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COMPLETED Phase 3

Diabetes Therapy to Improve BMI and Lung Function in CF

NCT00072904 · View on ClinicalTrials.gov ↗

Study Summary

To recruit 150 adult patients with cystic fibrosis related diabetes (CFRD) without fasting hyperglycemia for a multi-center, twelve month, placebo-controlled intervention trial testing the ability of insulin or repaglinide to improve body mass index (BMI) and stabilize pulmonary function in cystic fibrosis (CF).

Interventions

  • DRUG Repaglinide
  • DRUG Insulin Asparte

Study Locations (7)

California

  • Stanford University — Palo Alto

Massachusetts

  • Baystate Medical Center — Springfield

Minnesota

  • University of Minnesota Medical Center — Minneapolis

Pennsylvania

  • Children's Hospital of Pittsburgh — Pittsburgh

Tennessee

  • Vanderbilt University Medical Center — Nashville

Utah

  • University of Utah — Salt Lake City

Ontario

  • St. Michael's Hospital — Toronto

Trial Details

FieldValue
Enrollment Target 108 participants
Start Date 2001-06
Est. Completion 2007-12
Phase Phase 3

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT00072904

The ClinicalTrials.gov registry entry for NCT00072904 describes a study currently listed as completed. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 108 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), which has 375 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 2 conditions, with Diabetes Mellitus appearing as the primary indexed condition, and to 2 interventions — of which Repaglinide is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT00072904 reports 7 study locations spanning 7 distinct geographic areas — top geographies include California, Massachusetts, Minnesota. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT00072904 about?

NCT00072904 is a clinical study titled "Diabetes Therapy to Improve BMI and Lung Function in CF". To recruit 150 adult patients with cystic fibrosis related diabetes (CFRD) without fasting hyperglycemia for a multi-center, twelve month, placebo-controlled intervention trial testing the ability of insulin or repaglinide to improve body mass index (BMI) and stabilize pulmonary function in cystic f...

What is the current status of trial NCT00072904?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 108 participants. The study started on 2001-06. Estimated completion is 2007-12.

What conditions does trial NCT00072904 study?

This clinical trial studies the following conditions: Diabetes Mellitus, Cystic Fibrosis. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT00072904?

The interventions under investigation include: Repaglinide (DRUG), Insulin Asparte (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT00072904?

This trial is sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), which has 375 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT00072904 being conducted?

This trial has 7 study locations across California, Massachusetts, Minnesota, Pennsylvania, Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial