NICHD Neonatal Research Network

Open enrollment with a later-stage pipeline tilt

According to ClinicalTrials.gov-derived indexes, NICHD Neonatal Research Network sits in the top decile of US sponsors by registered trial count (#334 of 15,742 sponsors by registered trial count).

61 total trials 4 currently recruiting 45 completed later-stage tilt top decile by trial count

NICHD Neonatal Research Network: 61 sponsored US clinical trials, 4 recruiting.

NICHD Neonatal Research Network sponsors 61 registered US clinical trials on ClinicalTrials.gov, 4 of them currently recruiting, and 45 completed. 21 of these trials are in Phase 3-4 (later-stage) and 13 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Infant, Small for Gestational Age, with 13 trials.

Top-decile sponsor footprint

NICHD Neonatal Research Network ranks in the top decile of sponsors by registered trial count (#334 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 48/100

45 of 54 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (83.3%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

61 total, page 1 of 2

RECRUITING NA

Neonatal Platelet Transfusion Threshold Trial

NCT06676904

RECRUITING Phase 3

Milrinone for Prevention of Post-ligation Cardiac Syndrome Trial

NCT06679855

RECRUITING

Follow-up Visit of High Risk Infants

NCT00009633

RECRUITING

Generic Database of Very Low Birth Weight Infants

NCT00063063

ACTIVE NOT RECRUITING Phase 3

The Budesonide in Babies (BiB) Trial

NCT04545866

ACTIVE NOT RECRUITING NA

Cycled Phototherapy

NCT03927833

ACTIVE NOT RECRUITING Phase 3

Management of the PDA Trial

NCT03456336

TERMINATED Phase 3

Moderately Preterm Infants With Caffeine at Home for Apnea (MoCHA) Trial

NCT03340727

COMPLETED Phase 2

Milrinone in Congenital Diaphragmatic Hernia

NCT02951130

COMPLETED Phase 3

Darbepoetin Trial to Improve Red Cell Mass and Neuroprotection in Preterm Infants

NCT03169881

COMPLETED NA

Preemie Hypothermia for Neonatal Encephalopathy

NCT01793129

COMPLETED

Early-Onset Sepsis an NICHD/CDC Surveillance Study

NCT02410486

COMPLETED NA

Incubator Weaning of Moderately Preterm Infants

NCT02160002

COMPLETED Phase 3

Hydrocortisone for Term Hypotension

NCT01954056

TERMINATED Phase 3

Inositol to Reduce Retinopathy of Prematurity

NCT01954082

COMPLETED NA

Transfusion of Prematures Trial

NCT01702805

COMPLETED Phase 3

Donor Milk vs. Formula in Extremely Low Birth Weight (ELBW) Infants

NCT01534481

COMPLETED

Generic Database of Moderate Preterm Infants

NCT01793116

TERMINATED Phase 2

Inhaled Prostaglandin E1 (IPGE1) for Hypoxemic Respiratory Failure (NHRF)

NCT01467076

COMPLETED Phase 3

Hydrocortisone for BPD

NCT01353313

COMPLETED Phase 1

Vitamin E for Extremely Preterm Infants

NCT01193270

TERMINATED NA

Optimizing (Longer, Deeper) Cooling for Neonatal Hypoxic-Ischemic Encephalopathy(HIE)

NCT01192776

COMPLETED NA

Laparotomy vs. Drainage for Infants With Necrotizing Enterocolitis

NCT01029353

COMPLETED Phase 2

Multi-dose Pharmacokinetics and Dose Ranging of Inositol in Premature Infants (INS-2)

NCT01030575

COMPLETED

Cerebral Function Monitoring in Premature Infants

NCT00873847

COMPLETED Phase 1

Early Blood Pressure Management in Extremely Premature Infants

NCT00874393

COMPLETED

Hypotension in Neonates

NCT00882284

COMPLETED NA

Late Hypothermia for Hypoxic-Ischemic Encephalopathy

NCT00614744

COMPLETED Phase 2

Single-Dose Intravenous Inositol Pharmacokinetics in Preterm Infants

NCT00349726

COMPLETED

Early-Onset Sepsis Surveillance Study

NCT00874367

COMPLETED

Physiologic Definition of Bronchopulmonary Dysplasia

NCT01223287

COMPLETED Phase 3

Surfactant Positive Airway Pressure and Pulse Oximetry Trial

NCT00233324

COMPLETED

Immunogenicity of PCV-7 Vaccine in VLBW Infants

NCT00273325

COMPLETED

Early Diagnosis of Candidiasis in Premature Infants

NCT00109525

COMPLETED Phase 3

Trial of Aggressive Versus Conservative Phototherapy in Infants <1,000 Grams Birth Weight

NCT00114543

COMPLETED Phase 1

Delivery Room CPAP in Extremely Low Birth Weight Infants

NCT01223274

COMPLETED NA

Benchmarking Initiative to Reduce Bronchopulmonary Dysplasia

NCT00067613

COMPLETED

Observational Study of Surgical Treatment of Necrotizing Enterocolotis

NCT01223261

TERMINATED Phase 3

Inhaled Nitric Oxide for Preterm Infants With Severe Respiratory Failure

NCT00016523

COMPLETED Phase 1

Delayed Cord Clamping in VLBW Infants

NCT01222364

TERMINATED Phase 3

Early Surfactant to Reduce Use of Mechanical Breathing in Low Birth Weight Infants

NCT00005774

COMPLETED Phase 3

Whole-Body Cooling for Birth Asphyxia in Term Infants

NCT00005772

COMPLETED

Inflammatory Cytokines Associated With Perinatal Brain Injury

NCT01035697

COMPLETED Phase 3

Glutamine Supplementation to Prevent Death or Infection in Extremely Premature Infants

NCT00005775

TERMINATED Phase 3

Early Inhaled Nitric Oxide for Respiratory Failure in Newborns

NCT00005773

TERMINATED Phase 3

Minimal Breathing Support and Early Steroids to Prevent Chronic Lung Disease in Extremely Premature Infants (SAVE)

NCT00005777

COMPLETED Phase 2

The Effects of Erythropoietin (EPO) on the Transfusion Requirements of Very Low Birth Weight Infants

NCT01203514

COMPLETED

In Utero Magnesium Sulfate Exposure: Effects on Extremely-Low-Birth-Weight Infants

NCT01203501

COMPLETED Phase 1

Vitamin A Supplementation for Extremely-Low-Birth-Weight Infants

NCT01203488

TERMINATED Phase 3

Inhaled Nitric Oxide Study for Respiratory Failure in Newborns

NCT00005776

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Where NICHD Neonatal Research Network enrollment is open (later-stage tilt)

4 recruiting of 61 indexed (7% open); 45 completed (74%).

Phase mix: 21 late (III/IV) vs 13 early (I/II) (later-stage heavy).

Top condition: Infant, Small for Gestational Age (13 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

NICHD Neonatal Research Network: open-pipeline peers nationwide

Peers matched on 61 registered trials and 7% open enrollment, not the therapeutic-area sidebar.

NICHD Neonatal Research Network sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0100200300400500 0%5%10%15%20%25% Total trials Recruiting share NICHD Neonatal Research NetworkEndo USA Inc., a Keenova Therapeutics CompanyOregon Research InstitutePower Life SciencesHenry M. Jackson Foundation for the Advancement of Military MedicineNational Institutes of Health Clinical Center (CC)Alliance for Clinical Trials in OncologyInsmed IncorporatedBaylor Breast Care Center
NICHD Neonatal Research Network sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

NICHD Neonatal Research Network sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 61 trials (± recruiting share)

Sponsors near 7% open enrollment (± trial volume)

What to do with this NICHD Neonatal Research Network page

61 registered trials is a research-attention snapshot, not an endorsement of NICHD Neonatal Research Network or any single study.

  • 4 of NICHD Neonatal Research Network's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Infant, Small for Gestational Age is the condition NICHD Neonatal Research Network studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Infant, Small for Gestational Age trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

NICHD Neonatal Research Network pipeline card: 61 registered trials from official public datasets.Report a data error.