H. Lee Moffitt Cancer Center and Research Institute

502 total trials 82 currently recruiting 280 completed

H. Lee Moffitt Cancer Center and Research Institute sponsors 502 registered US clinical trials on ClinicalTrials.gov, 82 of them currently recruiting, and 280 completed. 5 of these trials are in Phase 3-4 (later-stage) and 335 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Prostate Cancer, with 12 trials.

Trial Pipeline

502 total, page 4 of 11

ACTIVE NOT RECRUITING Early Phase 1

Adaptive Abiraterone Therapy for Metastatic Castration Resistant Prostate Cancer

NCT02415621

NOT YET RECRUITING NA

Development of a Mindfulness-Based Smartphone Application for BMT Caregivers

NCT07352943

NOT YET RECRUITING NA

PRehabilitation Intervention to Modify Eating for Breast Cancer Patients (PRIME)

NCT07638150

NOT YET RECRUITING Phase 1

Safety and Efficacy of PIPAC Using Single Agent Mitomycin in Solid Tumors

NCT07487168

NOT YET RECRUITING NA

Modifying Diet to Improve Gut Microbiome

NCT03924778

NOT YET RECRUITING Phase 2

Evaluation and Outcomes of SAVI Scout MD for Localized Breast Surgery

NCT07686250

NOT YET RECRUITING NA

Wet Heparinized Suction for Abdominal Cancer

NCT05041335

NOT YET RECRUITING NA

Intermittent Fasting for Pancreatitis

NCT04760847

COMPLETED Phase 1

Mindfulness-Based Ecological Momentary Intervention For Smoking Cessation Among Cancer Survivors

NCT06476548

COMPLETED Phase 1

Irreversible Electroporation & Pembro Immunotherapy in Locally Advanced Pancreatic Cancer

NCT06378047

COMPLETED Early Phase 1

Cancer Coaching and Remote Education for Self-Empowerment (CARES) Study

NCT06323291

COMPLETED NA

Aim 1: App for Reducing Cravings to Smoke

NCT06923033

COMPLETED NA

Enhancing Cancer Survivorship With Pickleball

NCT06048822

COMPLETED Early Phase 1

Pilot Study of Nivolumab w/Ipilimumab or Relatlimab in Surgically Resectable Melanoma Brain Metastases

NCT05704933

COMPLETED Early Phase 1

Genomically Guided Radiation Dose Personalization in Locally Advanced NSCLC

NCT05873439

TERMINATED Early Phase 1

Siltuximab in Large Granular Lymphocytic Leukemia (LGLL)

NCT05316116

COMPLETED Phase 1

Dose Escalation/Dose Expansion Study of PRGN-3007 UltraCAR-T Cells in Patients With Advanced Hematologic and Solid Tumor Malignancies

NCT05694364

COMPLETED NA

STRONG Program for Cancer Patients

NCT05649969

COMPLETED

Feasibility of a Smart-Phone App for Patients With Advanced Renal Cell Carcinoma Undergoing Combination Immunotherapy

NCT05579847

COMPLETED

Exploring Men s Prostate Cancer Genetic Risk Perceptions

NCT06764992

COMPLETED NA

Caregiver Protocol for Remotely Improving, Monitoring, and Extending Quality of Life

NCT05379933

TERMINATED Phase 1

Maintenance Fedratinib to Prevent Post-Transplant Relapse in Myeloproliferative Neoplasms

NCT05127174

COMPLETED Phase 1

Duvelisib in Combination With BMS-986345 in Lymphoid Malignancy

NCT05065866

COMPLETED

Comparing Pre-Anesthesia Evaluation Via Telemedicine Versus in Person for Surgical Patients at Moffitt Cancer Center

NCT05065944

TERMINATED Phase 1

SELINEXOR in Combination w/Bevacizumab and Atezolizumab in Newly Diagnosed Advanced Hepatocellular Carcinoma

NCT05093608

COMPLETED

CARES-HCV: Promoting Screening Uptake Among Diverse Baby Boomers

NCT04980157

COMPLETED NA

Effect of Prolonged Nightly Fasting on Immunotherapy Outcomes in HNSCC - Role of Gut Microbiome

NCT05083416

COMPLETED

COVID-19 Immunogenicity of a Third Dose of mRNA-1273 Vaccine Among Cancer Patients

NCT05054218

COMPLETED

Adaptation Of An HPV Education Resource To Promote HPV Vaccination

NCT04974619

COMPLETED NA

Clinical Trials Outreach & Education

NCT05064423

COMPLETED NA

Motivating a Spectrum of Cancer Patients to Quit Smoking

NCT04914000

COMPLETED NA

Project HEALS (Helping and Empowering pAtients for Living a Life Smoke-free

NCT05362318

COMPLETED NA

Study to Develop a Group-Based E-Health Intervention for YA Cancer Survivors

NCT05048316

COMPLETED

Health Beliefs, Behaviors, and Healthcare Experiences Among United States Young and Mid-Age Adults

NCT04766164

COMPLETED Phase 1

CD8 Depleted, Non-engrafting, HLA Mismatched Unrelated Infusion With MDS and Secondary AML

NCT04620681

COMPLETED Phase 2

Neoadjuvant Immunotherapy With Tavo + Electroporation in Combination With Nivo. in Melanoma Patients

NCT04526730

COMPLETED

Addressing Barriers to Palliative Care Use in Bladder Cancer

NCT04598724

TERMINATED Phase 1

Immune Checkpoint Inhibition With Lurbinectedin Relapsed/Recurrent SCLC

NCT04610658

COMPLETED

Evaluation of EnVisio SmartClip for Intraoperative Localization of Breast Masses

NCT04604561

COMPLETED Phase 1

Study of CG0070 Combined With Nivolumab in Cisplatin Ineligible Patients With MIBC

NCT04610671

COMPLETED

SARS-CoV-2 (COVID-19) Immune Surveillance Among a Population Based Sample of Adults in Florida

NCT04596579

TERMINATED Phase 2

Cemiplimab-rwlc for Unresectable Locally Recurrent and/or Metastatic CSCC

NCT04242173

COMPLETED

Axicabtagene Ciloleucel:Neurocognitive and Patient-Reported Outcomes

NCT04319237

TERMINATED Early Phase 1

Contrast-Enhanced Ultrasound for the Evaluation of Changes in Tumor Blood Flow Surrounding HAE

NCT04150874

COMPLETED NA

Electronic Social Network Assessment Program (eSNAP) + Caregiver Navigator

NCT04268979

COMPLETED

Barriers to Screening Breast MRI Utilization Among Patients at Elevated Risk

NCT04257474

COMPLETED NA

Feasibility Study for Electroacupuncture for Chemotherapy- Induced Peripheral Neuropathy (CIPN)

NCT04092764

COMPLETED Phase 2

Reduced Intensity Flu/Mel/TBI Conditioning for HAPLO HCT Patients With Hematologic Malignancies

NCT04191187

TERMINATED Phase 2

TGR-1202 (Umbralisib) in Treatment Naïve Patients With Chronic Lymphocytic Leukemia (CLL)

NCT04163718

COMPLETED NA

Utilizing Augmented Reality as an Adjunct for Smoking Cessation

NCT04101422

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Phase Distribution

PhaseTrial count
Phase 1 167
Phase 2 168
Phase 3 3
Phase 4 2

What the Pipeline for H. Lee Moffitt Cancer Center and Research Institute Shows

According to the ClinicalTrials.gov registry, H. Lee Moffitt Cancer Center and Research Institute is linked to 502 US clinical trials across every stage of research activity. Of those, 82 studies are currently recruiting, about 16% of the sponsor's indexed portfolio, and 280 are already marked complete, representing roughly 56% of the total.

The phase mix for H. Lee Moffitt Cancer Center and Research Institute reports 5 late-stage studies (Phase 3 and Phase 4 combined) and 335 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for H. Lee Moffitt Cancer Center and Research Institute is Prostate Cancer with 12 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.