors of Pediatric Medulloblastoma

NCT02747576

TERMINATED Phase 1

Panobinostat With Fludarabine and Cytarabine for Treatment of Children With Acute Myeloid Leukemia or Myelodysplastic Syndrome

NCT02676323

COMPLETED Phase 1

First-in-Human Study of an Oral Plasmodium Falciparum Plasma Membrane Protein Inhibitor

NCT02661373

COMPLETED

Bereaved Parent Study

NCT02425787

TERMINATED

Medical Treatment Decision Making Using Adaptive Conjoint Analysis

NCT02608307

COMPLETED

iPSC Neurons From Adult Survivors of Childhood Cancer Who Have Persistent Vincristine-Induced Neuropathy

NCT02564484

COMPLETED Phase 2

Influenza Virus Vaccine Plus Vitamin A and D Supplements for Prevention of Respiratory Virus Infections in Children

NCT02649192

TERMINATED Phase 2

Selinexor in Combination With Fludarabine and Cytarabine in Patients With Refractory or Relapsed Acute Myeloid Leukemia

NCT03071276

COMPLETED

Epidemiology of Diarrheal Diseases in Pediatric Oncology Patients

NCT02464098

COMPLETED NA

Impact of Resistance Training-Protein Supplementation on Lean Muscle Mass in Childhood Cancer Survivors

NCT02501460

COMPLETED NA

Light Therapy to Increase Energy in Adolescents and Young Adults Newly Diagnosed With Solid Tumors: A Pilot Study

NCT02429063

COMPLETED NA

Diffusion Weighted Magnetic Resonance in Imaging Younger Patients With Newly Diagnosed Bone or Soft Tissue Sarcomas

NCT02415816

COMPLETED

Functional Outcomes Following Hip Core Decompression in Younger Participants With Osteonecrosis

NCT02458937

COMPLETED

Assessing Blood Pressure Remotely in Childhood Cancer Survivors

NCT02476162

TERMINATED NA

Yoga to Alleviate Fatigue, Anxiety and Pain in Adolescents During Treatment for Lymphoma or Leukemia

NCT02473523

TERMINATED Phase 2

Microtransplantation to Treat Refractory or Relapsed Hematologic Malignancies in Younger Patients

NCT02433483

TERMINATED Phase 2

Bortezomib and Vorinostat in Younger Patients With Refractory or Relapsed MLL Rearranged Hematologic Malignancies

NCT02419755

COMPLETED Phase 1

Crenolanib in Combination With Sorafenib in Patients With Refractory or Relapsed Hematologic Malignancies

NCT02270788

COMPLETED

A Pilot Study of Influenza Viruses Isolated From Immunocompromised Children and Adolescents

NCT02352389

COMPLETED Phase 1

Talazoparib Plus Irinotecan With or Without Temozolomide in Children With Refractory or Recurrent Solid Malignancies

NCT02392793

COMPLETED

Lactation Outcomes Among Survivors of Pediatric Cancer

NCT02399956

COMPLETED NA

Treatment for Executive Dysfunction in Adult Survivors of Childhood Acute Lymphoblastic Leukemia

NCT02336282

COMPLETED

Feasibility of Generating Pluripotent Stem Cells From Patients With Familial Retinoblastoma

NCT02193724

COMPLETED NA

Theraworx Bath Wipes Versus Standard Bath Wipes in the Reduction of Vancomycin-Resistant Enterococci

NCT02241005

COMPLETED Phase 1

A Pilot Study of Immunotherapy Including Haploidentical NK Cell Infusion Following CD133+ Positively-Selected Autologous Hematopoietic Stem Cells in Children With High Risk Solid Tumors or Lymphomas

NCT02130869

COMPLETED

A New Reagent Assay Examining Natural Parvovirus B19 Infection in Sickle Cell Disease

NCT02261480

TERMINATED Phase 2

Repeat Transplantation for Relapsed or Refractory Hematologic Malignancies Following Prior Transplantation

NCT02259348

COMPLETED

Working Memory and School Readiness in Preschool-Aged Children With Sickle Cell Disease

NCT02227472

COMPLETED Phase 1

Selinexor With Fludarabine and Cytarabine for Treatment of Refractory or Relapsed Leukemia or Myelodysplastic Syndrome

NCT02212561

COMPLETED

Pretreatment Anti-Therapeutic Antibodies (PATA) in Patients Treated With hu14.18K322A Antibody

NCT02159443

TERMINATED Phase 2

Combined T Cell Depleted Haploidentical Peripheral Blood Stem Cell and Unrelated Umbilical Cord Blood Transplantation in Patients With Hematologic Malignancies Using a Total Lymphoid Irradiation Based Preparative Regimen

NCT02199041

COMPLETED

The Good Patient Study

NCT02199548

COMPLETED

Incentives to Promote Medication Adherence Among HIV-Infected Youth

NCT02206906

COMPLETED

Medication Adherence in Youth With Sickle Cell Disease (SCD)

NCT02143076

COMPLETED NA

Medication Adherence in Human Immunodeficiency Virus (HIV)

NCT02119390

COMPLETED

A Qualitative Case Study of the Experiences of Children With Cancer as They Learn About Their Diagnosis and Treatment

NCT02041689

COMPLETED

Vascular Assessment in Adult Survivors of Childhood Cancer

NCT02010190

COMPLETED

Transfusional Iron Overload Among Leukemia Survivors

NCT01965171

COMPLETED Phase 2

Pain Management in Children and Young Adults With Sickle Cell Disease

NCT01954927

COMPLETED

Evaluation of Nocturnal Enuresis and Barriers to Treatment Among Pediatric Patients With Sickle Cell Disease

NCT01959958

COMPLETED Phase 1

Bendamustine Hydrochloride, Clofarabine, and Etoposide in Treating Younger Patients With Relapsed or Refractory Hematologic Malignancies

NCT01900509

COMPLETED

Evaluating Rewards-Based Adherence and Electronic Medication Monitoring in HIV-Positive Adolescents

NCT01849393

COMPLETED Phase 2

Haploidentical Donor Hematopoietic Progenitor Cell and NK Cell Transplantation for Hematologic Malignancy

NCT01807611

COMPLETED

Brain Integrity in Survivors of Hodgkin Lymphoma Treated With Thoracic Radiation

NCT01820117

COMPLETED Phase 2

Therapy for Pediatric Relapsed or Refractory Precursor B-Cell Acute Lymphoblastic Leukemia and Lymphoma

NCT01700946

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Phase Distribution

PhaseTrial count
Phase 1 87
Phase 2 86
Phase 3 17
Phase 4 2

What is open in the St. Jude Children's Research Hospital pipeline

90 recruiting of 410 indexed (22% open); 227 completed (55%).

Phase mix: 19 late (III/IV) vs 173 early (I/II) (early-phase heavy).

Top condition: Sickle Cell Disease (17 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

St. Jude Children's Research Hospital: open-pipeline peers nationwide

Peers matched on 410 registered trials and 22% open enrollment, not the therapeutic-area sidebar.

St. Jude Children's Research Hospital sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0100200300400500 10%15%20%25%30% Total trials Recruiting share St. Jude Children's Research HospitalTakedaUniversity of Kansas Medical CenterRutgers, The State University of New JerseyCase Comprehensive Cancer CenterNorthwell HealthVanda PharmaceuticalsBoston University Charles River CampusRegeneron Pharmaceuticals
St. Jude Children's Research Hospital sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

St. Jude Children's Research Hospital sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 410 trials (± recruiting share)

Sponsors near 22% open enrollment (± trial volume)

What to do with this St. Jude Children's Research Hospital page

410 registered trials is a research-attention snapshot, not an endorsement of St. Jude Children's Research Hospital or any single study.

  • 90 of St. Jude Children's Research Hospital's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Sickle Cell Disease is the condition St. Jude Children's Research Hospital studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Sickle Cell Disease trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

St. Jude Children's Research Hospital pipeline card: 410 registered trials from official public datasets.Report a data error.