Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00887679 · ClinicalTrials.gov registry record · Phase 3

Treatment Effects of Escitalopram (Lexapro®) on Generalized Anxiety Disorder in Patients With HIV and AIDS

A Phase 3 study of HIV Infections and Anxiety Disorders, sponsored by Duke University.

Completed
Registry status
Phase 3
Development phase
30
Enrollment target
1
Study location

NCT00887679: Completed Phase 3 study of HIV Infections and Anxiety Disorders, sponsored by Duke University.

NCT00887679 is a Phase 3 study of HIV Infections and Anxiety Disorders that has completed, run by Duke University. The registered enrollment target is 30 participants, below the 446-participant average among 542 other HIV Infections trials with a reported enrollment target (93% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00887679, a Phase 3 study of HIV Infections and Anxiety Disorders, has completed, sponsored by Duke University.

COMPLETED
Registry status
Phase 3
Development phase
30 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to evaluate whether escitalopram is safe, well tolerated, and effective in the treatment of HIV-infected patients with generalized anxiety disorder.

Primary Outcome

The HAM-A is administered by an interviewer who asks a series of questions related to symptoms of anxiety. The interviewer then rates the individual on a five-point scale for each of the 14 items. Seven of the items specifically address psychic anxiety and the remaining seven items address somatic anxiety. The total anxiety score ranges from 0 to 56, lower scores are better. Change from randomization to end of treatment in scores on the Hamilton Anxiety Rating Scale (HAM-A)is measured.

Interventions

  • DRUG Escitalopram

Study Locations (1)

North Carolina

  • Duke University Medical Center - Durham

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2009-05
Est. Completion 2010-09
Phase Phase 3
Duke University

1,725 total trials

What the finished NCT00887679 record still lists

NCT00887679 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 446-participant average among 542 other HIV Infections trials with a reported enrollment target (93% lower).

The record links to 2 conditions, with HIV Infections appearing as the primary indexed condition, and to 1 intervention - of which Escitalopram is the first listed.

NCT00887679 reports a single indexed study location in North Carolina.

Frequently Asked Questions

What is clinical trial NCT00887679 about?

NCT00887679 is a clinical study titled "Treatment Effects of Escitalopram (Lexapro®) on Generalized Anxiety Disorder in Patients With HIV and AIDS". The purpose of this study is to evaluate whether escitalopram is safe, well tolerated, and effective in the treatment of HIV-infected patients with generalized anxiety disorder.

What is the current status of trial NCT00887679?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 30 participants. The study started on 2009-05. Estimated completion is 2010-09.

What conditions does trial NCT00887679 study?

This clinical trial studies the following conditions: HIV Infections, Anxiety Disorders.

What interventions are being tested in trial NCT00887679?

The interventions under investigation include: Escitalopram (DRUG).

Who is sponsoring clinical trial NCT00887679?

This trial is sponsored by Duke University, which has 1,725 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00887679 being conducted?

This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for HIV Infections

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT00887679's enrollment target sits among peer trials

30 426th of 542 higher than 102 of 542 other HIV Infections trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other HIV Infections trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT00977977 · 30 participants · Phase 2

    Rituximab Plus Cyclosporine in Idiopathic Membranous Nephropathy

  • NCT01459107 · 30 participants · Phase 2

    Human Upper Extremity Allotransplantation

  • NCT01666080 · 30 participants · NA

    Second or Greater Allogeneic Hematopoietic Stem Cell Transplant Using Reduced Intensity Conditioning (RIC)

  • NCT01720836 · 30 participants · Phase 1

    Study of the Immune Response of MUC1 (Mucin1) Peptide Vaccine for Non-small Cell Lung Cancer

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT00887679, the US trial registry maintained by the National Library of Medicine. NCT00887679 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.