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NCT03406715 · ClinicalTrials.gov registry record · Phase 2

Combination Immunotherapy-Ipilimumab-Nivolumab-Dendritic Cell p53 Vac - Patients With Small Cell Lung Cancer (SCLC)

A Phase 2 study, sponsored by H. Lee Moffitt Cancer Center and Research Institute.

Terminated
Registry status
Phase 2
Development phase
14
Enrollment target

NCT03406715 is a Phase 2 study that was terminated before completion, run by H. Lee Moffitt Cancer Center and Research Institute. The registered enrollment target is 14 participants.

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The verdict

NCT03406715, a Phase 2 study, was terminated before completion, sponsored by H. Lee Moffitt Cancer Center and Research Institute.

TERMINATED
Registry status
Phase 2
Development phase
14 participants
Enrollment target

Study Summary

The purpose of this study is to find out what effects (good and bad) immunotherapy treatment using the p53 vaccine (Ad.p53-DC) in combination with Nivolumab and Ipilimumab has on small cell lung cancer. Immunotherapy is a cancer therapy that uses the body's immune system to fight cancer cells. This study can be divided into three different phases: initial Induction Immunotherapy, Maintenance Immunotherapy and Retreatment.

Interventions

  • DRUG Nivolumab
  • DRUG Ipilimumab
  • BIOLOGICAL Dendritic Cell based p53 Vaccine

Trial Details

FieldValue
Enrollment Target 14 participants
Start Date 2018-03-15
Est. Completion 2022-05-16
Phase Phase 2

What the Registry Record Tells You About NCT03406715

The ClinicalTrials.gov registry entry for NCT03406715 describes a study currently listed as terminated, categorized as Phase 2. The registered enrollment target is 14 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is H. Lee Moffitt Cancer Center and Research Institute, which has 502 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which Nivolumab is the first listed.

NCT03406715 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT03406715 about?

NCT03406715 is a clinical study titled "Combination Immunotherapy-Ipilimumab-Nivolumab-Dendritic Cell p53 Vac - Patients With Small Cell Lung Cancer (SCLC)". The purpose of this study is to find out what effects (good and bad) immunotherapy treatment using the p53 vaccine (Ad.p53-DC) in combination with Nivolumab and Ipilimumab has on small cell lung cancer. Immunotherapy is a cancer therapy that uses the body's immune system to fight cancer cells. This...

What is the current status of trial NCT03406715?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 14 participants. The study started on 2018-03-15. Estimated completion is 2022-05-16.

What interventions are being tested in trial NCT03406715?

The interventions under investigation include: Nivolumab (DRUG), Ipilimumab (DRUG), Dendritic Cell based p53 Vaccine (BIOLOGICAL).

Who is sponsoring clinical trial NCT03406715?

This trial is sponsored by H. Lee Moffitt Cancer Center and Research Institute, which has 502 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.