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NCT00009568 · ClinicalTrials.gov registry record
Platelet Function in Patients Treated With SSRI and Non-SSRI Antidepressants
A clinical trial of Depression, sponsored by National Institutes of Health Clinical Center (CC).
- Completed
- Registry status
- 70
- Enrollment target
- 1
- Study location
NCT00009568: Completed study of Depression, sponsored by National Institutes of Health Clinical Center (CC).
NCT00009568 is a study of Depression that has completed, run by National Institutes of Health Clinical Center (CC). The registered enrollment target is 70 participants, below the 786-participant average among 679 other Depression trials with a reported enrollment target (91% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00009568, a study of Depression, has completed, sponsored by National Institutes of Health Clinical Center (CC).
- COMPLETED
- Registry status
- 70 participants
- Enrollment target
- 1
- Study location
Study Summary
This study will examine the effect of a class of antidepressant medications called selective serotonin reuptake inhibitors (SSRIs) on platelet function. Platelets are small blood cells that help stop bleeding after injury to a blood vessel by forming a clot, or plug, in the vessel. Some medications impair platelet function, leading to increased bruising and bleeding. SSRIs decrease an important platelet component called serotonin, which may cause bleeding in some patients. SSRIs include fluoxetine (Prozac), sertraline (Zoloft), paroxetine (Paxil), fluvoxamine (Luvox) and citalopram (Celexa). Patients 18 years of age and older being treated for depression with a SSRI or the non-SSRI bupropion (Wellbutrin) may be eligible for this study. Subjects will be recruited from a private clinic in Washington, D.C. Participants will provide a history of their current medications and past history of bleeding. They will have about 4 tablespoons of blood drawn for tests to measure blood cell counts and platelet function. The study takes about 1 hour. The results of the SSRI-treated group and the bupropion-treated group will be analyzed and compared. This study may provide information that will help health care providers make treatment decisions to minimize possible adverse effects of medications in patients with depression.
Conditions Studied
Study Locations (1)
Maryland
- Warren G. Magnuson Clinical Center (CC) - Bethesda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 70 participants |
| Start Date | 2001-01 |
| Est. Completion | 2005-01 |
What the finished NCT00009568 record still lists
NCT00009568 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 70 participants, a relatively small participant target, below the 786-participant average among 679 other Depression trials with a reported enrollment target (91% lower).
The record links to 1 condition, with Depression appearing as the primary indexed condition, and to 0 interventions.
NCT00009568 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT00009568 about?
NCT00009568 is a clinical study titled "Platelet Function in Patients Treated With SSRI and Non-SSRI Antidepressants". This study will examine the effect of a class of antidepressant medications called selective serotonin reuptake inhibitors (SSRIs) on platelet function. Platelets are small blood cells that help stop bleeding after injury to a blood vessel by forming a clot, or plug, in the vessel. Some medications ...
What is the current status of trial NCT00009568?
This trial is currently completed. The enrollment target is 70 participants. The study started on 2001-01. Estimated completion is 2005-01.
What conditions does trial NCT00009568 study?
This clinical trial studies the following conditions: Depression.
Who is sponsoring clinical trial NCT00009568?
This trial is sponsored by National Institutes of Health Clinical Center (CC), which has 338 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00009568 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Depression
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00009568's enrollment target sits among peer trials
70 407th of 679 higher than 266 of 679 other Depression trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Depression trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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