H. Lee Moffitt Cancer Center and Research Institute

502 total trials 82 currently recruiting 280 completed

H. Lee Moffitt Cancer Center and Research Institute sponsors 502 registered US clinical trials on ClinicalTrials.gov, 82 of them currently recruiting, and 280 completed. 5 of these trials are in Phase 3-4 (later-stage) and 335 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Prostate Cancer, with 12 trials.

Trial Pipeline

502 total, page 6 of 11

COMPLETED

Oncology Research Information Exchange Network (ORIEN) Lung Cancer Study

NCT02803333

TERMINATED Phase 2

Phase 2 Durvalumab (Medi4736) for Bacillus Calmette-Guérin (BCG) Refactory Urothelial Carcinoma in Situ of the Bladder

NCT02901548

COMPLETED Phase 1

Ipilimumab + Nivolumab w/Thoracic Radiotherapy for Extensive-Stage Small Cell Lung Cancer

NCT03043599

TERMINATED Phase 2

FOLFIRINOX in Metastatic High Grade Gastroenteropancreatic Neuroendocrine Carcinomas

NCT03042780

COMPLETED Phase 1

Calcineurin Inhibitor-Free GVHD Prevention Regimen After Related Haplo PBSCT

NCT03018223

COMPLETED

Clinical Utility Assay as a Biomarker for Gastroenteropancreatic and Lung Neuroendocrine Tumors

NCT02948946

COMPLETED Phase 2

Nab-Paclitaxel and Gemcitabine for Recurrent/Refractory Sarcoma

NCT02945800

COMPLETED NA

Spanish-Language Smoking Cessation Trial

NCT02945787

COMPLETED

Determinants of Age-Related Treatment Effectiveness in Ovarian Cancer

NCT02973750

COMPLETED Phase 1

Capecitabine and Lenvatinib With External Radiation in Rectal Adenocarcinoma

NCT02935309

COMPLETED Phase 2

Study of Nivolumab in Patients With Advanced Refractory Biliary Tract Cancers

NCT02829918

COMPLETED Early Phase 1

Survivin Vaccine : Multiple Myeloma Autologous Hematopoietic Cell Transplant (HCT)

NCT02851056

COMPLETED Phase 1

Hypofractionated Stereotactic Irradiation With Nivolumab, Ipilimumab and Bevacizumab in Patients With Recurrent High Grade Gliomas

NCT02829931

COMPLETED Phase 2

Copanlisib (BAY 80-6946) in Combination With Gemcitabine and Cisplatin in Advanced Cholangiocarcinoma

NCT02631590

COMPLETED Phase 2

Panobinostat (LBH589): Multiple Myeloma - Autologous Hematopoietic Cell Transplantation (HCT)

NCT02722941

COMPLETED Early Phase 1

Combining PD-1 Blockade, CD137 Agonism and Adoptive Cell Therapy for Metastatic Melanoma

NCT02652455

COMPLETED Phase 2

Transarterial Chemoperfusion: Cisplatin, Methotrexate, Gemcitabine for Unresectable Pleural Mesothelioma

NCT02611037

COMPLETED Phase 2

Panobinostat (LBH589): Acute Graft Versus Host Disease (aGVHD) Prevention

NCT02588339

TERMINATED Early Phase 1

Fermented Wheat Germ Extract in Women With Ovarian Cancer

NCT02411565

COMPLETED Phase 1

TEEL Study- Phase 1 Tamoxifen and Ribociclib (LEE011) in Advanced ER+ (HER2 Negative) Breast Cancer

NCT02586675

COMPLETED Phase 4

Multicenter Study of Pharmacokinetic-Guided Docetaxel in Breast Cancer Patients Receiving Docetaxel and Cyclophosphamide

NCT02502864

COMPLETED Phase 1

Dose Escalation Study of Preoperative SBRT for High Risk Prostate Cancer

NCT02572284

COMPLETED Phase 2

Dose Dense Paclitaxel With Pembrolizumab (MK-3475) in Platinum Resistant Ovarian Cancer

NCT02440425

COMPLETED NA

Smoking-cessation: A Spanish-Language Clinical Trial

NCT02611076

COMPLETED Phase 2

AZD1775 Plus Carboplatin-Paclitaxel in Squamous Cell Lung Cancer

NCT02513563

COMPLETED Phase 2

Phase II Study of Ibrutinib in Advanced Carcinoid and Pancreatic Neuroendocrine Tumors

NCT02575300

COMPLETED NA

Cognitive Behavioral Intervention for Targeted Therapy Fatigue (CBT-TTF) Intervention

NCT02592447

COMPLETED NA

Using MC1R Genotype to Impact Melanoma Risk Behavior

NCT03509467

COMPLETED Phase 1

Hypofractionated Stereotactic Irradiation (HFSRT) With Pembrolizumab and Bevacizumab for Recurrent High Grade Gliomas

NCT02313272

COMPLETED

Assess Gamma H2AX Positivity in Circulating Prostate Cancer Cells Before and After Radium 223

NCT02981797

COMPLETED Phase 2

Phase 2 Trial of Selinexor (KPT-330) for Metastatic Triple Negative Breast Cancer (TNBC)

NCT02402764

COMPLETED Phase 1

A Study of Selinexor in Combination With Daunorubicin and Cytarabine for Untreated AML

NCT02403310

COMPLETED NA

Smoking Cessation Self-Help for Dual Users of Tobacco Cigarettes and E-Cigarettes

NCT02416011

COMPLETED

Pilot Testing of a Real-Time Oncogeriatric Teleconsultation System Using the Total Cancer Care™ Database

NCT02708381

COMPLETED Phase 1

Trametinib in Combination With Sorafenib in Patients With Advanced Hepatocellular Cancer

NCT02292173

COMPLETED Phase 1

Enzalutamide in Combination With Gemcitabine and Cisplatin in Bladder Cancer

NCT02300610

COMPLETED NA

Smoking Cessation for Cervical Cancer Survivors

NCT02157610

COMPLETED NA

Focal Prostate Radio-Frequency Ablation

NCT02328807

TERMINATED Phase 1

Selinexor in Combination With Irinotecan in Adenocarcinoma of Stomach and Distal Esophagus

NCT02283359

COMPLETED Phase 1

BYL719 in Combination With Gemcitabine and (Nab)-Paclitaxel in Locally Advanced and Metastatic Pancreatic Cancer

NCT02155088

COMPLETED Phase 1

Ex-vivo Expanded Donor Regulatory T Cells for Prevention of Acute Graft-Versus-Host Disease

NCT01795573

COMPLETED NA

Capitalizing on a Teachable Moment to Promote Smoking Cessation

NCT02276664

TERMINATED Phase 1

Fractionated Stereotactic Radiotherapy (FSRT) in Treatment of Brain Metastases

NCT02187822

COMPLETED Phase 1

HER-2 Pulsed DC Vaccine to Prevent Recurrence of Invasive Breast Cancer

NCT02063724

COMPLETED Phase 1

Selinexor (KPT-330) and Liposomal Doxorubicin For Relapsed and Refractory Multiple Myeloma

NCT02186834

COMPLETED Phase 1

Phase I/IIa Trial of Gemcitabine Plus Trastuzumab and Pertuzumab in Previously Treated Metastatic HER2+ Breast Cancer

NCT02139358

COMPLETED Phase 2

Capecitabine or 5-FU With Pegylated Interferon Alpha-2b in Unresectable/Metastatic Cutaneous Squamous Cell Carcinoma

NCT02218164

COMPLETED Early Phase 1

COGNUTRIN in Breast Cancer Survivors

NCT01823991

COMPLETED Early Phase 1

Translating Extinction Research to Improve Pharmacotherapy for Tobacco Dependence

NCT02202499

COMPLETED Phase 1

Stereotactic Body Radiotherapy and Concurrent Cisplatin for Re-Irradiation of Unresectable, Recurrent Squamous Cell Carcinomas of Head and Neck

NCT02158234

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Phase Distribution

PhaseTrial count
Phase 1 167
Phase 2 168
Phase 3 3
Phase 4 2

What the Pipeline for H. Lee Moffitt Cancer Center and Research Institute Shows

According to the ClinicalTrials.gov registry, H. Lee Moffitt Cancer Center and Research Institute is linked to 502 US clinical trials across every stage of research activity. Of those, 82 studies are currently recruiting, about 16% of the sponsor's indexed portfolio, and 280 are already marked complete, representing roughly 56% of the total.

The phase mix for H. Lee Moffitt Cancer Center and Research Institute reports 5 late-stage studies (Phase 3 and Phase 4 combined) and 335 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for H. Lee Moffitt Cancer Center and Research Institute is Prostate Cancer with 12 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.