Duke University

1,725 total trials 187 currently recruiting 1244 completed

Duke University sponsors 1,725 registered US clinical trials on ClinicalTrials.gov, 187 of them currently recruiting, and 1,244 completed. 175 of these trials are in Phase 3-4 (later-stage) and 311 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Obesity, with 15 trials.

Trial Pipeline

1,725 total, page 29 of 35

COMPLETED Phase 2

Intravenous Palonosetron With Radiotherapy and Concomitant Temozolomide

NCT00900757

COMPLETED NA

Rheumatoid Arthritis Coping Enhancement

NCT04246827

COMPLETED

Cerebrospinal Fluid (CSF) Pharmacokinetics of Antimicrobials in Children

NCT00991185

COMPLETED NA

Exercise Dose-Response Effects in Prediabetes

NCT00962962

COMPLETED

Study of Intracranial Pressure (ICP) Monitoring in Critically Ill

NCT01330264

COMPLETED Phase 3

Effectiveness of Bridging Anticoagulation for Surgery (The BRIDGE Study)

NCT00786474

COMPLETED

Neuroimaging of Smokers With and Without Attention Deficit Hyperactivity Disorder (ADHD)

NCT01123668

COMPLETED NA

Mindfulness, Emotional Well-being, and Sleep Quality

NCT00887614

COMPLETED NA

Lidocaine For Neuroprotection During Cardiac Surgery

NCT00938964

TERMINATED Phase 2

Impact of Temsirolimus Therapy on Circulating Tumor Cell Biology In Men With Castration Resistant Metastatic Prostate Cancer

NCT00887640

COMPLETED

BraveNet Multi-Center Study on Integrative Medicine Treatment Approaches for Pain

NCT01186341

COMPLETED

The Genetics of Chiari Type I Malformation

NCT01060800

COMPLETED

Continuous Cardiac Arrhythmia Monitoring in Hemodialysis Patients

NCT00932659

TERMINATED Phase 4

Effect on Bleeding When Using FloSeal Matrix™ in Subjects Undergoing Endoscopic Vein Harvest (EVH)

NCT00742313

TERMINATED Phase 2

Atkins Diet and Prostate Cancer Clinical Trial

NCT00932672

COMPLETED Phase 3

Evaluation of a Tailored Smoking Cessation Treatment Algorithm Based on Initial Treatment Response and Genotype

NCT00894166

COMPLETED Phase 3

Treatment Effects of Escitalopram (Lexapro®) on Generalized Anxiety Disorder in Patients With HIV and AIDS

NCT00887679

COMPLETED Phase 2

Study of Plerixafor for Rescue of Poor Mobilizers in Autologous Stem Cell Transplant

NCT00901225

COMPLETED NA

Acceptance-Based Separated Family Treatment for Adolescent Anorexia Nervosa

NCT01274416

COMPLETED Phase 2

A Controlled Laboratory Study of the Effects on Cue-Induced Craving in Dependent Smokers

NCT00901459

TERMINATED Phase 2

Genomic Guided Therapy With Dasatinib or Nilutamide in Metastatic Castration-Resistant Prostate Cancer

NCT00918385

COMPLETED NA

Infection Rates of Myeloablative Allo SCT Recipients Receiving Neutropenic Diets Versus Non-Neutropenic Diets

NCT01687231

COMPLETED Phase 4

Comparing the Effectiveness of New Versus Older Treatments for Attention Deficit Hyperactivity Disorder (The NOTA Study)

NCT00889915

COMPLETED NA

Effect of Type 2 Diabetes Genetic Risk Information on Health Behaviors and Outcomes

NCT00849563

COMPLETED NA

p16 Methylation for Smoking Cessation

NCT01038492

TERMINATED Phase 4

Metformin for the Treatment of Nonalcoholic Fatty Liver Disease (NAFLD)

NCT00736385

COMPLETED

Alternate Dosing Schedules Study for HPV Vaccine (ADS)

NCT02280642

COMPLETED NA

Coping Skills and Heart Failure: Outcomes and Mechanisms

NCT00873418

COMPLETED Phase 1

Neurobiology of Nicotine and Non-nicotine Components of Tobacco Addiction

NCT01056926

COMPLETED

Validating PROMIS Instruments in Congestive Heart Failure Patients Receiving a Heart Transplant

NCT00783848

COMPLETED Phase 1

Lenalidomide and Decitabine in High Grade Myelodysplastic Syndromes

NCT00828802

COMPLETED Phase 4

Alternate Dosing Schedules Study for HPV Vaccine

NCT00862810

TERMINATED

Ventriculostomy in Subarachnoid Hemorrhage (SAH): Intracranial Pressure (ICP) Open or Not?

NCT01169454

COMPLETED NA

Targeted Feedback Reports to Improve Acute Coronary Syndromes (ACS) Care

NCT00952250

TERMINATED NA

Validation of Brain Oxygenation Monitor on Pediatric Patients

NCT00849940

COMPLETED Phase 1

Extinction Based Treatment for Nicotine Dependence

NCT00831155

COMPLETED NA

Post-traumatic Stress Disorder (PTSD), Addiction, and Virtual Reality

NCT01186315

COMPLETED NA

Erectile Dysfunction Study

NCT00873665

COMPLETED NA

Prevention of Intraoperative Nausea and Vomiting During Cesarean Section

NCT01216410

COMPLETED NA

Cholesterol, Hypertension and Glucose Education Study

NCT00815789

TERMINATED Phase 2

Multimodality Phase II Study in Prostate Cancer

NCT00734851

TERMINATED Phase 2

A Study of Gliadel Followed by Avastin + Irinotecan for Glioblastoma Multiforme (GBM)

NCT00735436

TERMINATED NA

Coping With High Grade Glioma

NCT00815152

COMPLETED NA

Spinal Cord Stimulator Implant Study

NCT00887419

COMPLETED NA

Impact of GBS on CVD in Type 2 Diabetes Mellitus

NCT00787670

COMPLETED

Ventriculostomies in SAH: ICP Open or Not?

NCT00787020

COMPLETED NA

Cognitive Effects of Inhalational Versus Intravenous General Anesthesia in the Elderly

NCT00788008

COMPLETED

Effectiveness of a Vaccination Program in the Community Ob/Gyn Setting

NCT00828555

COMPLETED Phase 1

Reduced Intensity Conditioning for Umbilical Cord Blood Transplant in Pediatric Patients With Non-Malignant Disorders

NCT00744692

COMPLETED NA

Escitalopram Treatment of Night Eating Syndrome

NCT00636649

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Phase Distribution

PhaseTrial count
Phase 1 136
Phase 2 175
Phase 3 41
Phase 4 134

What the Pipeline for Duke University Shows

According to the ClinicalTrials.gov registry, Duke University is linked to 1,725 US clinical trials across every stage of research activity. Of those, 187 studies are currently recruiting, about 11% of the sponsor's indexed portfolio, and 1,244 are already marked complete, representing roughly 72% of the total.

The phase mix for Duke University reports 175 late-stage studies (Phase 3 and Phase 4 combined) and 311 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for Duke University is Obesity with 15 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.