National Institutes of Health Clinical Center (CC)

338 total trials 22 currently recruiting 272 completed

National Institutes of Health Clinical Center (CC) sponsors 338 registered US clinical trials on ClinicalTrials.gov, 22 of them currently recruiting, and 272 completed. 17 of these trials are in Phase 3-4 (later-stage) and 121 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 8 trials.

Trial Pipeline

338 total, page 5 of 7

COMPLETED

Influence of Genes on Sirolimus Metabolism in Patients With Kidney Transplantation

NCT00352547

COMPLETED Phase 1

Gefitinib, Paclitaxel, and Radiation Therapy in Treating Patients With Advanced or Recurrent Squamous Cell Carcinoma of the Head and Neck

NCT00083057

COMPLETED

Isoproterenol Challenge to Detect Arrhythmogenic Right Ventricular Cardiomyopathy

NCT00083395

COMPLETED Phase 1

Gene-Modified White Blood Cells Followed By Interleukin-2 and Vaccine Therapy in Treating Patients With Metastatic Melanoma

NCT00085462

COMPLETED Phase 3

Oral Care to Reduce Mouth and Throat Infections in Critically Ill Patients

NCT00078663

COMPLETED Phase 2

Monoclonal Antibody With or Without gp100 Peptides Plus Montanide ISA-51 in Treating Patients With Stage IV Melanoma

NCT00077532

COMPLETED Phase 2

Docetaxel, Estramustine, and Thalidomide in Treating Patients With Androgen-Independent Metastatic Adenocarcinoma of the Prostate

NCT00083005

COMPLETED

Patient-Provider Trust Among Individuals With End-Stage Kidney Disease

NCT00075036

COMPLETED

Magnetic Resonance Imaging to Evaluate Prostate Cancer

NCT00182624

COMPLETED NA

Sentinel Lymph Node Biopsy and Primary Tumor Gene Expression Profiling in Finding Axillary Lymph Node Metastases in Women Who Have Received Neoadjuvant Therapy for Stage II, Stage III, or Stage IV Breast Cancer

NCT00080860

COMPLETED Phase 1

Peptide Vaccine to Prevent Recurrence of Nasopharyngeal Cancer

NCT00078494

COMPLETED NA

Bupropion and Counseling With or Without Contingency Management to Enhance Smoking Cessation in Treating Cancer Survivors Who Continue to Smoke

NCT00079469

COMPLETED Phase 1

T-Cell-Depleted Allogeneic Stem Cell Transplantation After Immunoablative Induction Chemotherapy and Reduced-Intensity Transplantation Conditioning in Treating Patients With Hematologic Malignancies

NCT00080925

COMPLETED

Clinical Evaluations and Laboratory Studies to Study the Disease Course in Patients With Cutaneous T-Cell Lymphoma

NCT00430053

COMPLETED Phase 1

The Effect of Lopinavir/Ritonavir on Endothelial Function

NCT00076414

COMPLETED

Genetic Study to Identify Gene Mutations in Participants Previously Enrolled in Clinical Trial NCI-99-C-0053 Who Have Von Hippel-Lindau Syndrome or Are at Risk for Von Hippel-Lindau Syndrome

NCT00075348

COMPLETED

Citrate Effects and Bone Density in Long-Term Apheresis Donors

NCT00073060

COMPLETED Phase 1

Atorvastatin Therapy to Improve Endothelial Function in Sickle Cell Disease

NCT00072826

COMPLETED

Pharmacokinetic Interactions With Prednisolone in Healthy Volunteers and HIV-infected Patients Receiving Single-Dose Prednisone

NCT00072644

COMPLETED

Protein Studies of the Epstein-Barr Virus in Ethnically Diverse Populations

NCT00070785

COMPLETED Phase 2

Omr-IgG-am(Trademark) for Treating Patients With or at High Risk for West Nile Virus Disease

NCT00069316

COMPLETED

Health Beliefs and Health Behaviors Among Minorities With Rheumatic Diseases

NCT00069342

COMPLETED

Natural History of West Nile Virus Infection

NCT00069303

COMPLETED

MR Perfusion Imaging and Hypercapnia (Increased Carbon Dioxide) to Study New Blood Vessel Formation in Multiple Sclerosis

NCT00064909

COMPLETED Phase 1

Ravuconazole in Preventing Fungal Infections in Patients Undergoing Allogeneic Stem Cell Transplantation

NCT00064311

COMPLETED NA

Serum Protein Patterns in Participants With Mycosis Fungoides/Cutaneous T-Cell Lymphoma, Psoriasis, or Normal Skin

NCT00066664

COMPLETED Phase 1

Cyclophosphamide and Fludarabine Followed By Interleukin-2 Gene-Modified Tumor Infiltrating Lymphocytes in Treating Patients With Metastatic Melanoma

NCT00062036

COMPLETED Phase 2

Talampanel in Treating Patients With Recurrent High-Grade Glioma

NCT00064363

COMPLETED

Study of Heart Transplant Rejection

NCT00042614

COMPLETED Phase 1

Interleukin-7 in Treating Patients With Refractory Solid Tumors

NCT00062049

COMPLETED

Breathing Cycle Biofeedback During Computed Tomography Procedures

NCT00059137

COMPLETED

Development of Computer-aided Detection and Diagnosis From Imaging Techniques

NCT00057252

COMPLETED Phase 1

Evaluation of Hydroxyurea Plus L-arginine or Sildenafil to Treat Sickle Cell Anemia

NCT00056433

COMPLETED Phase 1

Low-Dose rtPA to Treat Blood Clots in Major Arm or Neck Veins

NCT00055159

COMPLETED Phase 4

Differences in Blood Levels of Nevirapine in HIV-infected Patients in Uganda and the United States

NCT00054743

COMPLETED Phase 2

Monoclonal Antibody Therapy in Treating Patients With Metastatic Renal Cell Cancer

NCT00057889

COMPLETED NA

Study of Decision Making in Patients Participating in Phase I Clinical Trials

NCT00054223

COMPLETED Phase 4

Influence of the MDR1 Genotype on Blood Levels of Indinavir and Saquinavir in Healthy Volunteers

NCT00050180

COMPLETED Phase 2

Daclizumab to Treat Chronic Immune Thrombocytopenia

NCT00049725

COMPLETED

Relationship Between Personality and Coping Styles in Bone Marrow Transplant Candidates

NCT00048256

COMPLETED

Ethical Dilemmas in Clinical Practice: A Survey of European Physicians

NCT00352573

COMPLETED Phase 1

Monoclonal Antibody Therapy in Treating Patients With Lymphoma or Colon Cancer That Has Not Responded to Vaccine Therapy

NCT00047164

COMPLETED

The Natural History of Upper Trapezius Myofascial Trigger Points: Comparison of Local and Remote Tissue Milieu in Normal Muscle, Latent and Active Myofascial Trigger Points Over Time

NCT00042276

COMPLETED

Radiofrequency Ablation of Painful Soft Tissue Neoplasms

NCT00041886

COMPLETED NA

Evaluating Patient Participation in Phase I Clinical Trials

NCT00043030

COMPLETED Phase 3

Magnesium Effects in Apheresis

NCT00040235

COMPLETED Phase 1

Endothelial Dysfunction as a Risk Factor in HIV Study

NCT00039663

COMPLETED

Pilot Study: Effects of G-CSF on T Cell Function

NCT00039650

COMPLETED Phase 2

Heparin Versus Lepirudin Flushes in Preventing Blockage of Venous Access Devices

NCT00039767

COMPLETED Phase 4

Valganciclovir to Prevent Cytomegalovirus Infection in Kidney and Kidney/Pancreas Transplant Recipients

NCT00034385

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Phase Distribution

PhaseTrial count
Phase 1 74
Phase 2 47
Phase 3 6
Phase 4 11

What the Pipeline for National Institutes of Health Clinical Center (CC) Shows

According to the ClinicalTrials.gov registry, National Institutes of Health Clinical Center (CC) is linked to 338 US clinical trials across every stage of research activity. Of those, 22 studies are currently recruiting, about 7% of the sponsor's indexed portfolio, and 272 are already marked complete, representing roughly 80% of the total.

The phase mix for National Institutes of Health Clinical Center (CC) reports 17 late-stage studies (Phase 3 and Phase 4 combined) and 121 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for National Institutes of Health Clinical Center (CC) is Healthy with 8 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.