Johns Hopkins University

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Johns Hopkins University sits in the top decile of US sponsors by registered trial count (#14 of 15,742 sponsors by registered trial count).

1,448 total trials 250 currently recruiting 943 completed early-phase tilt top decile by trial count

Johns Hopkins University: 1,448 sponsored US clinical trials, 250 recruiting.

Johns Hopkins University sponsors 1,448 registered US clinical trials on ClinicalTrials.gov, 250 of them currently recruiting, and 943 completed. 125 of these trials are in Phase 3-4 (later-stage) and 399 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Hypertension, with 15 trials.

Top-decile sponsor footprint

Johns Hopkins University ranks in the top decile of sponsors by registered trial count (#14 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 52/100

943 of 1,108 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (85.1%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

1,448 total, page 28 of 29

TERMINATED

Structuring the Integration of Care Management Services For Medicaid Enrollees Recipients With Chronic Illness, Substance Abuse Problems and Possible Psychiatric Disorders

NCT00399373

COMPLETED Phase 2

Treating the Partners of Drug Using Pregnant Women: Stage II

NCT00496990

COMPLETED

Umbilical Cord Blood Proteomic Analysis and Neonatal Brain Injury

NCT00375908

COMPLETED

Health Outcomes in Rheumatoid Arthritis

NCT00346411

COMPLETED

The Effects of Methadone and Buprenorphine on Fetal Neurobehavior and Infant Neonatal Abstinence Syndrome - 1

NCT00218621

COMPLETED Phase 1

Atkins Diet for Difficult-to-Control Headaches in Teenagers

NCT00181064

TERMINATED NA

Anterior Pituitary Function in Patients With Hydrocephalus

NCT00149721

TERMINATED Phase 2

Macrolides to Prevent Exacerbations of Asthma and Chronic Obstructive Pulmonary Disease

NCT00181272

COMPLETED Phase 2

Cyclophosphamide in Treating Young Patients With Severe Autoimmune Enteropathy

NCT00258180

COMPLETED NA

Coronary Atherosclerosis Evaluation by Arterial Wall Magnetic Resonance Imaging (MRI)

NCT00353795

COMPLETED Phase 3

RCT Comparing Methadone and Buprenorphine in Pregnant Women

NCT00271219

COMPLETED Phase 4

Effect of Soy on Cognition and Hot Flashes in Men With Prostate Cancer Undergoing Testosterone Suppression Therapy

NCT00245518

COMPLETED Phase 2

Acute Neurological ICU Sedation Trial (ANIST)

NCT00390871

COMPLETED

Reducing Asthma Disparities by Improving Provider-Patient Communication

NCT00181194

TERMINATED Phase 2

Effect of Anti-IgE in Non-Allergic Asthma

NCT00162773

COMPLETED Phase 4

Levetiracetam for Benign Rolandic Epilepsy

NCT00181116

COMPLETED

Study of the Implantable Cardioverter Defibrillator (ICD) Intracardiac Electrograms

NCT00916435

COMPLETED Phase 1

Use of the Atkins Diet for Children With Intractable Epilepsy: A Comparison of Daily Carbohydrate Limits

NCT00181090

COMPLETED NA

Treatment of Executive Dysfunction in Parkinson's Disease

NCT00286949

COMPLETED NA

Post-Operative Delirium in Elderly Surgical Patients

NCT00590707

COMPLETED NA

Depression Prevention Program for American Indian Adolescents During and After Pregnancy

NCT00183547

COMPLETED Phase 2

Tobacco Use in Opioid Agonist Treated Pregnant Women

NCT00497068

COMPLETED

Redistribution of Fat and Metabolic Change in HIV Infection: Protocol 2 (FRAM Fat 2)

NCT00244803

COMPLETED Phase 3

Job-Seekers Training for Patients With Drug Dependence - 1

NCT00102362

COMPLETED Phase 2

Effect of Anti-IgE in Chronic Urticaria

NCT00130234

COMPLETED Phase 2

Intravenous Allopurinol in Heart Failure

NCT00181155

COMPLETED Phase 2

Recovery Housing For Drug Dependent Pregnant Women

NCT00497302

COMPLETED

Long-Term Results in Mechanically Ventilated Individuals With Acute Lung Injury/Acute Respiratory Distress Syndrome

NCT00300248

COMPLETED

Diffusion-Tensor Magnetic Resonance Imaging (MRI) and the Evaluation of Perinatal Brain Injury

NCT00131859

COMPLETED Phase 2

Evaluating Patient Information Prescriptions

NCT00355381

COMPLETED NA

Intervention for Improving Asthma Care for Minority Children in Head Start

NCT00094276

COMPLETED

Effects of Endocrine Health on Mental Performance of Men and Women Using Drugs

NCT00245531

COMPLETED Phase 3

Nature Sights and Sounds to Reduce Pain in Cancer Patients Undergoing Bone Marrow Aspiration and Biopsy

NCT00315796

COMPLETED

Trans Nasal Insufflation for the Treatment of Snoring

NCT00832026

COMPLETED Phase 2

Depression in Alzheimer's Disease-2

NCT00086138

COMPLETED NA

Problem Solving and Cardiovascular Disease Risk Management in Diabetic Blacks

NCT00201110

COMPLETED NA

Use of the Atkins Diet for Adults With Intractable Epilepsy

NCT00121927

COMPLETED Phase 4

Airway Clearance for Prevention of Chronic Obstructive Pulmonary Disease (COPD) Exacerbation

NCT00181207

COMPLETED Phase 2

A Double-Blind Placebo Controlled Trial of Riluzole in Bipolar Depression

NCT00376220

COMPLETED Phase 4

Mucociliary Clearance in Healthy Subjects: Comparison of Levalbuterol and Racemic Albuterol

NCT00325767

COMPLETED Phase 2

Optimal Dose of Prophylactic Naloxone in Reducing Opioid-Induced Side Effects in Children/Adolescents

NCT00330343

COMPLETED Phase 2

Clinical Trial on Treatment of Intraventricular Hemorrhage

NCT00650858

COMPLETED NA

Improving Delivery of Mental Health Services for Patients With Drug Use and Other Behavioral and Emotional Problems

NCT00787735

COMPLETED NA

Effectiveness of Home Automated Telemanagement in Chronic Obstructive Pulmonary Disorder

NCT00752531

COMPLETED NA

Employment-based Reinforcement to Motivate Drug Abstinence in the Treatment of Drug Addiction. - 1

NCT00249496

COMPLETED Phase 2

Treatment of Idiopathic Pulmonary Fibrosis With Thalidomide

NCT00162760

COMPLETED Phase 3

High-Density Lipoprotein (HDL) Cholesterol Increased Plaque Stabilization in the Elderly

NCT00127218

COMPLETED NA

Intervention Study to Control High Blood Pressure for Korean American

NCT00473681

COMPLETED NA

Improving Provider Counseling Interventions in HIV Practice

NCT00538993

COMPLETED NA

Family-Based Prevention Program for Childhood Anxiety

NCT00078728

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Phase Distribution

PhaseTrial count
Phase 1 201
Phase 2 198
Phase 3 44
Phase 4 81

What is open in the Johns Hopkins University pipeline

250 recruiting of 1,448 indexed (17% open); 943 completed (65%).

Phase mix: 125 late (III/IV) vs 399 early (I/II) (early-phase heavy).

Top condition: Hypertension (15 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Johns Hopkins University: open-pipeline peers nationwide

Peers matched on 1,448 registered trials and 17% open enrollment, not the therapeutic-area sidebar.

Johns Hopkins University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,5002,000 5%10%15%20% Total trials Recruiting share Johns Hopkins UniversityUniversity of PennsylvaniaYale UniversityWashington University School of MedicineNovartis PharmaceuticalsSeattle Children's HospitalHunter College of City University of New YorkOchsner Health SystemVirginia Polytechnic Institute and State University
Johns Hopkins University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Johns Hopkins University sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 1,448 trials (± recruiting share)

Sponsors near 17% open enrollment (± trial volume)

What to do with this Johns Hopkins University page

1,448 registered trials is a research-attention snapshot, not an endorsement of Johns Hopkins University or any single study.

  • 250 of Johns Hopkins University's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Hypertension is the condition Johns Hopkins University studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Hypertension trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Johns Hopkins University pipeline card: 1,448 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.