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NCT00650858 · ClinicalTrials.gov registry record · Phase 2

Clinical Trial on Treatment of Intraventricular Hemorrhage

A Phase 2 study, sponsored by Johns Hopkins University.

Completed
Registry status
Phase 2
Development phase
52
Enrollment target

NCT00650858: Completed Phase 2 study, sponsored by Johns Hopkins University.

NCT00650858 is a Phase 2 study that has completed, run by Johns Hopkins University. The registered enrollment target is 52 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (61% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

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The verdict

NCT00650858, a Phase 2 study, has completed, sponsored by Johns Hopkins University.

COMPLETED
Registry status
Phase 2
Development phase
52 participants
Enrollment target

Study Summary

The specific objective of this trial is to determine the lowest dose and dose frequency possible with the best pharmacokinetic and safety profile and it's ability to remove a blood clot from the ventricular system.

Primary Outcome

The number of subjects who died at or before the 30-day follow-up visit were determined as a measure of safety. If more than 50% of the subjects died at or before the 30-day follow-up visit, the study would have been stopped for full DSMB review.

Interventions

  • DRUG tissue plasminogen activator, rt-PA (thrombolytic) (Cathflo)

Trial Details

FieldValue
Enrollment Target 52 participants
Start Date 2004-02
Est. Completion 2008-08
Phase Phase 2
Johns Hopkins University

1,448 total trials

What the finished NCT00650858 record still lists

NCT00650858 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 52 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (61% lower).

The record links to 0 conditions, and to 1 intervention - of which tissue plasminogen activator, rt-PA (thrombolytic) (Cathflo) is the first listed.

NCT00650858 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00650858 about?

NCT00650858 is a clinical study titled "Clinical Trial on Treatment of Intraventricular Hemorrhage". The specific objective of this trial is to determine the lowest dose and dose frequency possible with the best pharmacokinetic and safety profile and it's ability to remove a blood clot from the ventricular system.

What is the current status of trial NCT00650858?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 52 participants. The study started on 2004-02. Estimated completion is 2008-08.

What interventions are being tested in trial NCT00650858?

The interventions under investigation include: tissue plasminogen activator, rt-PA (thrombolytic) (Cathflo) (DRUG).

Who is sponsoring clinical trial NCT00650858?

This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00650858's enrollment target sits among peer trials

52 1181st of 2000 higher than 811 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00650858, the US trial registry maintained by the National Library of Medicine. NCT00650858 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.