National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) sits in the top decile of US sponsors by registered trial count (#74 of 15,742 sponsors by registered trial count).

490 total trials 50 currently recruiting 398 completed early-phase tilt top decile by trial count

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK): 490 sponsored US clinical trials, 50 recruiting.

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) sponsors 490 registered US clinical trials on ClinicalTrials.gov, 50 of them currently recruiting, and 398 completed. 69 of these trials are in Phase 3-4 (later-stage) and 178 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Obesity, with 25 trials.

Top-decile sponsor footprint

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) ranks in the top decile of sponsors by registered trial count (#74 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

C 74/100

398 of 424 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (93.9%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

490 total, page 9 of 10

COMPLETED NA

Biofeedback for Fecal Incontinence

NCT00124904

COMPLETED Phase 1

Underlying Abnormalities in Fat and Muscle Leading to Lipodystrophy Syndrome

NCT00006185

COMPLETED Phase 2

Sandostatin LAR Depot vs. Surgery for Treating Acromegaly

NCT00001860

COMPLETED Phase 2

Can Parathyroid Hormone Injections Reverse Glucocorticoid-induced Osteoporosis

NCT00004993

COMPLETED Phase 3

Saw Palmetto Extract in Benign Prostatic Hyperplasia

NCT00037154

COMPLETED

Monitoring for Tolerance to Kidney or Combined Kidney-Pancreas Transplants

NCT00001858

COMPLETED

Screening for Patients Needing Kidney, Kidney-Pancreas, or Islet-Cell Transplant

NCT00001859

COMPLETED Phase 2

PTHrP and Osteoporosis

NCT00021827

COMPLETED

Live Donors for Kidney Transplants

NCT00001856

COMPLETED Phase 2

Study Comparing the Safety of BG9588 (Anti-CD40L Antibody) Against Standard Treatment in Kidney Transplantation

NCT00001857

COMPLETED Phase 4

Long-Term Therapy With Ribavirin for Chronic Hepatitis C

NCT00001854

COMPLETED Phase 3

Treatment of Non-Cardiac Chest Pain With Imipramine or Cognitive-Behavioral Therapy

NCT00005575

COMPLETED Phase 1

Combination Iron Chelation Therapy

NCT00004982

TERMINATED Phase 2

Pilot Study of Atorvastatin in Children With Chronic Hyperlipidemia Secondary to Nephrotic Syndrome

NCT00004466

COMPLETED Phase 2

AIDS Wasting in Women: Anabolic Effects of Testosterone

NCT00006158

COMPLETED Phase 3

Randomized Study of Acetylcysteine in Patients With Acute Liver Failure Not Caused by Acetaminophen

NCT00004467

COMPLETED Phase 4

Preventing Depression Recurrence in Diabetes

NCT00374426

COMPLETED NA

Treatment of Bulimia Nervosa in a Primary Care Setting

NCT00009178

COMPLETED Phase 4

Nutrition Intervention in AIDS Wasting

NCT00006167

COMPLETED Phase 4

Study of Radioiodine (131-I) Uptake Following Administration of Thyrogen and Hypothyroid States During Thyroid Hormone Withdrawal.

NCT00001730

COMPLETED Phase 2

Alternate Day Prednisone or Daily Fish Oil Supplements in Patients With Immunoglobulin A Nephropathy

NCT00004448

COMPLETED

Risk Factors for Gastric Disease in Pediatric Helicobacter Pylori (H. Pylori)

NCT00212225

COMPLETED Phase 3

Combination Drug Therapy for Patients With Hepatitis C

NCT00001729

COMPLETED Phase 4

Computer-assisted Diabetes Self-management Interventions

NCT00006163

COMPLETED

Studies of States With Resistance to Vitamin D and Parathyroid Hormone

NCT00001242

TERMINATED Phase 3

Phase III Randomized Study of SYNSORB Pk in Children With E. Coli-Associated Hemolytic Uremic Syndrome

NCT00004465

COMPLETED

Human Sperm Binding to Transgenic Mouse Eggs

NCT00340587

COMPLETED Phase 1

Pilot Study of Budesonide for Patients With Primary Sclerosing Cholangitis

NCT00004842

COMPLETED Phase 3

North American Study for the Treatment of Refractory Ascites (NASTRA)

NCT00006166

COMPLETED Phase 1

The Body's Affect on Vitamin C

NCT00001309

COMPLETED Phase 3

Decompression Intervention of Variceal Rebleeding Trial (DIVERT)

NCT00006161

COMPLETED

Insulin Secretory Defects in Pima Indians at High Risk for NIDDM

NCT00410800

COMPLETED Phase 3

Treatment of Functional Bowel Disorders

NCT00006157

COMPLETED Phase 3

Diabetes Prevention Program

NCT00004992

COMPLETED Phase 3

Behavioral Treatment of Weight Gain in CF

NCT00006169

COMPLETED

Pathogenesis of Glomerulosclerosis

NCT00001392

COMPLETED

Genetic Markers for Focal Segmental Glomerulosclerosis

NCT00001393

COMPLETED Phase 3

Medical Therapy of Prostatic Symptoms

NCT00021814

COMPLETED Phase 2

Lamivudine for Chronic Hepatitis B

NCT00001457

COMPLETED Phase 3

Renoprotection in Early Diabetic Nephropathy in Pima Indians

NCT00340678

COMPLETED Phase 1

Phase I/II Randomized, Placebo-Controlled Study of Capsaicin for Interstitial Cystitis and Vulvar Vestibulitis

NCT00004316

COMPLETED NA

Effect of Dialysis Dose and Membrane Flux in Maintenance Hemodialysis

NCT00004285

COMPLETED NA

Lifestyle Interventions to Reduce Diabetes Risk

NCT00006162

COMPLETED

Delaying the Progression of Diabetic Nephropathy in Pima Indians

NCT00353600

COMPLETED

Using X-Ray Dye to Locate Hidden Parathyroid Tumors

NCT00001394

COMPLETED NA

Family-Centered Diabetes Project

NCT00006159

COMPLETED Phase 3

The Diabetes Prevention Trial of Type 1 Diabetes (DPT-1)

NCT00004984

COMPLETED Phase 3

Ursodiol-Methotrexate for Primary Biliary Cirrhosis

NCT00006168

COMPLETED Phase 2

Studies of Elevated Parathyroid Activity

NCT00001277

COMPLETED

Studies of Inherited Diseases of Metabolism

NCT00001345

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Phase Distribution

PhaseTrial count
Phase 1 42
Phase 2 136
Phase 3 55
Phase 4 14

What is open in the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) pipeline

50 recruiting of 490 indexed (10% open); 398 completed (81%).

Phase mix: 69 late (III/IV) vs 178 early (I/II) (early-phase heavy).

Top condition: Obesity (25 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK): open-pipeline peers nationwide

Peers matched on 490 registered trials and 10% open enrollment, not the therapeutic-area sidebar.

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0200400600 8%10%12%14%16%18% Total trials Recruiting share National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)Beth Israel Deaconess Medical CenterFred Hutchinson Cancer CenterNational Heart, Lung, and Blood Institute (NHLBI)H. Lee Moffitt Cancer Center and Research InstituteMirati TherapeuticsJames J. Peters Veterans Affairs Medical CenterCalifornia Pacific Medical Center Research InstituteNational Institute of Environmental Health Sciences (NIEHS)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 490 trials (± recruiting share)

Sponsors near 10% open enrollment (± trial volume)

What to do with this National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) page

490 registered trials is a research-attention snapshot, not an endorsement of National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) or any single study.

  • 50 of National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)'s trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Obesity is the condition National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Obesity trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) pipeline card: 490 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.