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NCT03921073 · ClinicalTrials.gov registry record · Phase 2

Study of T-VEC in Locally Advanced Cutaneous Angiosarcoma

A Phase 2 study, sponsored by H. Lee Moffitt Cancer Center and Research Institute.

Terminated
Registry status
Phase 2
Development phase
5
Enrollment target

NCT03921073: Clinical Trial Phase 2 study, sponsored by H. Lee Moffitt Cancer Center and Research Institute.

NCT03921073 is a Phase 2 study that was terminated before completion, run by H. Lee Moffitt Cancer Center and Research Institute. The registered enrollment target is 5 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03921073, a Phase 2 study, was terminated before completion, sponsored by H. Lee Moffitt Cancer Center and Research Institute.

TERMINATED
Registry status
Phase 2
Development phase
5 participants
Enrollment target

Study Summary

This is a single-arm study evaluating the efficacy of injecting Talimogene Laherparepvec T-VEC into Cutaneous Angiosarcoma tumors.

Primary Outcome

Overall response rate is defined as the proportion of patients who demonstrate complete or partial responses in injected lesions per modified Response Evaluation Criteria in Solid Tumors (RECIST) criteria appropriate for cutaneous neoplasms (ORR=complete response + partial response).

Interventions

  • DRUG T-VEC

Trial Details

FieldValue
Enrollment Target 5 participants
Start Date 2019-08-20
Est. Completion 2021-09-28
Phase Phase 2

Why NCT03921073 stopped before completion

NCT03921073 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 5 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (96% lower).

The record links to 0 conditions, and to 1 intervention - of which T-VEC is the first listed.

NCT03921073 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT03921073 about?

NCT03921073 is a clinical study titled "Study of T-VEC in Locally Advanced Cutaneous Angiosarcoma". This is a single-arm study evaluating the efficacy of injecting Talimogene Laherparepvec T-VEC into Cutaneous Angiosarcoma tumors.

What is the current status of trial NCT03921073?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 5 participants. The study started on 2019-08-20. Estimated completion is 2021-09-28.

What interventions are being tested in trial NCT03921073?

The interventions under investigation include: T-VEC (DRUG).

Who is sponsoring clinical trial NCT03921073?

This trial is sponsored by H. Lee Moffitt Cancer Center and Research Institute, which has 502 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT03921073's enrollment target sits among peer trials

5 2000th of 2000 the lowest of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT03921073, the US trial registry maintained by the National Library of Medicine. NCT03921073 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.