National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

490 total trials 50 currently recruiting 398 completed

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) sponsors 490 registered US clinical trials on ClinicalTrials.gov, 50 of them currently recruiting, and 398 completed. 69 of these trials are in Phase 3-4 (later-stage) and 178 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Obesity, with 25 trials.

Trial Pipeline

490 total, page 8 of 10

COMPLETED Phase 2

Leptin to Treat Lipodystrophy

NCT00025883

COMPLETED NA

Motivations for Weight Loss

NCT00011115

COMPLETED

Genetic Analysis of Familial Keloids

NCT00008502

COMPLETED Phase 2

Lamivudine and Adefovir to Treat Chronic Hepatitis B

NCT00023309

COMPLETED Phase 2

Pegylated Interferon to Treat Chronic Hepatitis D

NCT00023322

COMPLETED Phase 3

Diabetes Therapy to Improve BMI and Lung Function in CF

NCT00072904

COMPLETED

Prevention of Recurrent Hepatitis B After Liver Transplantation

NCT00059267

COMPLETED Phase 2

Treatment of Nonalcoholic Steatohepatitis With Pioglitazone

NCT00013598

COMPLETED NA

Prevention of Weight Gain

NCT00011102

COMPLETED Phase 2

Kidney Transplant for HIV-Infected Patients in Renal Failure

NCT00009009

COMPLETED Phase 1

Permeability Factor in Focal Segmental Glomerulosclerosis

NCT00007475

COMPLETED Phase 2

Solitary Islet Transplantation for Type 1 Diabetes Mellitus Using Steroid Sparing Immunosuppression

NCT00006505

COMPLETED Phase 3

Gabapentin to Treat Itch in Patients With Liver Disease

NCT00058890

COMPLETED Phase 4

A Study to Determine How and Why HIV-Infected Subjects on Anti-viral Treatment Develop Lipodystrophy

NCT00006190

COMPLETED NA

Randomized Trial of Health Events Costs in Diabetic Blacks

NCT00022750

COMPLETED

Immune Response to Hepatitis C Virus

NCT00006301

COMPLETED Phase 2

Oxidative Stress and Vitamin E Requirements

NCT00067899

COMPLETED Phase 3

Vitamin K and Bone Turnover in Postmenopausal Women

NCT00062595

COMPLETED NA

The Use of the Internet to Facilitate Weight Loss and Maintenance.

NCT00008827

COMPLETED NA

Differential Metabolism of Dietary Fatty Acids

NCT00059254

COMPLETED Phase 2

Sirolimus and Thymoglobulin to Prevent Kidney Transplant Rejection

NCT00006178

COMPLETED Phase 2

Islet Cell Transplantation Alone in Patients With Type I Diabetes Mellitus: Steroid-free Immunosuppression

NCT00021788

TERMINATED

Search for New Methods to Detect Acute Renal Failure

NCT00026702

COMPLETED

Evaluation of New Test Method to Measure Kidney Function

NCT00026715

COMPLETED Phase 3

Long Term Interferon for Patients Who Did Not Clear Hepatitis C Virus With Standard Treatment

NCT00006164

COMPLETED NA

Laparoscopy to Remove Pancreatic Tumors (Insulinomas)

NCT00005910

COMPLETED Phase 2

5-Azacytidine and Phenylbutyrate to Treat Severe Thalassemia

NCT00005934

COMPLETED Phase 2

Leptin to Treat Lipodystrophy

NCT00005905

COMPLETED

Genetics of Hepatitis C Virus Infection

NCT00005657

COMPLETED NA

Altered Calcium and Vitamin D in PMDD or Severe PMS

NCT00005119

COMPLETED Phase 2

NEW DAY: Nutrition, Exercise, Weight Loss, Diabetes And You

NCT00007800

COMPLETED NA

Physical Activity in the Treatment of Obesity

NCT00615238

COMPLETED

Energy Homeostasis in Anorexia Nervosa

NCT00368667

COMPLETED Phase 2

Islet Cell Transplantation Alone and CD34+ Enriched Bone Marrow Cell Infusion in Patients With Diabetes Mellitus: Steroid-Free Regimen

NCT00021801

COMPLETED Phase 2

Once-A-Month Steroid Treatment for Patients With Focal Segmental Glomerulosclerosis

NCT00004990

COMPLETED Phase 1

A Phase I/II Trial of Recombinant-Methionyl Human Stem Cell Factor (SCF) in Adult Patients With Sickling Disorders

NCT00005783

COMPLETED Phase 2

A Study of the Safety and Efficacy of Tobramycin for Inhalation in Young Children With Cystic Fibrosis

NCT00006280

COMPLETED

Food Intake and Appetite in the Children of Mothers With Diabetes

NCT00339313

COMPLETED NA

Glomerular Injury of Preeclampsia

NCT00275158

COMPLETED NA

Evaluating "Health at Every Size"(HAES) as an Alternative Obesity Treatment Model

NCT00074633

COMPLETED Phase 3

Mobilization and Handling of Stem Cells for Transplant From Healthy Volunteers With Sickle Cell Trait

NCT00005782

COMPLETED

Genetic Influence on Susceptibility to Type 1 Diabetes Mellitus

NCT00001985

COMPLETED Phase 2

Hydroxyurea to Treat Beta-Thalassemia (Cooley's Anemia)

NCT00001958

COMPLETED Phase 2

Pirfenidone to Treat Kidney Disease (Focal Segmental Glomerulosclerosis)

NCT00001959

COMPLETED

The Food Intake Phenotype: Assessing Eating Behavior and Food Preferences as Risk Factors for Obesity

NCT00342732

COMPLETED Phase 2

Effectiveness of the Investigational Drug Campath-1H in Preventing Rejection of Transplanted Kidneys

NCT00001984

COMPLETED

The Family Investigation of Nephropathy and Diabetes Study

NCT00301249

COMPLETED NA

Education and Group Support for Diabetic Hispanics

NCT00004983

COMPLETED Phase 1

Stem Cell (Modified Bone Marrow) Transplantation in HIV-Infected Patients With Blood Cancer

NCT00005785

COMPLETED NA

Biofeedback for Dyssynergic Constipation

NCT00127257

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Phase Distribution

PhaseTrial count
Phase 1 42
Phase 2 136
Phase 3 55
Phase 4 14

What the Pipeline for National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Shows

According to the ClinicalTrials.gov registry, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) is linked to 490 US clinical trials across every stage of research activity. Of those, 50 studies are currently recruiting, about 10% of the sponsor's indexed portfolio, and 398 are already marked complete, representing roughly 81% of the total.

The phase mix for National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) reports 69 late-stage studies (Phase 3 and Phase 4 combined) and 178 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) is Obesity with 25 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.