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NCT00006173 · ClinicalTrials.gov registry record
Magnetic Resonance Imaging for Evaluating Kidney Function
A clinical trial of Healthy and Renovascular Hypertension, sponsored by National Institutes of Health Clinical Center (CC).
- Completed
- Registry status
- 40
- Enrollment target
- 1
- Study location
NCT00006173: Completed study of Healthy and Renovascular Hypertension, sponsored by National Institutes of Health Clinical Center (CC).
NCT00006173 is a study of Healthy and Renovascular Hypertension that has completed, run by National Institutes of Health Clinical Center (CC). The registered enrollment target is 40 participants, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00006173, a study of Healthy and Renovascular Hypertension, has completed, sponsored by National Institutes of Health Clinical Center (CC).
- COMPLETED
- Registry status
- 40 participants
- Enrollment target
- 1
- Study location
Study Summary
Renovascular hypertension (RVH) is a potentially curable disease affecting 0.5-5 percent of patients with hypertension. The current diagnostic work-up of RVH involves a complex algorithm which includes doppler ultrasound, captopril renography and conventional angiography. Because of the expense, risk and inconvenience of this workup, patients may not be correctly diagnosed. Advances in MR technology present the opportunity to develop a single comprehensive test. This would combine an MR angiogram that provides anatomic information about the renal arteries, and an MR renogram that provides information about the functional impact of a stenosis as a cause of hypertension. Our main purpose is to test MR renography with and without an oral angiotensin converting enzyme inhibitor (ACEI) combined with MR angiography against the reference standard of captopril radionuclide renography. Secondary goals of this study are to test whether hypoxia within ischemic kidneys affected by RVH is detectable by T2 weighted (Blood oxygen level dependent or BOLD) MRI. This is considered of value since such a test of oxygenation would further shorten and simplify the diagnostic MR test. Information gained from this study could lead to important changes in the diagnostic and pathophysiologic understanding of RVH.
Conditions Studied
Study Locations (1)
Maryland
- Warren G. Magnuson Clinical Center (CC) - Bethesda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2000-08 |
| Est. Completion | 2004-01 |
What the finished NCT00006173 record still lists
NCT00006173 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (94% lower).
The record links to 2 conditions, with Healthy appearing as the primary indexed condition, and to 0 interventions.
NCT00006173 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT00006173 about?
NCT00006173 is a clinical study titled "Magnetic Resonance Imaging for Evaluating Kidney Function". Renovascular hypertension (RVH) is a potentially curable disease affecting 0.5-5 percent of patients with hypertension. The current diagnostic work-up of RVH involves a complex algorithm which includes doppler ultrasound, captopril renography and conventional angiography. Because of the expense, ris...
What is the current status of trial NCT00006173?
This trial is currently completed. The enrollment target is 40 participants. The study started on 2000-08. Estimated completion is 2004-01.
What conditions does trial NCT00006173 study?
This clinical trial studies the following conditions: Healthy, Renovascular Hypertension.
Who is sponsoring clinical trial NCT00006173?
This trial is sponsored by National Institutes of Health Clinical Center (CC), which has 338 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00006173 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT00006173's enrollment target sits among peer trials
40 540th of 1090 higher than 513 of 1,090 other Healthy trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Healthy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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