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NCT00004467 · ClinicalTrials.gov registry record · Phase 3

Randomized Study of Acetylcysteine in Patients With Acute Liver Failure Not Caused by Acetaminophen

A Phase 3 study of Acute Liver Failure, sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).

Completed
Registry status
Phase 3
Development phase
173
Enrollment target
20
Study locations

NCT00004467 is a Phase 3 study of Acute Liver Failure that has completed, run by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). The registered enrollment target is 173 participants. The trial reports 20 study locations across 14 states.

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The verdict

NCT00004467, a Phase 3 study of Acute Liver Failure, has completed, sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).

COMPLETED
Registry status
Phase 3
Development phase
173 participants
Enrollment target
20
Study locations

Study Summary

OBJECTIVES: I. Determine the safety and efficacy of a short course (72 hours) of intravenous acetylcysteine in patients with acute liver failure for whom no antidote or specific treatment is available.

Conditions Studied

Interventions

  • DRUG Placebo
  • DRUG N-acetylcysteine (NAC)

Study Locations (20)

California

  • University of California Los Angeles - Los Angeles
  • University of California Davis - Sacramento
  • University of California San Diego - San Diego
  • University of California San Francisco - San Francisco

Pennsylvania

  • University of Pennsylvania - Philadelphia
  • Albert Einstein Medical Center - Philadelphia
  • University of Pittsburgh Medical Center - Pittsburgh

New York

  • Mount Sinai Medical Center, NY - New York
  • New York Presbyterian Hospital - New York

Alabama

  • University of Alabama at Birmingham - Birmingham

Arizona

  • Mayo Clinic - Scottsdale

Florida

  • Mayo Clinic - Jacksonville

Illinois

  • Northwestern University Medical School - Chicago

Massachusetts

  • Massachusetts General Hospital - Boston

Trial Details

FieldValue
Enrollment Target 173 participants
Start Date 1998-06
Est. Completion 2006-11
Phase Phase 3

What the Registry Record Tells You About NCT00004467

The ClinicalTrials.gov registry entry for NCT00004467 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 173 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), which has 490 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Acute Liver Failure appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT00004467 reports 20 study locations spanning 14 distinct geographic areas - top geographies include California, Pennsylvania, New York.

Frequently Asked Questions

What is clinical trial NCT00004467 about?

NCT00004467 is a clinical study titled "Randomized Study of Acetylcysteine in Patients With Acute Liver Failure Not Caused by Acetaminophen". OBJECTIVES: I. Determine the safety and efficacy of a short course (72 hours) of intravenous acetylcysteine in patients with acute liver failure for whom no antidote or specific treatment is available.

What is the current status of trial NCT00004467?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 173 participants. The study started on 1998-06. Estimated completion is 2006-11.

What conditions does trial NCT00004467 study?

This clinical trial studies the following conditions: Acute Liver Failure.

What interventions are being tested in trial NCT00004467?

The interventions under investigation include: Placebo (DRUG), N-acetylcysteine (NAC) (DRUG).

Who is sponsoring clinical trial NCT00004467?

This trial is sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), which has 490 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00004467 being conducted?

This trial has 20 study locations across Alabama, Arizona, California, Florida, Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.