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NCT03807765 · ClinicalTrials.gov registry record · Phase 1

Stereotactic Radiation and Nivolumab in the Management of Metastatic Breast Cancer Brain Metastases

A Phase 1 study of Metastatic Breast Cancer and Brain Metastases, sponsored by H. Lee Moffitt Cancer Center and Research Institute.

Completed
Registry status
Phase 1
Development phase
14
Enrollment target
1
Study location

NCT03807765 is a Phase 1 study of Metastatic Breast Cancer and Brain Metastases that has completed, run by H. Lee Moffitt Cancer Center and Research Institute. The registered enrollment target is 14 participants, below the 205-participant average among 139 other Metastatic Breast Cancer trials with a reported enrollment target (93% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT03807765, a Phase 1 study of Metastatic Breast Cancer and Brain Metastases, has completed, sponsored by H. Lee Moffitt Cancer Center and Research Institute.

COMPLETED
Registry status
Phase 1
Development phase
14 participants
Enrollment target
1
Study location

Study Summary

This study is to find out if administration of stereotactic radiosurgery (SRS) given after Nivolumab will improve overall response rate/anti-tumor activity in patients with metastatic breast cancer with brain metastases.

Interventions

  • DRUG Nivolumab
  • RADIATION Stereotactic Radiosurgery

Study Locations (1)

Florida

  • H. Lee Moffitt Cancer Center and Research Institute - Tampa

Trial Details

FieldValue
Enrollment Target 14 participants
Start Date 2019-01-30
Est. Completion 2025-03-18
Phase Phase 1

What the Registry Record Tells You About NCT03807765

The ClinicalTrials.gov registry entry for NCT03807765 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 14 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 205-participant average among 139 other Metastatic Breast Cancer trials with a reported enrollment target (93% lower). The listed sponsor is H. Lee Moffitt Cancer Center and Research Institute, which has 502 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Metastatic Breast Cancer appearing as the primary indexed condition, and to 2 interventions - of which Nivolumab is the first listed.

NCT03807765 reports 1 study location spanning 1 distinct geographic area - top geographies include Florida.

Frequently Asked Questions

What is clinical trial NCT03807765 about?

NCT03807765 is a clinical study titled "Stereotactic Radiation and Nivolumab in the Management of Metastatic Breast Cancer Brain Metastases". This study is to find out if administration of stereotactic radiosurgery (SRS) given after Nivolumab will improve overall response rate/anti-tumor activity in patients with metastatic breast cancer with brain metastases.

What is the current status of trial NCT03807765?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 14 participants. The study started on 2019-01-30. Estimated completion is 2025-03-18.

What conditions does trial NCT03807765 study?

This clinical trial studies the following conditions: Metastatic Breast Cancer, Brain Metastases.

What interventions are being tested in trial NCT03807765?

The interventions under investigation include: Nivolumab (DRUG), Stereotactic Radiosurgery (RADIATION).

Who is sponsoring clinical trial NCT03807765?

This trial is sponsored by H. Lee Moffitt Cancer Center and Research Institute, which has 502 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03807765 being conducted?

This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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