H. Lee Moffitt Cancer Center and Research Institute
H. Lee Moffitt Cancer Center and Research Institute sponsors 502 registered US clinical trials on ClinicalTrials.gov, 82 of them currently recruiting, and 280 completed. 5 of these trials are in Phase 3-4 (later-stage) and 335 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Prostate Cancer, with 12 trials.
Trial Pipeline
502 total, page 5 of 11
Lymphodepletion Plus Adoptive Cell Therapy With High Dose IL-2 in Adolescent and Young Adult Patients With Soft Tissue Sarcoma
NCT04052334
Mobile APP Utilization for Enhanced Post-Operative Nutritional Recovery
NCT04091165
IRX-2 Regimen and Durvalumab, for Incurable H&N Squamous Cell Carcinoma
NCT03381183
Study of T-VEC in Locally Advanced Cutaneous Angiosarcoma
NCT03921073
Developing and Testing a Spanish-Language Intervention to Reduce Cancer-Related Sleep Disturbance
NCT04101526
Novel Exoscope System for 5-ALA Fluorescence-Guided Surgery for Gliomas
NCT04055688
Intratumorally-Administered Topotecan Using Convection-Enhanced Delivery in Patients With Grade III/ IV Glioma
NCT03927274
Avelumab With Radiotherapy in Patients With Leptomeningeal Disease
NCT03719768
Ibrutinib and PD-1 Blockade in High Risk Lymphocytic Leukemia
NCT03514017
Avadomide (CC-122) in Combination With Nivolumab in Advanced Melanoma
NCT03834623
Aromatase Inhibitor and Durvalumab in Postmenopausal Breast Cancer
NCT03874325
Dose Escalation Study of Minnelide in Relapsed or Refractory Acute Myeloid Leukemia
NCT03760523
Prospective Study of Personalized Approach to Inpatient Patients With Hyperglycemia
NCT03904199
CD40-L Blockade for Prevention of Acute Graft-Versus-Host Disease
NCT03605927
IRX-2 Regimen Combined With Nivolumab in Recurrent/Metastatic Solid Tumors
NCT03758781
Stereotactic Radiation and Nivolumab in the Management of Metastatic Breast Cancer Brain Metastases
NCT03807765
Emotional Support Messages Following a Cancer Diagnosis
NCT03840109
Development of a Mindfulness-Based Treatment for the Reduction of Alcohol Use and Smoking Cessation
NCT03734666
Immune Response and Potential Booster for Patients Who Have Received HER2-pulsed DC1
NCT03630809
TAS 102 in Combination With Ramucirumab in Advanced, Refractory Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma
NCT03686488
Radiation and Chemotherapy With Ipilimumab Followed by Nivolumab for Patients With Stage III Unresectable Non-Small Cell Lung Cancer (NSCLC)
NCT03663166
Regorafenib and Nivolumab in Mismatch Repair (MMR) Refractory Colorectal Cancer
NCT03712943
Vyxeos(CPX-351) in Adults w R/R Acute Lymphoblastic Leukemia
NCT03575325
Elotuzumab Plus Lenalidomide (Elo/Rev) for Serologic Relapse/Progression While on Lenalidomide
NCT03411031
Use of a Proliferation Saturation Index to Determine Personalized Radiotherapy for HPV + Oropharyngeal Cancers
NCT03656133
Pharmacogenomic-Guided Antidepressant Drug Prescribing in Cancer Patients
NCT03674138
Adaptive Tyrosine Kinase Inhibitor (TKI) Therapy In Patients With Thyroid Cancer
NCT03630120
Applying mHealth to Tobacco-related Health Disparities
NCT03404596
Study of Trametinib + Ceritinib in Patients With Unresectable Melanoma
NCT03501368
Improving Sleep in BMT Survivors
NCT03537963
Community Colorectal Cancer Awareness, Research, Education & Screening (C-CARES)
NCT03906110
Pembrolizumab and Vorinostat Combined With Temozolomide for Newly Diagnosed Glioblastoma
NCT03426891
Combination Immunotherapy-Ipilimumab-Nivolumab-Dendritic Cell p53 Vac - Patients With Small Cell Lung Cancer (SCLC)
NCT03406715
Pembrolizumab in Combination With Ibrutinib for Advanced, Refractory Colorectal Cancers
NCT03332498
Cetuximab & Nivolumab in Patients With Recurrent/Metastatic Head & Neck Squamous Cell Carcinoma
NCT03370276
Phase II Study of Pembrolizumab and Lenvatinib in Advanced Well-differentiated Neuroendocrine Tumors
NCT03290079
Preoperative Stereotactic Ablative Body Radiotherapy (SABR) for Early-Stage Breast Cancer
NCT03137693
Nivolumab and Tumor Infiltrating Lymphocytes (TIL) in Advanced Non-Small Cell Lung Cancer
NCT03215810
Pirfenidone Combined With Standard First-Line Chemotherapy in Advanced-Stage Lung NSCLC
NCT03177291
Facilitating Smoking Cessation With Reduced Nicotine Cigarettes
NCT02796391
Selinexor Plus High-Dose Melphalan (HDM) Before Autologous Hematopoietic Cell Transplantation for Multiple Myeloma
NCT02780609
Phase I-II Study of Interferon-gamma in Patients With HER-2 Positive Breast Cancer
NCT03112590
Patient Navigation in the Adolescent and Young Adult (AYA) Cancer Population
NCT03176576
A Phase I/II GVHD Prevention Trial Combining Pacritinib With Sirolimus-Based Immune Suppression
NCT02891603
Phase 1b/2 Safety and Efficacy of APR-246 w/Azacitidine for tx of TP53 Mutant Myeloid Neoplasms
NCT03072043
Screen to Save: NCI Colorectal Cancer Outreach & Screening Initiative
NCT05064410
Refining and Testing the Electronic Social Network Assessment Program (eSNAP)
NCT03026699
Talimogene Laherparepvec in Combination With Neoadjuvant Chemotherapy in Triple Negative Breast Cancer
NCT02779855
Interleukin-2 and Pembrolizumab for Metastatic Kidney Cancer
NCT02964078
Biobank for African American Prostate Cancer Research in Florida
NCT03232411
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 167 |
| Phase 2 | 168 |
| Phase 3 | 3 |
| Phase 4 | 2 |
Therapeutic Areas
What the Pipeline for H. Lee Moffitt Cancer Center and Research Institute Shows
According to the ClinicalTrials.gov registry, H. Lee Moffitt Cancer Center and Research Institute is linked to 502 US clinical trials across every stage of research activity. Of those, 82 studies are currently recruiting, about 16% of the sponsor's indexed portfolio, and 280 are already marked complete, representing roughly 56% of the total.
The phase mix for H. Lee Moffitt Cancer Center and Research Institute reports 5 late-stage studies (Phase 3 and Phase 4 combined) and 335 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for H. Lee Moffitt Cancer Center and Research Institute is Prostate Cancer with 12 linked trials, and 9 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.