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NCT03072043 · ClinicalTrials.gov registry record · Phase 1

Phase 1b/2 Safety and Efficacy of APR-246 w/Azacitidine for tx of TP53 Mutant Myeloid Neoplasms

A Phase 1 study, sponsored by H. Lee Moffitt Cancer Center and Research Institute.

Completed
Registry status
Phase 1
Development phase
55
Enrollment target

NCT03072043 is a Phase 1 study that has completed, run by H. Lee Moffitt Cancer Center and Research Institute. The registered enrollment target is 55 participants.

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The verdict

NCT03072043, a Phase 1 study, has completed, sponsored by H. Lee Moffitt Cancer Center and Research Institute.

COMPLETED
Registry status
Phase 1
Development phase
55 participants
Enrollment target

Study Summary

The main purpose of this study is to determine the safe and recommended dose of APR-246 in combination with azacitidine as well as to see if this combination of therapy improves overall survival.

Interventions

  • DRUG Azacitidine
  • DRUG APR-246

Trial Details

FieldValue
Enrollment Target 55 participants
Start Date 2017-05-18
Est. Completion 2021-12-08
Phase Phase 1

What the Registry Record Tells You About NCT03072043

The ClinicalTrials.gov registry entry for NCT03072043 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 55 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is H. Lee Moffitt Cancer Center and Research Institute, which has 502 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Azacitidine is the first listed.

NCT03072043 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT03072043 about?

NCT03072043 is a clinical study titled "Phase 1b/2 Safety and Efficacy of APR-246 w/Azacitidine for tx of TP53 Mutant Myeloid Neoplasms". The main purpose of this study is to determine the safe and recommended dose of APR-246 in combination with azacitidine as well as to see if this combination of therapy improves overall survival.

What is the current status of trial NCT03072043?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 55 participants. The study started on 2017-05-18. Estimated completion is 2021-12-08.

What interventions are being tested in trial NCT03072043?

The interventions under investigation include: Azacitidine (DRUG), APR-246 (DRUG).

Who is sponsoring clinical trial NCT03072043?

This trial is sponsored by H. Lee Moffitt Cancer Center and Research Institute, which has 502 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.