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NCT00127218 · ClinicalTrials.gov registry record · Phase 3
High-Density Lipoprotein (HDL) Cholesterol Increased Plaque Stabilization in the Elderly
A Phase 3 study of Cardiovascular Disease and Atherosclerosis, sponsored by Johns Hopkins University.
- Completed
- Registry status
- Phase 3
- Development phase
- 145
- Enrollment target
- 1
- Study location
NCT00127218: Completed Phase 3 study of Cardiovascular Disease and Atherosclerosis, sponsored by Johns Hopkins University.
NCT00127218 is a Phase 3 study of Cardiovascular Disease and Atherosclerosis that has completed, run by Johns Hopkins University. The registered enrollment target is 145 participants, below the 2,696-participant average among 137 other Cardiovascular Disease trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00127218, a Phase 3 study of Cardiovascular Disease and Atherosclerosis, has completed, sponsored by Johns Hopkins University.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 145 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to investigate the added benefits of increased high-density lipoprotein (HDL) cholesterol serum levels over and above those achieved by lipid lowering therapy guided by current guidelines, in older individuals with cardiovascular disease.
Primary Outcome
The primary endpoint is Changes in plaque architecture and composition directly measured by magnetic resonance imaging (MRI) in the aorta and carotid arteries.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG niacin
- DRUG any statin
Study Locations (1)
Maryland
- Johns Hopkins Unversity School of Medicine - Baltimore
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 145 participants |
| Start Date | 2003-09 |
| Est. Completion | 2008-12 |
| Phase | Phase 3 |
What the finished NCT00127218 record still lists
NCT00127218 is an interventional study that assigns participants to a tested intervention. The registered 145 participants enrollment target is mid-sized for trials with a published cap, below the 2,696-participant average among 137 other Cardiovascular Disease trials with a reported enrollment target (95% lower).
The record links to 2 conditions, with Cardiovascular Disease appearing as the primary indexed condition, and to 3 interventions - of which Placebo is the first listed.
NCT00127218 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT00127218 about?
NCT00127218 is a clinical study titled "High-Density Lipoprotein (HDL) Cholesterol Increased Plaque Stabilization in the Elderly". The purpose of this study is to investigate the added benefits of increased high-density lipoprotein (HDL) cholesterol serum levels over and above those achieved by lipid lowering therapy guided by current guidelines, in older individuals with cardiovascular disease.
What is the current status of trial NCT00127218?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 145 participants. The study started on 2003-09. Estimated completion is 2008-12.
What conditions does trial NCT00127218 study?
This clinical trial studies the following conditions: Cardiovascular Disease, Atherosclerosis.
What interventions are being tested in trial NCT00127218?
The interventions under investigation include: Placebo (DRUG), niacin (DRUG), any statin (DRUG).
Who is sponsoring clinical trial NCT00127218?
This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00127218 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT00127218's enrollment target sits among peer trials
145 62nd of 137 higher than 76 of 137 other Cardiovascular Disease trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Cardiovascular Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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