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NCT00007137 · ClinicalTrials.gov registry record
Structure and Function of the Human Tongue
A clinical trial of Healthy, sponsored by National Institutes of Health Clinical Center (CC).
- Completed
- Registry status
- 165
- Enrollment target
- 1
- Study location
NCT00007137: Completed study of Healthy, sponsored by National Institutes of Health Clinical Center (CC).
NCT00007137 is a study of Healthy that has completed, run by National Institutes of Health Clinical Center (CC). The registered enrollment target is 165 participants, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (74% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00007137, a study of Healthy, has completed, sponsored by National Institutes of Health Clinical Center (CC).
- COMPLETED
- Registry status
- 165 participants
- Enrollment target
- 1
- Study location
Study Summary
This study will use magnetic resonance imaging (MRI) and ultrasound to examine changes in tongue volume and blood circulation during tongue exercises that require the use of different tongue muscle movements and contractions. More information on the structure and function of the human tongue is needed to develop better treatments for people with certain diseases affecting speech and swallowing. Normal volunteers between 21 and 80 years old who live in the metropolitan Washington, D.C., area may be eligible for this study. Candidates will be screened with a brief medical history and physical examination, including suitability for MRI testing, and a brief examination of tongue, lip and jaw movements. Participants will undergo ultrasound and MRI studies. During both tests, they will perform tongue exercises, such as holding a soft round object on the tongue or exerting tongue pressure against the back of the throat or roof of the mouth. During the ultrasound, the subject lies on a flattened dental chair. A small transducer is placed under the chin to take images of the tongue during the exercises. A thin rubber strip with air-filled pressure bulbs is attached to the roof of the mouth (with dental adhesive) to measure tongue pressure. For the MRI, the subject lies on a table that slides inside a donut's machine containing a magnetic field. MRI coils-special padded sensors that improve image quality-are placed around the head and neck. A pressure cuff placed around the arm measures blood pressure. The subject wears earplugs to muffle loud thumping noises that occur during electrical switching of the magnetic fields. The subject is in constant visual contact with the researchers and MR technologist and may request to stop the study at any time. Participants may undergo another procedure, called magnetic resonance diffusion tensor imaging, to examine how the fluid (water) in the tongue tissue shifts during tongue maneuvers. This procedure is essentially the same as th
Conditions Studied
Study Locations (1)
Maryland
- National Institutes of Health Clinical Center, 9000 Rockville Pike - Bethesda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 165 participants |
| Start Date | 2000-12-05 |
| Est. Completion | 2007-04-11 |
What the finished NCT00007137 record still lists
NCT00007137 is an observational study that tracks outcomes without assigning an intervention. The registered 165 participants enrollment target is mid-sized for trials with a published cap, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (74% lower).
The record links to 1 condition, with Healthy appearing as the primary indexed condition, and to 0 interventions.
NCT00007137 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT00007137 about?
NCT00007137 is a clinical study titled "Structure and Function of the Human Tongue". This study will use magnetic resonance imaging (MRI) and ultrasound to examine changes in tongue volume and blood circulation during tongue exercises that require the use of different tongue muscle movements and contractions. More information on the structure and function of the human tongue is need...
What is the current status of trial NCT00007137?
This trial is currently completed. The enrollment target is 165 participants. The study started on 2000-12-05. Estimated completion is 2007-04-11.
What conditions does trial NCT00007137 study?
This clinical trial studies the following conditions: Healthy.
Who is sponsoring clinical trial NCT00007137?
This trial is sponsored by National Institutes of Health Clinical Center (CC), which has 338 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00007137 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT00007137's enrollment target sits among peer trials
165 143rd of 1090 higher than 948 of 1,090 other Healthy trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Healthy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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