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NCT00375908 · ClinicalTrials.gov registry record
Umbilical Cord Blood Proteomic Analysis and Neonatal Brain Injury
A clinical trial, sponsored by Johns Hopkins University.
- Completed
- Registry status
- 4
- Enrollment target
NCT00375908: Completed study, sponsored by Johns Hopkins University.
NCT00375908 is a clinical trial that has completed, run by Johns Hopkins University. The registered enrollment target is 4 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00375908 has completed, sponsored by Johns Hopkins University.
- COMPLETED
- Registry status
- 4 participants
- Enrollment target
Study Summary
The investigators propose to compare the proteomic analysis of umbilical venous blood from neonates with brain injury to gestational age matched noninjured controls. After delivery an umbilical arterial gas and a 10 ml umbilical venous sample are obtained, then the remainder of the cord blood is discarded. The investigators plan to use this cord blood that would otherwise be discarded to perform our proteomic analysis. The investigators will use up to 20 ml of cord blood per delivery. This will be a 5 year study during which time the investigators hope to analyze 450 infants at Johns Hopkins Hospital and Bayview Medical Center. The investigators will obtain an umbilical venous sample from infants born at \< 34 weeks gestation. For infants born at \> 34 weeks the investigators will obtain an umbilical venous sample for any infant suspected to be at risk for neurologic injury by having a diagnosis of chorioamnionitis during labor, nonreassuring fetal heart rate tracing at the time of delivery, or a 5 minute Apgar \< 7. For the infants born at \< 34 weeks the brain injured infants will be compared to gestational age matched controls without brain injury. For the infants born at \> 34 weeks, each infant later confirmed to have neurologic morbidity will be compared to a gestational age matched noninjured control. The investigators hope to use proteomic analysis to determine if there are measurable differences in protein expression between the 2 groups.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 4 participants |
| Start Date | 2005-10 |
| Est. Completion | 2008-12 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00375908
The ClinicalTrials.gov registry entry for NCT00375908 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 4 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Johns Hopkins University, which has 1,448 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 0 interventions.
NCT00375908 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT00375908 about?
NCT00375908 is a clinical study titled "Umbilical Cord Blood Proteomic Analysis and Neonatal Brain Injury". The investigators propose to compare the proteomic analysis of umbilical venous blood from neonates with brain injury to gestational age matched noninjured controls. After delivery an umbilical arterial gas and a 10 ml umbilical venous sample are obtained, then the remainder of the cord blood is dis...
What is the current status of trial NCT00375908?
This trial is currently completed. The enrollment target is 4 participants. The study started on 2005-10. Estimated completion is 2008-12.
Who is sponsoring clinical trial NCT00375908?
This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.
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