H. Lee Moffitt Cancer Center and Research Institute
H. Lee Moffitt Cancer Center and Research Institute sponsors 502 registered US clinical trials on ClinicalTrials.gov, 82 of them currently recruiting, and 280 completed. 5 of these trials are in Phase 3-4 (later-stage) and 335 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Prostate Cancer, with 12 trials.
Trial Pipeline
502 total, page 6 of 11
Oncology Research Information Exchange Network (ORIEN) Lung Cancer Study
NCT02803333
Phase 2 Durvalumab (Medi4736) for Bacillus Calmette-Guérin (BCG) Refactory Urothelial Carcinoma in Situ of the Bladder
NCT02901548
Ipilimumab + Nivolumab w/Thoracic Radiotherapy for Extensive-Stage Small Cell Lung Cancer
NCT03043599
FOLFIRINOX in Metastatic High Grade Gastroenteropancreatic Neuroendocrine Carcinomas
NCT03042780
Calcineurin Inhibitor-Free GVHD Prevention Regimen After Related Haplo PBSCT
NCT03018223
Clinical Utility Assay as a Biomarker for Gastroenteropancreatic and Lung Neuroendocrine Tumors
NCT02948946
Nab-Paclitaxel and Gemcitabine for Recurrent/Refractory Sarcoma
NCT02945800
Spanish-Language Smoking Cessation Trial
NCT02945787
Determinants of Age-Related Treatment Effectiveness in Ovarian Cancer
NCT02973750
Capecitabine and Lenvatinib With External Radiation in Rectal Adenocarcinoma
NCT02935309
Study of Nivolumab in Patients With Advanced Refractory Biliary Tract Cancers
NCT02829918
Survivin Vaccine : Multiple Myeloma Autologous Hematopoietic Cell Transplant (HCT)
NCT02851056
Hypofractionated Stereotactic Irradiation With Nivolumab, Ipilimumab and Bevacizumab in Patients With Recurrent High Grade Gliomas
NCT02829931
Copanlisib (BAY 80-6946) in Combination With Gemcitabine and Cisplatin in Advanced Cholangiocarcinoma
NCT02631590
Panobinostat (LBH589): Multiple Myeloma - Autologous Hematopoietic Cell Transplantation (HCT)
NCT02722941
Combining PD-1 Blockade, CD137 Agonism and Adoptive Cell Therapy for Metastatic Melanoma
NCT02652455
Transarterial Chemoperfusion: Cisplatin, Methotrexate, Gemcitabine for Unresectable Pleural Mesothelioma
NCT02611037
Panobinostat (LBH589): Acute Graft Versus Host Disease (aGVHD) Prevention
NCT02588339
Fermented Wheat Germ Extract in Women With Ovarian Cancer
NCT02411565
TEEL Study- Phase 1 Tamoxifen and Ribociclib (LEE011) in Advanced ER+ (HER2 Negative) Breast Cancer
NCT02586675
Multicenter Study of Pharmacokinetic-Guided Docetaxel in Breast Cancer Patients Receiving Docetaxel and Cyclophosphamide
NCT02502864
Dose Escalation Study of Preoperative SBRT for High Risk Prostate Cancer
NCT02572284
Dose Dense Paclitaxel With Pembrolizumab (MK-3475) in Platinum Resistant Ovarian Cancer
NCT02440425
Smoking-cessation: A Spanish-Language Clinical Trial
NCT02611076
AZD1775 Plus Carboplatin-Paclitaxel in Squamous Cell Lung Cancer
NCT02513563
Phase II Study of Ibrutinib in Advanced Carcinoid and Pancreatic Neuroendocrine Tumors
NCT02575300
Cognitive Behavioral Intervention for Targeted Therapy Fatigue (CBT-TTF) Intervention
NCT02592447
Using MC1R Genotype to Impact Melanoma Risk Behavior
NCT03509467
Hypofractionated Stereotactic Irradiation (HFSRT) With Pembrolizumab and Bevacizumab for Recurrent High Grade Gliomas
NCT02313272
Assess Gamma H2AX Positivity in Circulating Prostate Cancer Cells Before and After Radium 223
NCT02981797
Phase 2 Trial of Selinexor (KPT-330) for Metastatic Triple Negative Breast Cancer (TNBC)
NCT02402764
A Study of Selinexor in Combination With Daunorubicin and Cytarabine for Untreated AML
NCT02403310
Smoking Cessation Self-Help for Dual Users of Tobacco Cigarettes and E-Cigarettes
NCT02416011
Pilot Testing of a Real-Time Oncogeriatric Teleconsultation System Using the Total Cancer Care™ Database
NCT02708381
Trametinib in Combination With Sorafenib in Patients With Advanced Hepatocellular Cancer
NCT02292173
Enzalutamide in Combination With Gemcitabine and Cisplatin in Bladder Cancer
NCT02300610
Smoking Cessation for Cervical Cancer Survivors
NCT02157610
Focal Prostate Radio-Frequency Ablation
NCT02328807
Selinexor in Combination With Irinotecan in Adenocarcinoma of Stomach and Distal Esophagus
NCT02283359
BYL719 in Combination With Gemcitabine and (Nab)-Paclitaxel in Locally Advanced and Metastatic Pancreatic Cancer
NCT02155088
Ex-vivo Expanded Donor Regulatory T Cells for Prevention of Acute Graft-Versus-Host Disease
NCT01795573
Capitalizing on a Teachable Moment to Promote Smoking Cessation
NCT02276664
Fractionated Stereotactic Radiotherapy (FSRT) in Treatment of Brain Metastases
NCT02187822
HER-2 Pulsed DC Vaccine to Prevent Recurrence of Invasive Breast Cancer
NCT02063724
Selinexor (KPT-330) and Liposomal Doxorubicin For Relapsed and Refractory Multiple Myeloma
NCT02186834
Phase I/IIa Trial of Gemcitabine Plus Trastuzumab and Pertuzumab in Previously Treated Metastatic HER2+ Breast Cancer
NCT02139358
Capecitabine or 5-FU With Pegylated Interferon Alpha-2b in Unresectable/Metastatic Cutaneous Squamous Cell Carcinoma
NCT02218164
COGNUTRIN in Breast Cancer Survivors
NCT01823991
Translating Extinction Research to Improve Pharmacotherapy for Tobacco Dependence
NCT02202499
Stereotactic Body Radiotherapy and Concurrent Cisplatin for Re-Irradiation of Unresectable, Recurrent Squamous Cell Carcinomas of Head and Neck
NCT02158234
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 167 |
| Phase 2 | 168 |
| Phase 3 | 3 |
| Phase 4 | 2 |
Therapeutic Areas
What the Pipeline for H. Lee Moffitt Cancer Center and Research Institute Shows
According to the ClinicalTrials.gov registry, H. Lee Moffitt Cancer Center and Research Institute is linked to 502 US clinical trials across every stage of research activity. Of those, 82 studies are currently recruiting, about 16% of the sponsor's indexed portfolio, and 280 are already marked complete, representing roughly 56% of the total.
The phase mix for H. Lee Moffitt Cancer Center and Research Institute reports 5 late-stage studies (Phase 3 and Phase 4 combined) and 335 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for H. Lee Moffitt Cancer Center and Research Institute is Prostate Cancer with 12 linked trials, and 9 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.