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NCT01123668 · ClinicalTrials.gov registry record

Neuroimaging of Smokers With and Without Attention Deficit Hyperactivity Disorder (ADHD)

A clinical trial, sponsored by Duke University.

Completed
Registry status
101
Enrollment target

NCT01123668 is a clinical trial that has completed, run by Duke University. The registered enrollment target is 101 participants.

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The verdict

NCT01123668 has completed, sponsored by Duke University.

COMPLETED
Registry status
101 participants
Enrollment target

Study Summary

The purpose of this study is to evaluate how nicotine, withdrawal from nicotine, and methylphenidate (a drug used for the treatment of ADHD) affect the brain of smokers with and without ADHD while doing tasks in an functional Magnetic Resonance Imaging scanner. Study Hypotheses: 1. compared to non-ADHD smokers, smokers with ADHD will exhibit greater abstinence-induced decrements in response inhibition performance and reward and greater concomitant disruptions of brain activity 2. administration of MPH to abstinent smokers will ameliorate response inhibition performance and reward deficits and task-related brain activation and this effect will be greater among ADHD smokers 3. genetic markers of dopamine neurotransmission will moderate abstinence- and MPH - induced changes in task-related brain activation across tasks.

Trial Details

FieldValue
Enrollment Target 101 participants
Start Date 2009-07
Est. Completion 2014-08

Sponsor

Duke University

1,725 total trials

What the Registry Record Tells You About NCT01123668

The ClinicalTrials.gov registry entry for NCT01123668 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 101 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Duke University, which has 1,725 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 0 interventions.

NCT01123668 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01123668 about?

NCT01123668 is a clinical study titled "Neuroimaging of Smokers With and Without Attention Deficit Hyperactivity Disorder (ADHD)". The purpose of this study is to evaluate how nicotine, withdrawal from nicotine, and methylphenidate (a drug used for the treatment of ADHD) affect the brain of smokers with and without ADHD while doing tasks in an functional Magnetic Resonance Imaging scanner. Study Hypotheses: 1. compared to non...

What is the current status of trial NCT01123668?

This trial is currently completed. The enrollment target is 101 participants. The study started on 2009-07. Estimated completion is 2014-08.

Who is sponsoring clinical trial NCT01123668?

This trial is sponsored by Duke University, which has 1,725 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.