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NCT00004285 · ClinicalTrials.gov registry record · NA

Effect of Dialysis Dose and Membrane Flux in Maintenance Hemodialysis

A NA study, sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).

Completed
Registry status
NA
Development phase
1,846
Enrollment target

NCT00004285: Completed NA study, sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).

NCT00004285 is a NA study that has completed, run by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). The registered enrollment target is 1,846 participants, above the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (31% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00004285, a NA study, has completed, sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).

COMPLETED
Registry status
NA
Development phase
1,846 participants
Enrollment target

Study Summary

OBJECTIVES: I. Evaluate whether hemodialysis providing a 2-pool, variable volume urea kinetic modelling value of 1.05 versus 1.45 reduces mortality and morbidity in patients with end stage renal disease. II. Compare the efficacy of high versus low flux dialyzer membranes.

Interventions

  • DEVICE Standard dose, low flux hemodialysis
  • DEVICE Standard dose, high flux hemodialysis
  • DEVICE High dose, low flux hemodialysis
  • DEVICE High dose, high flux hemodialysis

Trial Details

FieldValue
Enrollment Target 1,846 participants
Start Date 1995-03
Est. Completion 2001-12-31
Phase NA

What the finished NCT00004285 record still lists

NCT00004285 is an interventional study that assigns participants to a tested intervention. Its 1,846 participants enrollment target places it among the larger protocols in the corpus, above the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (31% higher).

The record links to 0 conditions, and to 4 interventions - of which Standard dose, low flux hemodialysis is the first listed.

NCT00004285 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00004285 about?

NCT00004285 is a clinical study titled "Effect of Dialysis Dose and Membrane Flux in Maintenance Hemodialysis". OBJECTIVES: I. Evaluate whether hemodialysis providing a 2-pool, variable volume urea kinetic modelling value of 1.05 versus 1.45 reduces mortality and morbidity in patients with end stage renal disease. II. Compare the efficacy of high versus low flux dialyzer membranes.

What is the current status of trial NCT00004285?

This trial is currently completed. It is a NA study. The enrollment target is 1,846 participants. The study started on 1995-03. Estimated completion is 2001-12-31.

What interventions are being tested in trial NCT00004285?

The interventions under investigation include: Standard dose, low flux hemodialysis (DEVICE), Standard dose, high flux hemodialysis (DEVICE), High dose, low flux hemodialysis (DEVICE), High dose, high flux hemodialysis (DEVICE).

Who is sponsoring clinical trial NCT00004285?

This trial is sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), which has 490 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00004285's enrollment target sits among peer trials

1,846 57th of 2000 higher than 1,944 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00004285, the US trial registry maintained by the National Library of Medicine. NCT00004285 (large enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.