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NCT06289673 · ClinicalTrials.gov registry record · Phase 4

Identification of Necessary Information for Treatment Induction in Newly Diagnosed Acute Lymphoblastic Leukemia/Lymphoma

A Phase 4 study of Acute Lymphoblastic Leukemia and Mixed Phenotype Acute Leukemia, sponsored by St. Jude Children's Research Hospital.

Recruiting
Registry status
Phase 4
Development phase
850
Enrollment target
3
Study locations

NCT06289673 is a Phase 4 study of Acute Lymphoblastic Leukemia and Mixed Phenotype Acute Leukemia that is actively recruiting participants, run by St. Jude Children's Research Hospital. The registered enrollment target is 850 participants, above the 376-participant average among 131 other Acute Lymphoblastic Leukemia trials with a reported enrollment target (126% higher). The trial reports 3 study locations across 3 states.

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The verdict

NCT06289673, a Phase 4 study of Acute Lymphoblastic Leukemia and Mixed Phenotype Acute Leukemia, is actively recruiting participants, sponsored by St. Jude Children's Research Hospital.

RECRUITING
Registry status
Phase 4
Development phase
850 participants
Enrollment target
3
Study locations

Study Summary

The goal of this study is to provide sufficient therapy during the time a patients' B-cell Acute Lymphoblastic Leukemia (ALL) or Lymphoblastic Lymphoma (LLy) risk category is being determined. The term "risk" refers to the chance of the ALL or LLy coming back after treatment. Primary Objectives * To provide sufficient therapy to enable testing of newly diagnosed acute lymphoblastic leukemia/lymphoma and mixed phenotype acute leukemia/lymphoma tumor samples to determine eligibility and appropriate risk stratification for SJALL therapeutic studies. * To develop a central database of genomic and clinical findings. Secondary Objectives * To assess event free and overall survival data of patients enrolled on this study.

Interventions

  • DRUG Dexamethasone
  • DRUG Vincristine
  • DRUG Daunorubicin
  • DRUG Methotrexate
  • DRUG Intrathecal triple therapy (methotrexate + hydrocortisone + cytarabine)

Study Locations (3)

California

  • Rady Children's Hospital - San Diego

Oklahoma

  • Saint Francis Children's Hospital - Tulsa

Tennessee

  • St. Jude Children's Research Hospital - Memphis

Trial Details

FieldValue
Enrollment Target 850 participants
Start Date 2024-12-26
Est. Completion 2039-05
Phase Phase 4

What the Registry Record Tells You About NCT06289673

The ClinicalTrials.gov registry entry for NCT06289673 describes a study currently listed as recruiting, categorized as Phase 4. The registered enrollment target is 850 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 376-participant average among 131 other Acute Lymphoblastic Leukemia trials with a reported enrollment target (126% higher). The listed sponsor is St. Jude Children's Research Hospital, which has 410 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Acute Lymphoblastic Leukemia appearing as the primary indexed condition, and to 5 interventions - of which Dexamethasone is the first listed.

NCT06289673 reports 3 study locations spanning 3 distinct geographic areas - top geographies include California, Oklahoma, Tennessee.

Frequently Asked Questions

What is clinical trial NCT06289673 about?

NCT06289673 is a clinical study titled "Identification of Necessary Information for Treatment Induction in Newly Diagnosed Acute Lymphoblastic Leukemia/Lymphoma". The goal of this study is to provide sufficient therapy during the time a patients' B-cell Acute Lymphoblastic Leukemia (ALL) or Lymphoblastic Lymphoma (LLy) risk category is being determined. The term "risk" refers to the chance of the ALL or LLy coming back after treatment. Primary Objectives * ...

What is the current status of trial NCT06289673?

This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 850 participants. The study started on 2024-12-26. Estimated completion is 2039-05.

What conditions does trial NCT06289673 study?

This clinical trial studies the following conditions: Acute Lymphoblastic Leukemia, Mixed Phenotype Acute Leukemia, Lymphoblastic Lymphoma.

What interventions are being tested in trial NCT06289673?

The interventions under investigation include: Dexamethasone (DRUG), Vincristine (DRUG), Daunorubicin (DRUG), Methotrexate (DRUG), Intrathecal triple therapy (methotrexate + hydrocortisone + cytarabine) (DRUG).

Who is sponsoring clinical trial NCT06289673?

This trial is sponsored by St. Jude Children's Research Hospital, which has 410 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06289673 being conducted?

This trial has 3 study locations across California, Oklahoma, Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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