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NCT00788008 · ClinicalTrials.gov registry record · NA

Cognitive Effects of Inhalational Versus Intravenous General Anesthesia in the Elderly

A NA study, sponsored by Duke University.

Completed
Registry status
NA
Development phase
200
Enrollment target

NCT00788008: Completed NA study, sponsored by Duke University.

NCT00788008 is a NA study that has completed, run by Duke University. The registered enrollment target is 200 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (86% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00788008, a NA study, has completed, sponsored by Duke University.

COMPLETED
Registry status
NA
Development phase
200 participants
Enrollment target

Study Summary

The purpose of this research is to determine if post-operative cognition will be better if the general anesthesia for surgery is done with an inhaled (gas through a breathing tube) or intravenous (medicine injected in the IV) general anesthetic technique.

Primary Outcome

Mean change on composite scores (z-score) for memory and executive function measures. Memory measures: Hopkins Verbal Learning Test-Revised and the Brief Visuospatial Memory Test-Revised. Executive function measures: the Trail Making Test (Army, 1944), Digit-symbol substitution and Symbol Search subtests of the Processing Speed Index of the Wechsler Adult Intelligence Scale-III (WAIS-III; Wechsler, 1997) and the Controlled Oral Word Association subtest of the Multilingual Aphasia Examination.

Interventions

  • DRUG inhalation anesthesia with isoflurane vs. TIVA with propofol

Trial Details

FieldValue
Enrollment Target 200 participants
Start Date 2008-11
Est. Completion 2013-12
Phase NA
Duke University

1,725 total trials

What the finished NCT00788008 record still lists

NCT00788008 is an interventional study that assigns participants to a tested intervention. The registered 200 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (86% lower).

The record links to 0 conditions, and to 1 intervention - of which inhalation anesthesia with isoflurane vs. TIVA with propofol is the first listed.

NCT00788008 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00788008 about?

NCT00788008 is a clinical study titled "Cognitive Effects of Inhalational Versus Intravenous General Anesthesia in the Elderly". The purpose of this research is to determine if post-operative cognition will be better if the general anesthesia for surgery is done with an inhaled (gas through a breathing tube) or intravenous (medicine injected in the IV) general anesthetic technique.

What is the current status of trial NCT00788008?

This trial is currently completed. It is a NA study. The enrollment target is 200 participants. The study started on 2008-11. Estimated completion is 2013-12.

What interventions are being tested in trial NCT00788008?

The interventions under investigation include: inhalation anesthesia with isoflurane vs. TIVA with propofol (DRUG).

Who is sponsoring clinical trial NCT00788008?

This trial is sponsored by Duke University, which has 1,725 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00788008's enrollment target sits among peer trials

200 506th of 2000 higher than 1,434 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00788008, the US trial registry maintained by the National Library of Medicine. NCT00788008 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.