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NCT06819475 · ClinicalTrials.gov registry record · NA
Imaging Skeletal Muscle Mitochondrial OXPHOS Activity In Acute Lymphoblastic Leukemia Survivors
A NA study of Muscle Weakness and Childhood Cancer, sponsored by St. Jude Children's Research Hospital.
- Recruiting
- Registry status
- NA
- Development phase
- 60
- Enrollment target
- 1
- Study location
NCT06819475 is a NA study of Muscle Weakness and Childhood Cancer that is actively recruiting participants, run by St. Jude Children's Research Hospital. The registered enrollment target is 60 participants, below the 73-participant average among 25 other Muscle Weakness trials with a reported enrollment target (18% lower). The trial reports 1 study location across 1 state.
The verdict
NCT06819475, a NA study of Muscle Weakness and Childhood Cancer, is actively recruiting participants, sponsored by St. Jude Children's Research Hospital.
- RECRUITING
- Registry status
- NA
- Development phase
- 60 participants
- Enrollment target
- 1
- Study location
Study Summary
The participants are being asked to take part in this trial, because the participant is a survivor of childhood cancer or agreed to be part of a volunteer group to understand the relation between cancer and cancer treatment and muscle weakness in survivors of Acute Lymphoblastic Leukemia (ALL). ALL is cancer of the blood and bone marrow. Primary Objective • To compare muscle mtOXPHOS activity and satellite cell content among ALL survivors and controls. Secondary Objective * To evaluate the association between muscle mtOXPHOS, muscle satellite cell content and physical performance in ALL survivors. * To evaluate the association of muscle morphology and epigenetics with muscle mtOXPHOS in ALL survivors.
Conditions Studied
Interventions
- OTHER Physical function assessment
- DIAGNOSTIC_TEST Magnetic Resonance Imaging
- DIAGNOSTIC_TEST Magnetic Resonance Spectroscopy
- OTHER Peripheral blood sample
- OTHER Skeletal muscle biopsy
Study Locations (1)
Tennessee
- St. Jude Children's Research Hospital - Memphis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2025-06-02 |
| Est. Completion | 2028-01 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06819475
The ClinicalTrials.gov registry entry for NCT06819475 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 60 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 73-participant average among 25 other Muscle Weakness trials with a reported enrollment target (18% lower). The listed sponsor is St. Jude Children's Research Hospital, which has 410 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Muscle Weakness appearing as the primary indexed condition, and to 5 interventions - of which Physical function assessment is the first listed.
NCT06819475 reports 1 study location spanning 1 distinct geographic area - top geographies include Tennessee.
Frequently Asked Questions
What is clinical trial NCT06819475 about?
NCT06819475 is a clinical study titled "Imaging Skeletal Muscle Mitochondrial OXPHOS Activity In Acute Lymphoblastic Leukemia Survivors". The participants are being asked to take part in this trial, because the participant is a survivor of childhood cancer or agreed to be part of a volunteer group to understand the relation between cancer and cancer treatment and muscle weakness in survivors of Acute Lymphoblastic Leukemia (ALL). ALL ...
What is the current status of trial NCT06819475?
This trial is currently recruiting. It is a NA study. The enrollment target is 60 participants. The study started on 2025-06-02. Estimated completion is 2028-01.
What conditions does trial NCT06819475 study?
This clinical trial studies the following conditions: Muscle Weakness, Childhood Cancer.
What interventions are being tested in trial NCT06819475?
The interventions under investigation include: Physical function assessment (OTHER), Magnetic Resonance Imaging (DIAGNOSTIC_TEST), Magnetic Resonance Spectroscopy (DIAGNOSTIC_TEST), Peripheral blood sample (OTHER), Skeletal muscle biopsy (OTHER).
Who is sponsoring clinical trial NCT06819475?
This trial is sponsored by St. Jude Children's Research Hospital, which has 410 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06819475 being conducted?
This trial has 1 study location across Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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