Seattle Children's Hospital
Trial Pipeline
Immunotherapy for Solid Tumor Malignancies in Pediatrics Using Interleukin-15 and -21 Armored Glypican-3-specific Chimeric Antigen Receptor T Cells
NCT07148050
I-DECIDE After Bronchiolitis Hospitalization
NCT07243652
Concussion Recovery and Support Program
NCT07097792
Comparative Efficacy of Organizational Skills Training (OST) and Mindfulness-Based Intervention (MBI)
NCT07281092
Effects of High-Resistance Inspiratory Muscle Strength Training on Cardiorenal and Vascular Function in Youth and Young Adults With Type 2 Diabetes
NCT06936670
Efficacy and Safety of Phentermine/Topiramate in Youth With Hypothalamic Obesity
NCT06299891
The "What Is Important to Us" Communication Intervention Pilot Clinical Trial
NCT06208332
REACT-01: Reversing Autoimmunity Through Cell Therapy
NCT06465147
Using Ecological Momentary Assessment to Develop an Adaptive Psychological Intervention for Young Adults With Chronic Pain
NCT06932432
Pilot Trial of the RUBI Program for Autistic Adults
NCT06593613
The PRISM-Social Needs (PRISM-SN) Intervention for Adolescents and Young Adults With Cancer
NCT06242964
Seattle Spatial Transcriptomic Research in Inflammatory Bowel Disease Evaluation (STRIDE)
NCT06315179
Internet-Delivered Pain Self-Management for Persons With Acute Recurrent and Chronic Pancreatitis Pain
NCT06386224
Reverse-Engineering of Exclusive Enteral Nutrition (RE-EEN) in Crohn's Disease: A Multi-Center Trial
NCT06216899
Concussion Health Improvement Program
NCT06036147
Online Social Learning Program for Parents With Irritable Bowel Syndrome: Raising Resilient Children
NCT05730491
Resilience Mobile App for Teens and Young Adults With Cancer
NCT05842902
Comparing Two Models of Well-Child Care for Black Families
NCT05852392
Advancing Suicide Intervention Strategies for Teens During High Risk Periods
NCT05078970
A Comprehensive Trauma-sensitive Approach to Physical Activity Promotion in Schools (CSPAP-T)
NCT05382975
Using Shared Decision Making to Improve Family Media Use Planning
NCT05722535
Brain Injury Education and Outpatient Navigation-1stBIEN
NCT05261477
PLAT-08: A Study Of SC-DARIC33 CAR T Cells In Pediatric And Young Adults With Relapsed Or Refractory CD33+ AML
NCT05105152
Laser Photocoagulation of Communicating Vessels in Twin-to-Twin Transfusion Syndrome
NCT05008744
Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors
NCT04185038
CHronic Nonbacterial Osteomyelitis International Registry
NCT04725422
Fecal Microbiota Transplantation as a Strategy to Eradicate Resistant Organisms
NCT02543866
Study of B7-H3, EGFR806, HER2, And IL13-Zetakine (Quad) CAR T Cell Locoregional Immunotherapy For Pediatric Diffuse Intrinsic Pontine Glioma, Diffuse Midline Glioma, And Recurrent Or Refractory Central Nervous System Tumors
NCT05768880
Mobile Video Interpretation to Optimize Communication Across Language Barriers
NCT05591586
A Phase I Feasibility And Safety Study of Fluorescein-Specific (FITC-E2) CAR T Cells In Combination With Parenterally Administered Folate-Fluorescein (UB-TT170) For Osteogenic Sarcoma
NCT05312411
Intervention for Sleep and Pain in Youth: a Randomized Controlled Trial
NCT04936321
Mobile Subthreshold Exercise Program for Concussion--R01
NCT04688255
Brain Activation and Satiety in Children 2
NCT04520490
A Pediatric and Young Adult Trial of Genetically Modified T Cells Directed Against CD22 for Relapsed/Refractory Leukemia or Lymphoma
NCT04571138
B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults
NCT04483778
EGFR806 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults
NCT03618381
CD19-specific CAR T Cells With a Fully Human Binding Domain for CD19+ Leukemia or Lymphoma
NCT03684889
HER2-specific CAR T Cell Locoregional Immunotherapy for HER2-positive Recurrent/Refractory Pediatric CNS Tumors
NCT03500991
A Feasibility and Safety Study of Dual Specificity CD19 and CD22 CAR-T Cell Immunotherapy for CD19+CD22+ Leukemia
NCT03330691
Pilot Study of T-APCs Following CAR T Cell Immunotherapy for CD19+ Leukemia
NCT03186118
A Phase 1 Study of CD22-CAR TCell Immunotherapy for CD22+ Leukemia and Lymphoma
NCT03244306
Engineered Neuroblastoma Cellular Immunotherapy (ENCIT)-01
NCT02311621
A Pediatric and Young Adult Trial of Genetically Modified T Cells Directed Against CD19 for Relapsed/Refractory CD19+ Leukemia
NCT02028455
A Pediatric Trial of Genetically Modified Autologous T Cells Directed Against CD19 for Relapsed CD19+ Acute Lymphoblastic Leukemia
NCT01683279
Better Research Interactions for Every Family
NCT04152603
Developing a Dyadic Shared Decision Making Tool About Firearm Storage
NCT05451355
A Peer-Delivered High School Preparatory Intervention for Students With ADHD
NCT04571320
Developing an Implementation Strategy for Post-concussion Communication With Low Health Literacy Parents in the Emergency Department
NCT04112914
Internet Based Cognitive Behavioral Therapy in Pediatric Chronic Pancreatitis
NCT03707431
SOFI: A Quality Improvement Project to Standardize Use of Intravenous Fluids in Hospitalized Pediatric Patients
NCT03924674
Well-Child Care Clinical Practice Redesign: A Parent Coach-Led Model of Care
NCT03797898
Gene Expression Objective Definition of Early Sepsis In Children
NCT06231862
Cerebral Palsy: Ankle Foot Orthoses - Footwear Combinations
NCT03756571
Mechanisms Of Change in Adolescent Pain Self-management
NCT04043962
Fit 5 Kids Screen Time Reduction Curriculum for Latino Preschoolers
NCT03575884
Craniofacial Microsomia: Accelerating Understanding of the Significance and Etiology
NCT04351893
Internet-based Pain Self-management for Persons With Acute Recurrent and Chronic Pancreatitis Pain
NCT03322644
Study of an Exercise Program (STEP) for Youth With Concussion
NCT02673112
Dexmedetomidine Pharmacokinetics in Neonates During Therapeutic Hypothermia
NCT02529202
Text2Breathe: Enhance Parent Communication to Reduce Pediatric Asthma Disparities
NCT03032159
Comparing Remote Interpreter Modalities in the Pediatric Emergency Department
NCT01986179
Craniofacial Microsomia: Longitudinal Outcomes in Children Pre-Kindergarten (CLOCK)
NCT02224677
Lidocaine Analgesia for Urethral Catheterization in Children
NCT01780324
Parent Partnership Project
NCT01789944
Evaluation of a Walking School Bus Program
NCT01626807
Problem Solving Skills Training For Parent Caregivers of Youth With Chronic Pain
NCT01496378
Changing Chat: Diaper Tips to Improve Language Development
NCT01594840
Improving Care for Children With Complex Needs
NCT01587105
Children's Attention Deficit Disorder With Hyperactivity (ADHD) Telemental Health Treatment Study
NCT00830700
Self-Management of Cancer-Related Fatigue by Adolescents
NCT00862186
Trial of Early Aggressive Drug Therapy in Juvenile Idiopathic Arthritis
NCT00443430
Safety and Immunogenicity of Inactivated Influenza Virus Vaccine Among Healthy Children 6-12 Weeks of Age
NCT00242424
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 46 |
| Phase 2 | 3 |
| Phase 3 | 1 |
| Phase 4 | 1 |
Therapeutic Areas
What the Pipeline for Seattle Children's Hospital Shows
According to the ClinicalTrials.gov registry, Seattle Children's Hospital is linked to 127 US clinical trials across every stage of research activity. Of those, 82 studies are currently recruiting — about 65% of the sponsor's indexed portfolio — and 28 are already marked complete, representing roughly 22% of the total. Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
The phase mix for Seattle Children's Hospital reports 2 late-stage studies (Phase 3 and Phase 4 combined) and 49 earlier-phase studies (Phase 1 and Phase 2). A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work — safety, dosing, and early signal detection — and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
The top therapeutic focus area indexed for Seattle Children's Hospital is Germ Cell Tumor with 4 linked trials, and 9 other condition areas appear in the top list above. That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice — verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology — how this data is sourced, computed, and verified.