Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT05664113 · ClinicalTrials.gov registry record · Phase 1
Feasibility, Safety, and Potential Efficacy of Fecal Microbiota Transplantation (FMT) for Gastrointestinal Dysfunction in Children Following Hematopoietic Cell Transplant (HCT).
A Phase 1 study of Gastro-Intestinal Disorder, sponsored by St. Jude Children's Research Hospital.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 10
- Enrollment target
- 1
- Study location
NCT05664113: Recruiting Phase 1 study of Gastro-Intestinal Disorder, sponsored by St. Jude Children's Research Hospital.
NCT05664113 is a Phase 1 study of Gastro-Intestinal Disorder that is actively recruiting participants, run by St. Jude Children's Research Hospital. The registered enrollment target is 10 participants, below the 183-participant average among 7 other Gastro-Intestinal Disorder trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05664113, a Phase 1 study of Gastro-Intestinal Disorder, is actively recruiting participants, sponsored by St. Jude Children's Research Hospital.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 10 participants
- Enrollment target
- 1
- Study location
Study Summary
The study participant is being asked to take part in this clinical trial, a type of research study, because the participant has Gastrointestinal (GI) symptoms following a Hematopoietic Cell Transplant (HCT). Primary Objective * To determine the safety and feasibility of FMT for treating a GvHD of the gut following HCT. * To determine the safety and feasibility of FMT for treating HCT induced gut dysfunction. Secondary Objectives * To assess the potential efficacy of FMT for treating a GvHD of the gut following HCT. * To assess the potential efficacy of FMT for treating HCT induced gut dysfunction.
Primary Outcome
Serious adverse events will be a primary outcome measure for the following groups: * FMT for treating a GvHD of the gut following HCT * FMT for treating HCT induced gut dysfunction
Conditions Studied
Interventions
- DRUG Fecal microbiota transplant (FMT)
Study Locations (1)
Tennessee
- St. Jude Children's Research Hospital - Memphis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2025-07-07 |
| Est. Completion | 2028-12-31 |
| Phase | Phase 1 |
What NCT05664113 shows while recruiting
NCT05664113 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 183-participant average among 7 other Gastro-Intestinal Disorder trials with a reported enrollment target (95% lower).
The record links to 1 condition, with Gastro-Intestinal Disorder appearing as the primary indexed condition, and to 1 intervention - of which Fecal microbiota transplant (FMT) is the first listed.
NCT05664113 reports a single indexed study location in Tennessee.
Frequently Asked Questions
What is clinical trial NCT05664113 about?
NCT05664113 is a clinical study titled "Feasibility, Safety, and Potential Efficacy of Fecal Microbiota Transplantation (FMT) for Gastrointestinal Dysfunction in Children Following Hematopoietic Cell Transplant (HCT).". The study participant is being asked to take part in this clinical trial, a type of research study, because the participant has Gastrointestinal (GI) symptoms following a Hematopoietic Cell Transplant (HCT). Primary Objective * To determine the safety and feasibility of FMT for treating a GvHD of ...
What is the current status of trial NCT05664113?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 10 participants. The study started on 2025-07-07. Estimated completion is 2028-12-31.
What conditions does trial NCT05664113 study?
This clinical trial studies the following conditions: Gastro-Intestinal Disorder.
What interventions are being tested in trial NCT05664113?
The interventions under investigation include: Fecal microbiota transplant (FMT) (DRUG).
Who is sponsoring clinical trial NCT05664113?
This trial is sponsored by St. Jude Children's Research Hospital, which has 410 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05664113 being conducted?
This trial has 1 study location across Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Gastro-Intestinal Disorder
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
The Gut-Brain Study
ACTIVE NOT RECRUITING · Phase 1
-
Gastroparesis Registry 4
RECRUITING
-
MTT for Children With ASD Who Have Gastrointestinal Disorders
ACTIVE NOT RECRUITING · Phase 2
-
Microbiota Transplant Therapy for Children With Both Autism Spectrum Disorder and Gastrointestinal Disorders
ACTIVE NOT RECRUITING · Phase 2
-
Biological Sample Repository for Gastrointestinal Disorders
ACTIVE NOT RECRUITING
-
Microbiota Transfer Therapy for Adults With Autism Spectrum Disorder (ASD) Who Have Gastrointestinal Disorders
ACTIVE NOT RECRUITING · Phase 2
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT00623389 · 10 participants · NA
Evaluation of an Advanced Lower Extremity Neuroprostheses
- NCT01241864 · 10 participants · Phase 2
Islet Transplantation in Type 1 Diabetic Kidney Allograft
- NCT01293214 · 10 participants · NA
Vascularized Composite Allotransplantation for Multiple Extremity Amputations
- NCT01474148 · 10 participants · NA
A Neuroprosthesis for Seated Posture and Balance
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI