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NCT06747910 · ClinicalTrials.gov registry record · NA
Assessment of Remote Approaches for Identification of Autonomic Dysfunction Among Survivors of Leukemia and Lymphoma
A NA study of Childhood Cancer, sponsored by St. Jude Children's Research Hospital.
- Recruiting
- Registry status
- NA
- Development phase
- 188
- Enrollment target
- 1
- Study location
NCT06747910: Recruiting NA study of Childhood Cancer, sponsored by St. Jude Children's Research Hospital.
NCT06747910 is a NA study of Childhood Cancer that is actively recruiting participants, run by St. Jude Children's Research Hospital. The registered enrollment target is 188 participants, below the 1,464-participant average among 23 other Childhood Cancer trials with a reported enrollment target (87% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06747910, a NA study of Childhood Cancer, is actively recruiting participants, sponsored by St. Jude Children's Research Hospital.
- RECRUITING
- Registry status
- NA
- Development phase
- 188 participants
- Enrollment target
- 1
- Study location
Study Summary
This study seeks to determine if diagnosing cardiac autonomic dysfunction (AD) can be done remotely with the same accuracy as in-person testing. If so, the identification of AD could happen sooner, facilitating remote studies of the condition and potentially reducing the risk of illness. Childhood cancer survivors, particularly survivors of acute lymphoblastic leukemia (ALL) and Hodgkins's lymphoma (HL), appear to be at increased risk for AD. Primary Objectives: * To determine the sensitivity and specificity of heart rate variability (HRV), measured remotely with biosensor technology (Actigraph LEAP), compared to in-person assessment using the Ewing battery as the reference standard to identify cardiac autonomic dysfunction (AD) among survivors of leukemia and lymphoma. * To determine the sensitivity and specificity of the Composite Autonomic Symptom Scale 31 (COMPASS31) compared to the Ewing battery to identify AD among leukemia and lymphoma survivors.
Primary Outcome
The standard deviation of normal-to-normal heartbeat intervals over a 24-hour period measured in milliseconds
Conditions Studied
Interventions
- OTHER Questionnaire Administration
- OTHER Exercise Intervention - Ewing Battery Assessment
- DEVICE Medical Device Usage and Evaluation
Study Locations (1)
Tennessee
- St. Jude Children's Research Hospital - Memphis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 188 participants |
| Start Date | 2025-02-03 |
| Est. Completion | 2026-06 |
| Phase | NA |
What NCT06747910 shows while recruiting
NCT06747910 is an interventional study that assigns participants to a tested intervention. The registered 188 participants enrollment target is mid-sized for trials with a published cap, below the 1,464-participant average among 23 other Childhood Cancer trials with a reported enrollment target (87% lower).
The record links to 1 condition, with Childhood Cancer appearing as the primary indexed condition, and to 3 interventions - of which Questionnaire Administration is the first listed.
NCT06747910 reports a single indexed study location in Tennessee.
Frequently Asked Questions
What is clinical trial NCT06747910 about?
NCT06747910 is a clinical study titled "Assessment of Remote Approaches for Identification of Autonomic Dysfunction Among Survivors of Leukemia and Lymphoma". This study seeks to determine if diagnosing cardiac autonomic dysfunction (AD) can be done remotely with the same accuracy as in-person testing. If so, the identification of AD could happen sooner, facilitating remote studies of the condition and potentially reducing the risk of illness. Childhood c...
What is the current status of trial NCT06747910?
This trial is currently recruiting. It is a NA study. The enrollment target is 188 participants. The study started on 2025-02-03. Estimated completion is 2026-06.
What conditions does trial NCT06747910 study?
This clinical trial studies the following conditions: Childhood Cancer.
What interventions are being tested in trial NCT06747910?
The interventions under investigation include: Questionnaire Administration (OTHER), Exercise Intervention - Ewing Battery Assessment (OTHER), Medical Device Usage and Evaluation (DEVICE).
Who is sponsoring clinical trial NCT06747910?
This trial is sponsored by St. Jude Children's Research Hospital, which has 410 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06747910 being conducted?
This trial has 1 study location across Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Childhood Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06747910's enrollment target sits among peer trials
188 6th of 23 higher than 17 of 23 other Childhood Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Childhood Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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