Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00742313 · ClinicalTrials.gov registry record · Phase 4

Effect on Bleeding When Using FloSeal Matrix™ in Subjects Undergoing Endoscopic Vein Harvest (EVH)

A Phase 4 study, sponsored by Duke University.

Terminated
Registry status
Phase 4
Development phase
50
Enrollment target

NCT00742313: Clinical Trial Phase 4 study, sponsored by Duke University.

NCT00742313 is a Phase 4 study that was terminated before completion, run by Duke University. The registered enrollment target is 50 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (90% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00742313, a Phase 4 study, was terminated before completion, sponsored by Duke University.

TERMINATED
Registry status
Phase 4
Development phase
50 participants
Enrollment target

Study Summary

This is a prospective, randomized trial to see in patients undergoing coronary artery bypass grafting and endoscopically-harvested greater saphenous vein, if using FloSeal Matrix in the endoscopically-harvested saphenous vein wound bed decreases bleeding and complications.

Primary Outcome

The number of participants with less than expected bleeding (bleeding typically expected for the vein grafting procedure) at the surgical site. Blood was collected in the Blake drain of the EVH wound bed treated with FloSeal MatrixFloSeal Matrix™in the tunnel of the endoscopically harvested Greater Saphenous vein.

Interventions

  • BIOLOGICAL FloSeal Matrix

Trial Details

FieldValue
Enrollment Target 50 participants
Start Date 2009-06
Est. Completion 2012-09
Phase Phase 4
Duke University

1,725 total trials

Why NCT00742313 stopped before completion

NCT00742313 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (90% lower).

The record links to 0 conditions, and to 1 intervention - of which FloSeal Matrix is the first listed.

NCT00742313 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00742313 about?

NCT00742313 is a clinical study titled "Effect on Bleeding When Using FloSeal Matrix™ in Subjects Undergoing Endoscopic Vein Harvest (EVH)". This is a prospective, randomized trial to see in patients undergoing coronary artery bypass grafting and endoscopically-harvested greater saphenous vein, if using FloSeal Matrix in the endoscopically-harvested saphenous vein wound bed decreases bleeding and complications.

What is the current status of trial NCT00742313?

This trial is currently terminated. It is a Phase 4 study. The enrollment target is 50 participants. The study started on 2009-06. Estimated completion is 2012-09.

What interventions are being tested in trial NCT00742313?

The interventions under investigation include: FloSeal Matrix (BIOLOGICAL).

Who is sponsoring clinical trial NCT00742313?

This trial is sponsored by Duke University, which has 1,725 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00742313's enrollment target sits among peer trials

50 1255th of 2000 higher than 678 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT00200889 · 50 participants · Early Phase 1

    Mapping Auricular Vagus Nerve Circuitry

  • NCT00409435 · 50 participants · Phase 2

    A Study of Pyridostigmine in Postural Tachycardia Syndrome

  • NCT01202305 · 50 participants

    The Use of Lymph Node Biopsies to Support HIV Pathogenesis Studies

  • NCT01225913 · 50 participants · Phase 4

    Mechanism(s) of Airflow Limitation During Exacerbation of Asthma

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT00742313, the US trial registry maintained by the National Library of Medicine. NCT00742313 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.