Seattle Children's Hospital

127 total trials 82 currently recruiting 28 completed

Trial Pipeline

RECRUITING Phase 1

Immunotherapy for Solid Tumor Malignancies in Pediatrics Using Interleukin-15 and -21 Armored Glypican-3-specific Chimeric Antigen Receptor T Cells

NCT07148050

RECRUITING NA

I-DECIDE After Bronchiolitis Hospitalization

NCT07243652

RECRUITING NA

Concussion Recovery and Support Program

NCT07097792

RECRUITING NA

Comparative Efficacy of Organizational Skills Training (OST) and Mindfulness-Based Intervention (MBI)

NCT07281092

RECRUITING NA

Effects of High-Resistance Inspiratory Muscle Strength Training on Cardiorenal and Vascular Function in Youth and Young Adults With Type 2 Diabetes

NCT06936670

RECRUITING Phase 2

Efficacy and Safety of Phentermine/Topiramate in Youth With Hypothalamic Obesity

NCT06299891

RECRUITING Phase 2

The "What Is Important to Us" Communication Intervention Pilot Clinical Trial

NCT06208332

RECRUITING Phase 1

REACT-01: Reversing Autoimmunity Through Cell Therapy

NCT06465147

RECRUITING

Using Ecological Momentary Assessment to Develop an Adaptive Psychological Intervention for Young Adults With Chronic Pain

NCT06932432

RECRUITING NA

Pilot Trial of the RUBI Program for Autistic Adults

NCT06593613

RECRUITING NA

The PRISM-Social Needs (PRISM-SN) Intervention for Adolescents and Young Adults With Cancer

NCT06242964

RECRUITING

Seattle Spatial Transcriptomic Research in Inflammatory Bowel Disease Evaluation (STRIDE)

NCT06315179

RECRUITING NA

Internet-Delivered Pain Self-Management for Persons With Acute Recurrent and Chronic Pancreatitis Pain

NCT06386224

RECRUITING NA

Reverse-Engineering of Exclusive Enteral Nutrition (RE-EEN) in Crohn's Disease: A Multi-Center Trial

NCT06216899

RECRUITING NA

Concussion Health Improvement Program

NCT06036147

RECRUITING NA

Online Social Learning Program for Parents With Irritable Bowel Syndrome: Raising Resilient Children

NCT05730491

RECRUITING NA

Resilience Mobile App for Teens and Young Adults With Cancer

NCT05842902

RECRUITING NA

Comparing Two Models of Well-Child Care for Black Families

NCT05852392

RECRUITING NA

Advancing Suicide Intervention Strategies for Teens During High Risk Periods

NCT05078970

RECRUITING NA

A Comprehensive Trauma-sensitive Approach to Physical Activity Promotion in Schools (CSPAP-T)

NCT05382975

RECRUITING NA

Using Shared Decision Making to Improve Family Media Use Planning

NCT05722535

RECRUITING NA

Brain Injury Education and Outpatient Navigation-1stBIEN

NCT05261477

RECRUITING Phase 1

PLAT-08: A Study Of SC-DARIC33 CAR T Cells In Pediatric And Young Adults With Relapsed Or Refractory CD33+ AML

NCT05105152

RECRUITING

Laser Photocoagulation of Communicating Vessels in Twin-to-Twin Transfusion Syndrome

NCT05008744

RECRUITING Phase 1

Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors

NCT04185038

RECRUITING

CHronic Nonbacterial Osteomyelitis International Registry

NCT04725422

RECRUITING Phase 1

Fecal Microbiota Transplantation as a Strategy to Eradicate Resistant Organisms

NCT02543866

ACTIVE NOT RECRUITING Phase 1

Study of B7-H3, EGFR806, HER2, And IL13-Zetakine (Quad) CAR T Cell Locoregional Immunotherapy For Pediatric Diffuse Intrinsic Pontine Glioma, Diffuse Midline Glioma, And Recurrent Or Refractory Central Nervous System Tumors

NCT05768880

ACTIVE NOT RECRUITING NA

Mobile Video Interpretation to Optimize Communication Across Language Barriers

NCT05591586

ACTIVE NOT RECRUITING Phase 1

A Phase I Feasibility And Safety Study of Fluorescein-Specific (FITC-E2) CAR T Cells In Combination With Parenterally Administered Folate-Fluorescein (UB-TT170) For Osteogenic Sarcoma

NCT05312411

ACTIVE NOT RECRUITING NA

Intervention for Sleep and Pain in Youth: a Randomized Controlled Trial

NCT04936321

ACTIVE NOT RECRUITING NA

Mobile Subthreshold Exercise Program for Concussion--R01

NCT04688255

ACTIVE NOT RECRUITING Phase 3

Brain Activation and Satiety in Children 2

NCT04520490

ACTIVE NOT RECRUITING Phase 1

A Pediatric and Young Adult Trial of Genetically Modified T Cells Directed Against CD22 for Relapsed/Refractory Leukemia or Lymphoma

NCT04571138

ACTIVE NOT RECRUITING Phase 1

B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

NCT04483778

ACTIVE NOT RECRUITING Phase 1

EGFR806 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

NCT03618381

ACTIVE NOT RECRUITING Phase 1

CD19-specific CAR T Cells With a Fully Human Binding Domain for CD19+ Leukemia or Lymphoma

NCT03684889

ACTIVE NOT RECRUITING Phase 1

HER2-specific CAR T Cell Locoregional Immunotherapy for HER2-positive Recurrent/Refractory Pediatric CNS Tumors

NCT03500991

ACTIVE NOT RECRUITING Phase 1

A Feasibility and Safety Study of Dual Specificity CD19 and CD22 CAR-T Cell Immunotherapy for CD19+CD22+ Leukemia

NCT03330691

ACTIVE NOT RECRUITING Phase 1

Pilot Study of T-APCs Following CAR T Cell Immunotherapy for CD19+ Leukemia

NCT03186118

ACTIVE NOT RECRUITING Phase 1

A Phase 1 Study of CD22-CAR TCell Immunotherapy for CD22+ Leukemia and Lymphoma

NCT03244306

ACTIVE NOT RECRUITING Phase 1

Engineered Neuroblastoma Cellular Immunotherapy (ENCIT)-01

NCT02311621

ACTIVE NOT RECRUITING Phase 1

A Pediatric and Young Adult Trial of Genetically Modified T Cells Directed Against CD19 for Relapsed/Refractory CD19+ Leukemia

NCT02028455

ACTIVE NOT RECRUITING Phase 1

A Pediatric Trial of Genetically Modified Autologous T Cells Directed Against CD19 for Relapsed CD19+ Acute Lymphoblastic Leukemia

NCT01683279

COMPLETED NA

Better Research Interactions for Every Family

NCT04152603

COMPLETED NA

Developing a Dyadic Shared Decision Making Tool About Firearm Storage

NCT05451355

COMPLETED NA

A Peer-Delivered High School Preparatory Intervention for Students With ADHD

NCT04571320

COMPLETED NA

Developing an Implementation Strategy for Post-concussion Communication With Low Health Literacy Parents in the Emergency Department

NCT04112914

COMPLETED NA

Internet Based Cognitive Behavioral Therapy in Pediatric Chronic Pancreatitis

NCT03707431

COMPLETED NA

SOFI: A Quality Improvement Project to Standardize Use of Intravenous Fluids in Hospitalized Pediatric Patients

NCT03924674

COMPLETED NA

Well-Child Care Clinical Practice Redesign: A Parent Coach-Led Model of Care

NCT03797898

COMPLETED

Gene Expression Objective Definition of Early Sepsis In Children

NCT06231862

COMPLETED NA

Cerebral Palsy: Ankle Foot Orthoses - Footwear Combinations

NCT03756571

COMPLETED NA

Mechanisms Of Change in Adolescent Pain Self-management

NCT04043962

COMPLETED NA

Fit 5 Kids Screen Time Reduction Curriculum for Latino Preschoolers

NCT03575884

COMPLETED

Craniofacial Microsomia: Accelerating Understanding of the Significance and Etiology

NCT04351893

COMPLETED NA

Internet-based Pain Self-management for Persons With Acute Recurrent and Chronic Pancreatitis Pain

NCT03322644

COMPLETED NA

Study of an Exercise Program (STEP) for Youth With Concussion

NCT02673112

COMPLETED Early Phase 1

Dexmedetomidine Pharmacokinetics in Neonates During Therapeutic Hypothermia

NCT02529202

COMPLETED NA

Text2Breathe: Enhance Parent Communication to Reduce Pediatric Asthma Disparities

NCT03032159

COMPLETED NA

Comparing Remote Interpreter Modalities in the Pediatric Emergency Department

NCT01986179

COMPLETED

Craniofacial Microsomia: Longitudinal Outcomes in Children Pre-Kindergarten (CLOCK)

NCT02224677

COMPLETED NA

Lidocaine Analgesia for Urethral Catheterization in Children

NCT01780324

COMPLETED NA

Parent Partnership Project

NCT01789944

COMPLETED NA

Evaluation of a Walking School Bus Program

NCT01626807

COMPLETED NA

Problem Solving Skills Training For Parent Caregivers of Youth With Chronic Pain

NCT01496378

COMPLETED NA

Changing Chat: Diaper Tips to Improve Language Development

NCT01594840

COMPLETED NA

Improving Care for Children With Complex Needs

NCT01587105

COMPLETED NA

Children's Attention Deficit Disorder With Hyperactivity (ADHD) Telemental Health Treatment Study

NCT00830700

COMPLETED NA

Self-Management of Cancer-Related Fatigue by Adolescents

NCT00862186

COMPLETED Phase 4

Trial of Early Aggressive Drug Therapy in Juvenile Idiopathic Arthritis

NCT00443430

COMPLETED Phase 2

Safety and Immunogenicity of Inactivated Influenza Virus Vaccine Among Healthy Children 6-12 Weeks of Age

NCT00242424

Phase Distribution

PhaseTrial count
Phase 1 46
Phase 2 3
Phase 3 1
Phase 4 1

What the Pipeline for Seattle Children's Hospital Shows

According to the ClinicalTrials.gov registry, Seattle Children's Hospital is linked to 127 US clinical trials across every stage of research activity. Of those, 82 studies are currently recruiting — about 65% of the sponsor's indexed portfolio — and 28 are already marked complete, representing roughly 22% of the total. Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

The phase mix for Seattle Children's Hospital reports 2 late-stage studies (Phase 3 and Phase 4 combined) and 49 earlier-phase studies (Phase 1 and Phase 2). A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work — safety, dosing, and early signal detection — and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

The top therapeutic focus area indexed for Seattle Children's Hospital is Germ Cell Tumor with 4 linked trials, and 9 other condition areas appear in the top list above. That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice — verify current details directly with ClinicalTrials.gov before relying on any figure here.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial