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NCT00001845 · ClinicalTrials.gov registry record
Study of Brain Blood Flow During Induced Hypercapnia (Excess Blood Carbon Dioxide)
A clinical trial of Healthy and Hypercapnia, sponsored by National Institutes of Health Clinical Center (CC).
- Completed
- Registry status
- 30
- Enrollment target
- 1
- Study location
NCT00001845: Completed study of Healthy and Hypercapnia, sponsored by National Institutes of Health Clinical Center (CC).
NCT00001845 is a study of Healthy and Hypercapnia that has completed, run by National Institutes of Health Clinical Center (CC). The registered enrollment target is 30 participants, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00001845, a study of Healthy and Hypercapnia, has completed, sponsored by National Institutes of Health Clinical Center (CC).
- COMPLETED
- Registry status
- 30 participants
- Enrollment target
- 1
- Study location
Study Summary
This study will evaluate magnetic resonance imaging (MRI ) methods for measuring changes in the brain's blood flow during hypercapnia (a condition of excess carbon dioxide in the blood). MRI is a diagnostic tool that uses a large magnet and radio waves to produce images of the body without X-rays. Healthy normal volunteers in this study may have as many as six MRI scans over a 2-year period. For this procedure, the person lies on a stretcher placed in a strong magnetic field produced by the MRI machine. During the scan, the person's blood carbon dioxide (CO2 ) levels will be increased either by: 1) breathing air mixtures containing up to 5% CO2; or 2) receiving an intravenous (I.V.) injection of a drug called acetazolamide. Persons who breathe CO2 will have their heart rate, blood pressure and oxygen levels monitored throughout the procedure. Those receiving acetazolamide will have the drug injected intravenously (I.V.) into an arm vein. If the volunteer experiences any unpleasant side effects from the CO2 or acetazolamide, the study will be stopped. The information gained from this study will be used to develop better ways to study brain function, possibly leading to better diagnostic and treatment methods.
Conditions Studied
Study Locations (1)
Maryland
- Warren G. Magnuson Clinical Center (CC) - Bethesda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 1999-09 |
| Est. Completion | 2004-08 |
What the finished NCT00001845 record still lists
NCT00001845 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (95% lower).
The record links to 2 conditions, with Healthy appearing as the primary indexed condition, and to 0 interventions.
NCT00001845 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT00001845 about?
NCT00001845 is a clinical study titled "Study of Brain Blood Flow During Induced Hypercapnia (Excess Blood Carbon Dioxide)". This study will evaluate magnetic resonance imaging (MRI ) methods for measuring changes in the brain's blood flow during hypercapnia (a condition of excess carbon dioxide in the blood). MRI is a diagnostic tool that uses a large magnet and radio waves to produce images of the body without X-rays. ...
What is the current status of trial NCT00001845?
This trial is currently completed. The enrollment target is 30 participants. The study started on 1999-09. Estimated completion is 2004-08.
What conditions does trial NCT00001845 study?
This clinical trial studies the following conditions: Healthy, Hypercapnia.
Who is sponsoring clinical trial NCT00001845?
This trial is sponsored by National Institutes of Health Clinical Center (CC), which has 338 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00001845 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT00001845's enrollment target sits among peer trials
30 678th of 1090 higher than 363 of 1,090 other Healthy trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Healthy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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