National Institutes of Health Clinical Center (CC)

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, National Institutes of Health Clinical Center (CC) sits in the top decile of US sponsors by registered trial count (#107 of 15,742 sponsors by registered trial count).

338 total trials 22 currently recruiting 272 completed early-phase tilt top decile by trial count

National Institutes of Health Clinical Center (CC): 338 sponsored US clinical trials, 22 recruiting.

National Institutes of Health Clinical Center (CC) sponsors 338 registered US clinical trials on ClinicalTrials.gov, 22 of them currently recruiting, and 272 completed. 17 of these trials are in Phase 3-4 (later-stage) and 121 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 8 trials.

Top-decile sponsor footprint

National Institutes of Health Clinical Center (CC) ranks in the top decile of sponsors by registered trial count (#107 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 60/100

272 of 308 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (88.3%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

338 total, page 6 of 7

COMPLETED Phase 1

CC-5013 in Treating Patients With Cancer That Has Not Responded to Previous Therapy

NCT00031941

COMPLETED

Constipation in Pediatric Cancer Patients Receiving Vinca Alkaloids or Narcotics

NCT00032682

COMPLETED Phase 1

ABT-751 in Treating Young Patients With Refractory Solid Tumors

NCT00036959

COMPLETED

Plasmapheresis of Anthrax-Vaccinated Subjects for Production of Anthrax Immune Globulin

NCT00031291

COMPLETED

Study of Transfusion-Transmitted Infections

NCT00023023

COMPLETED

Process and Outcomes of Pain Management

NCT00028249

COMPLETED

Morbidity After Diagnosis and Treatment of Breast Cancer Patients

NCT00027118

COMPLETED

Implementing the Assent Requirement for Research With Children

NCT00102076

COMPLETED

Morbidity Following the Diagnosis and Treatment of Patients With Breast Cancer

NCT00027105

COMPLETED Phase 1

Ixabepilone in Treating Young Patients With Solid Tumors or Leukemia That Haven't Responded to Therapy

NCT00030108

COMPLETED

Technology Dependency and Health-Related Quality of Life

NCT00022984

COMPLETED Phase 1

Epirubicin, Carboplatin, and Capecitabine in Treating Patients With Unresectable Locally Advanced, Metastatic, or Recurrent Solid Tumor

NCT00021047

COMPLETED Phase 1

Tipifarnib in Treating Young Patients With Refractory Leukemia

NCT00022451

COMPLETED

Identification of Donors of CD36-Deficient Platelets Among Japanese Individuals on the NIH Campus

NCT00015639

COMPLETED

Study of Tongue Pressures

NCT00013832

COMPLETED Phase 3

Chemotherapy With or Without Isolated Hepatic Perfusion With Melphalan in Treating Patients With Colorectal Cancer That Has Spread to the Liver

NCT00020501

COMPLETED Phase 1

MS-275 in Treating Patients With Advanced Solid Tumors or Lymphoma

NCT00020579

COMPLETED Phase 1

The Effect of Milk Thistle on the Pharmacokinetics of Indinavir

NCT00011635

COMPLETED Phase 1

Effect of Ginkgo Biloba on Phenytoin Elimination

NCT00011063

COMPLETED

Platelet Function in Patients Treated With SSRI and Non-SSRI Antidepressants

NCT00009568

COMPLETED Phase 4

Effects of Kava on the Body's Elimination of Caffeine and Dextromethorphan

NCT00009542

COMPLETED Phase 2

Nitric Oxide to Improve Blood Flow in Sickle Cell Disease

NCT00009581

COMPLETED

Structure and Function of the Human Tongue

NCT00007137

COMPLETED Phase 4

Drug Interaction Study of Tegretol (Carbamazepine) and St. John's Wort in Normal Volunteers

NCT00006395

COMPLETED

Effects of Fetal, Infant, and Early Childhood Exposures on Adult Cancer Risk in Women

NCT00559039

COMPLETED Phase 2

Combination Chemotherapy and Radiation Therapy Plus Surgery in Treating Patients With Advanced Cancer of the Pancreas

NCT00020345

COMPLETED

Role of Prostaglandins in the Regulation of Brain Blood Flow

NCT00006318

COMPLETED

Magnetic Resonance Imaging for Evaluating Kidney Function

NCT00006173

COMPLETED

Spleen Size in Peripheral Blood Stem Cell Donors

NCT00006148

COMPLETED NA

Complementary or Alternative Medicine Practices Used by Women at Increased Risk for Breast Cancer

NCT00020098

COMPLETED Phase 1

Inhaled Doxorubicin in Treating Patients With Advanced Solid Tumors Affecting the Lungs

NCT00020124

COMPLETED Phase 1

Endothelial Cell Dysfunction in Pulmonary Hypertension

NCT00098072

COMPLETED

Quality of Life in Patients With Chronic Ischemic Heart Disease

NCT00005671

COMPLETED

Brain Processing of Language Meanings

NCT00005004

COMPLETED

Study of Fetal Swallowing

NCT00004566

COMPLETED Phase 2

Docetaxel With or Without Thalidomide in Treating Patients With Metastatic Prostate Cancer

NCT00020046

COMPLETED

A Study of Health-Related Quality of Life in HIV-Infected Patients Undergoing Structured Treatment Interruptions of Highly Active Antiretroviral Therapy

NCT00001948

COMPLETED Phase 1

Comparison of Magnetic Resonance Angiography and Standard Angiography in Diagnosing Atherosclerosis

NCT00001946

COMPLETED

Nucleic Acid Amplification Testing (NAT) of Blood Donors for HCV and HIV

NCT00004846

COMPLETED

Comparison of Quality of Life in Patients Undergoing More Intensive Versus Less Intensive Chemotherapy and Radiation Preceding a Bone Marrow Transplant

NCT00004994

TERMINATED

Study of New Magnetic Resonance Methods

NCT00001844

COMPLETED

Study of Brain Blood Flow During Induced Hypercapnia (Excess Blood Carbon Dioxide)

NCT00001845

COMPLETED Phase 2

Monoclonal Antibody Plus Chemotherapy in Treating Patients With Metastatic Breast Cancer That Overexpresses HER2

NCT00019812

COMPLETED Phase 2

Isolated Hepatic Perfusion With Melphalan in Treating Patients With Primary Unresectable Liver Cancer or Liver Metastases

NCT00019786

TERMINATED Phase 2

Surgery With or Without Thalidomide in Treating Patients With Recurrent or Metastatic Colorectal Cancer

NCT00019747

TERMINATED

Factors Affecting Weight Gain in Women Receiving Adjuvant Chemotherapy for Breast Cancer

NCT00019643

COMPLETED Phase 1

G-CSF for Granulocyte Donation

NCT00001842

COMPLETED Phase 2

Isolated Hepatic Perfusion With Melphalan Followed By Chemotherapy in Treating Patients With Unresectable Colorectal Cancer That is Metastatic to the Liver

NCT00019760

COMPLETED

Generation of Anti-HCV Antibodies From Bone Marrow: Defining the Repertoire of Immune Response to HCV Quasispecies

NCT00004851

COMPLETED

A Family Study of Adults With Glioma

NCT00339352

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Phase Distribution

PhaseTrial count
Phase 1 74
Phase 2 47
Phase 3 6
Phase 4 11

What is open in the National Institutes of Health Clinical Center (CC) pipeline

22 recruiting of 338 indexed (7% open); 272 completed (80%).

Phase mix: 17 late (III/IV) vs 121 early (I/II) (early-phase heavy).

Top condition: Healthy (8 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

National Institutes of Health Clinical Center (CC): open-pipeline peers nationwide

Peers matched on 338 registered trials and 7% open enrollment, not the therapeutic-area sidebar.

National Institutes of Health Clinical Center (CC) sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0100200300400500 0%5%10%15%20%25% Total trials Recruiting share National Institutes of Health Clinical Center (CC)Cedars-Sinai Medical CenterOhio State University Comprehensive Cancer CenterNational Institute on Drug Abuse (NIDA)Children's Oncology GroupAlliance for Clinical Trials in OncologyNICHD Neonatal Research NetworkInsmed IncorporatedBaylor Breast Care Center
National Institutes of Health Clinical Center (CC) sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

National Institutes of Health Clinical Center (CC) sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 338 trials (± recruiting share)

Sponsors near 7% open enrollment (± trial volume)

What to do with this National Institutes of Health Clinical Center (CC) page

338 registered trials is a research-attention snapshot, not an endorsement of National Institutes of Health Clinical Center (CC) or any single study.

  • 22 of National Institutes of Health Clinical Center (CC)'s trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Healthy is the condition National Institutes of Health Clinical Center (CC) studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Healthy trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. National Institutes of Health Clinical Center (CC) pipeline card: 338 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.