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NCT00831155 · ClinicalTrials.gov registry record · Phase 1

Extinction Based Treatment for Nicotine Dependence

A Phase 1 study, sponsored by Duke University.

Completed
Registry status
Phase 1
Development phase
257
Enrollment target

NCT00831155 is a Phase 1 study that has completed, run by Duke University. The registered enrollment target is 257 participants.

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The verdict

NCT00831155, a Phase 1 study, has completed, sponsored by Duke University.

COMPLETED
Registry status
Phase 1
Development phase
257 participants
Enrollment target

Study Summary

The purpose of this study is to test two quit smoking therapies and to study brain function while each therapy is being used. You will be randomly assigned (like flipping a coin) to one of the two groups. The first therapy is Extinction-Based therapy (EBT). If you are in this group, you will switch to smoking denicotinized cigarettes while wearing a 21 mg/d nicotine patch for one month prior to your quit date. The second therapy is a standard Nicotine Replacement therapy (NRT). If you are in this group, you will smoke your usual brand of cigarettes up to the quit date. Following the quit date, both groups will undergo standard nicotine replacement therapy (21 mg/d for 6 weeks; 14 mg/d for 2 weeks, 7 mg/d for 2 weeks). In addition to the above, we will recruit a sample of former smokers who are now regular users of e-cigarettes. This group \[ECIG\] will undergo the same screening and baseline assessments as the EBT and NRT groups up to the completion of fMRI1.

Interventions

  • DRUG Nicotine Patches, Denicotinized Cigarettes

Trial Details

FieldValue
Enrollment Target 257 participants
Start Date 2009-01
Est. Completion 2014-12
Phase Phase 1

Sponsor

Duke University

1,725 total trials

What the Registry Record Tells You About NCT00831155

The ClinicalTrials.gov registry entry for NCT00831155 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 257 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Duke University, which has 1,725 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Nicotine Patches, Denicotinized Cigarettes is the first listed.

NCT00831155 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00831155 about?

NCT00831155 is a clinical study titled "Extinction Based Treatment for Nicotine Dependence". The purpose of this study is to test two quit smoking therapies and to study brain function while each therapy is being used. You will be randomly assigned (like flipping a coin) to one of the two groups. The first therapy is Extinction-Based therapy (EBT). If you are in this group, you will switch ...

What is the current status of trial NCT00831155?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 257 participants. The study started on 2009-01. Estimated completion is 2014-12.

What interventions are being tested in trial NCT00831155?

The interventions under investigation include: Nicotine Patches, Denicotinized Cigarettes (DRUG).

Who is sponsoring clinical trial NCT00831155?

This trial is sponsored by Duke University, which has 1,725 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.