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NCT00181272 · ClinicalTrials.gov registry record · Phase 2
Macrolides to Prevent Exacerbations of Asthma and Chronic Obstructive Pulmonary Disease
A Phase 2 study, sponsored by Johns Hopkins University.
- Terminated
- Registry status
- Phase 2
- Development phase
- 18
- Enrollment target
NCT00181272: Clinical Trial Phase 2 study, sponsored by Johns Hopkins University.
NCT00181272 is a Phase 2 study that was terminated before completion, run by Johns Hopkins University. The registered enrollment target is 18 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (86% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00181272, a Phase 2 study, was terminated before completion, sponsored by Johns Hopkins University.
- TERMINATED
- Registry status
- Phase 2
- Development phase
- 18 participants
- Enrollment target
Study Summary
The purpose of this study is to determine whether macrolide therapy is effective in treating patients hospitalized with asthma exacerbations or chronic obstructive pulmonary disease (COPD)exacerbations. We hypothesize that compared to placebo, maintenance therapy with macrolides, when added to usual care, a) improves respiratory symptoms, b) improves quality of life, c) reduces airway inflammation, d) reduces airflow obstruction, and e) decreases the rate of re-exacerbations.
Interventions
- DRUG azithromycin
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 18 participants |
| Start Date | 2005-09 |
| Est. Completion | 2006-07 |
| Phase | Phase 2 |
Why NCT00181272 stopped before completion
NCT00181272 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 18 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (86% lower).
The record links to 0 conditions, and to 1 intervention - of which azithromycin is the first listed.
NCT00181272 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00181272 about?
NCT00181272 is a clinical study titled "Macrolides to Prevent Exacerbations of Asthma and Chronic Obstructive Pulmonary Disease". The purpose of this study is to determine whether macrolide therapy is effective in treating patients hospitalized with asthma exacerbations or chronic obstructive pulmonary disease (COPD)exacerbations. We hypothesize that compared to placebo, maintenance therapy with macrolides, when added to usual...
What is the current status of trial NCT00181272?
This trial is currently terminated. It is a Phase 2 study. The enrollment target is 18 participants. The study started on 2005-09. Estimated completion is 2006-07.
What interventions are being tested in trial NCT00181272?
The interventions under investigation include: azithromycin (DRUG).
Who is sponsoring clinical trial NCT00181272?
This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00181272's enrollment target sits among peer trials
18 1898th of 2000 higher than 98 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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