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NCT03630120 · ClinicalTrials.gov registry record · Phase 2

Adaptive Tyrosine Kinase Inhibitor (TKI) Therapy In Patients With Thyroid Cancer

A Phase 2 study, sponsored by H. Lee Moffitt Cancer Center and Research Institute.

Terminated
Registry status
Phase 2
Development phase
6
Enrollment target

NCT03630120 is a Phase 2 study that was terminated before completion, run by H. Lee Moffitt Cancer Center and Research Institute. The registered enrollment target is 6 participants.

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The verdict

NCT03630120, a Phase 2 study, was terminated before completion, sponsored by H. Lee Moffitt Cancer Center and Research Institute.

TERMINATED
Registry status
Phase 2
Development phase
6 participants
Enrollment target

Study Summary

Participants will have been diagnosed with advanced progressive thyroid cancer and are about to start treatment with a tyrosine kinase inhibitor (TKI). The purpose of this study is to evaluate the efficacy and tolerability of tyrosine kinase inhibitor therapy (Lenvatinib or Sorafenib for differentiated thyroid cancer \[which includes papillary thyroid cancer, follicular thyroid cancer, and poorly differentiated thyroid cancer\]; and Cabozantinib or Vandetanib for medullary thyroid cancer) through adaptive (intermittent) versus conventional (continuous) regimen.

Interventions

  • DRUG Cabozantinib
  • DRUG Lenvatinib
  • DRUG Sorafenib
  • DRUG Vandetanib

Trial Details

FieldValue
Enrollment Target 6 participants
Start Date 2018-08-06
Est. Completion 2019-12-05
Phase Phase 2

What the Registry Record Tells You About NCT03630120

The ClinicalTrials.gov registry entry for NCT03630120 describes a study currently listed as terminated, categorized as Phase 2. The registered enrollment target is 6 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is H. Lee Moffitt Cancer Center and Research Institute, which has 502 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 4 interventions - of which Cabozantinib is the first listed.

NCT03630120 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT03630120 about?

NCT03630120 is a clinical study titled "Adaptive Tyrosine Kinase Inhibitor (TKI) Therapy In Patients With Thyroid Cancer". Participants will have been diagnosed with advanced progressive thyroid cancer and are about to start treatment with a tyrosine kinase inhibitor (TKI). The purpose of this study is to evaluate the efficacy and tolerability of tyrosine kinase inhibitor therapy (Lenvatinib or Sorafenib for differenti...

What is the current status of trial NCT03630120?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 6 participants. The study started on 2018-08-06. Estimated completion is 2019-12-05.

What interventions are being tested in trial NCT03630120?

The interventions under investigation include: Cabozantinib (DRUG), Lenvatinib (DRUG), Sorafenib (DRUG), Vandetanib (DRUG).

Who is sponsoring clinical trial NCT03630120?

This trial is sponsored by H. Lee Moffitt Cancer Center and Research Institute, which has 502 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.