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NCT00181207 · ClinicalTrials.gov registry record · Phase 4
Airway Clearance for Prevention of Chronic Obstructive Pulmonary Disease (COPD) Exacerbation
A Phase 4 study of COPD and Emphysema, sponsored by Johns Hopkins University.
- Completed
- Registry status
- Phase 4
- Development phase
- 50
- Enrollment target
- 1
- Study location
NCT00181207: Completed Phase 4 study of COPD and Emphysema, sponsored by Johns Hopkins University.
NCT00181207 is a Phase 4 study of COPD and Emphysema that has completed, run by Johns Hopkins University. The registered enrollment target is 50 participants, below the 2,418-participant average among 85 other COPD trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00181207, a Phase 4 study of COPD and Emphysema, has completed, sponsored by Johns Hopkins University.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 50 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to show that one form of mechanical airway clearance techniques, High Frequency Chest Wall Oscillation (HFCWO)using a pneumatic vest, will diminish exacerbations of COPD which will improve respiratory health status.
Primary Outcome
count of exacerbations per group per 12 weeks. An exacerbation was defined based on three major symptoms: increasing dyspnea, increasing sputum purulence and increasing sputum volume. Exacerbations were counted if there were at least 2 of these 3 symptoms.
Conditions Studied
Interventions
- DEVICE pneumatic vest
- OTHER placebo pneumatic vest
Study Locations (1)
Maryland
- Johns Hopkins Asthma and Allergy Center - Baltimore
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2004-05 |
| Est. Completion | 2007-12 |
| Phase | Phase 4 |
What the finished NCT00181207 record still lists
NCT00181207 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 2,418-participant average among 85 other COPD trials with a reported enrollment target (98% lower).
The record links to 3 conditions, with COPD appearing as the primary indexed condition, and to 2 interventions - of which pneumatic vest is the first listed.
NCT00181207 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT00181207 about?
NCT00181207 is a clinical study titled "Airway Clearance for Prevention of Chronic Obstructive Pulmonary Disease (COPD) Exacerbation". The purpose of this study is to show that one form of mechanical airway clearance techniques, High Frequency Chest Wall Oscillation (HFCWO)using a pneumatic vest, will diminish exacerbations of COPD which will improve respiratory health status.
What is the current status of trial NCT00181207?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 50 participants. The study started on 2004-05. Estimated completion is 2007-12.
What conditions does trial NCT00181207 study?
This clinical trial studies the following conditions: COPD, Emphysema, Chronic Bronchitis.
What interventions are being tested in trial NCT00181207?
The interventions under investigation include: pneumatic vest (DEVICE), placebo pneumatic vest (OTHER).
Who is sponsoring clinical trial NCT00181207?
This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00181207 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for COPD
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00181207's enrollment target sits among peer trials
50 52nd of 85 higher than 33 of 85 other COPD trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other COPD trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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