Duke University

1,725 total trials 187 currently recruiting 1244 completed

Duke University sponsors 1,725 registered US clinical trials on ClinicalTrials.gov, 187 of them currently recruiting, and 1,244 completed. 175 of these trials are in Phase 3-4 (later-stage) and 311 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Obesity, with 15 trials.

Trial Pipeline

1,725 total, page 28 of 35

COMPLETED Phase 2

Renal Optimization Strategies Evaluation in Acute Heart Failure and Reliable Evaluation of Dyspnea in the Heart Failure Network (ROSE) Study

NCT01132846

COMPLETED Phase 1

Single Dose Partial Breast Radiotherapy

NCT00944528

COMPLETED NA

Understanding of Genetic Risk Information for Type 2 Diabetes

NCT01186354

COMPLETED NA

PROspective Multicenter Imaging Study for Evaluation of Chest Pain

NCT01174550

COMPLETED

The MURDOCK Study Community Registry and Biorepository Multiple Sclerosis Cohort

NCT01723709

COMPLETED Phase 1

Treatment of Palmar Plantar Erythrodysesthesia (PPE) With Topical Sildenafil

NCT01219023

COMPLETED Phase 1

"Pharmacokinetic Study of Fondaparinux in Inpatients With Renal Dysfunction"

NCT01121770

COMPLETED NA

Community Based Obesity Prevention Among Blacks

NCT00939081

COMPLETED Phase 2

Using Allopurinol to Relieve Symptoms in Patients With Heart Failure and High Uric Acid Levels

NCT00987415

COMPLETED NA

Trial of Collaborative Depression Care Management for HIV Patients

NCT01372605

TERMINATED

Peripheral Blood Biomarkers in Idiopathic Interstitial Pneumonias

NCT01151527

TERMINATED Phase 2

Epigenetic Modulation in Relapsed/Refractory Follicular Lymphoma and Marginal Zone Lymphoma

NCT01121757

COMPLETED NA

Centers for Education on Research and Therapeutics - Heart Failure: Targeted Intervention Study

NCT00979264

COMPLETED NA

Outlook: An Intervention to Improve Quality of Life in Serious Illness

NCT00939146

COMPLETED NA

Uncertainty Management Intervention

NCT00938795

COMPLETED

Mother Sibling Interactions Following Very Low Birth Weight (VLBW) Infant Homecoming

NCT01385254

COMPLETED NA

Stroke Education Intervention Trial - Pilot

NCT01115660

COMPLETED Phase 1

An Open Label Study to Describe the Pharmacokinetics of Daptomycin in Infants

NCT00942149

COMPLETED NA

Parent Treatment for Child Social Adjustment

NCT01765166

TERMINATED Phase 4

Moderate to Persistent Asthma in the Obese Subject

NCT01016847

TERMINATED Phase 1

Local Modulation of Immune Receptors to Enhance the Response to Dendritic Cell Vaccination in Metastatic Melanoma

NCT01216436

COMPLETED Phase 2

Avastin/Radiation (XRT)/Temozolomide (Temodar) Followed by Avastin/Temodar/Topotecan for Glioblastoma

NCT01004874

COMPLETED NA

Care Transitions for Complex Patient - Cycle 1 and Cycle 2

NCT01039324

COMPLETED NA

Optimal Planning Target Volume With Stereotactic Radiosurgery

NCT01017497

COMPLETED NA

Radiosurgery and Avastin for Recurrent Malignant Gliomas

NCT01017250

TERMINATED Phase 4

Vyvanse and Glucose Intolerance in Children With Attention Deficit Hyperactivity Disorder (ADHD) and Obesity

NCT01017263

TERMINATED Phase 4

Memantine and Postoperative Pain

NCT01032759

COMPLETED NA

Stereotactic Body Radiotherapy (SBRT) for Prostate Cancer

NCT00941915

COMPLETED NA

Supplemental Nicotine Administration for Smoking Cessation in Posttraumatic Stress Disorder (PTSD)

NCT01055886

COMPLETED

Obesity in HIV After Antiretroviral Therapy

NCT01461876

COMPLETED NA

Community Based Obesity Prevention Among Black Women

NCT00938535

COMPLETED Phase 1

Rivastigmine Study in Adolescents With Down Syndrome

NCT01084135

COMPLETED Phase 3

Evaluating the Effectiveness of Prednisone, Azathioprine, and N-acetylcysteine in Patients With IPF

NCT00650091

COMPLETED Phase 3

Cerebral Perfusion Pressure Using Precedex and Other Sedatives

NCT01169467

TERMINATED

Functional Imaging of Tumor and Normal Tissue

NCT00933114

TERMINATED Phase 3

AntiCoagulant Effectiveness in Idiopathic Pulmonary Fibrosis

NCT00957242

COMPLETED Phase 1

Esophageal Sparing Intensity-modulated Radiation Therapy (IMRT) for Locally-Advanced Thoracic Malignancies

NCT00921739

COMPLETED NA

Clinical Decision Support for Medication Management and Adherence

NCT00979225

COMPLETED

Intraoperative OCT Guidance of Intraocular Surgery

NCT01588041

COMPLETED NA

The Effect of Depth of Anesthesia as Measured by Bispectral Index (BIS) on Emergence Agitation in Children

NCT00990769

COMPLETED NA

CONNECT for Quality: A Study to Reduce Falls in Nursing Homes

NCT00636675

COMPLETED NA

Teen CHAT: Improving Physician Communication With Adolescents About Healthy Weight

NCT01040975

COMPLETED NA

Mechanisms and Functional Outcomes of Exercise Progression Models in the Elderly

NCT01899586

COMPLETED

Fast Spectral Imaging Device for Tumor Margin Mapping

NCT01107080

COMPLETED NA

Nonin 4 Wavelength Cerebral Oximeter Study

NCT01762722

COMPLETED NA

Stress Management and Biomarkers of Risk in Cardiac Rehabilitation

NCT00981253

COMPLETED NA

Enhanced Self-Efficacy Training

NCT00938769

COMPLETED Phase 4

Impact of Aggressive Versus Standard Drainage Regimen Using a Long Term Indwelling Pleural Catheter

NCT00978939

COMPLETED NA

Tailored Intervention Protocol for Oral Chemotherapy Adherence

NCT00932490

COMPLETED

The CARRA Registry

NCT01697254

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Phase Distribution

PhaseTrial count
Phase 1 136
Phase 2 175
Phase 3 41
Phase 4 134

What the Pipeline for Duke University Shows

According to the ClinicalTrials.gov registry, Duke University is linked to 1,725 US clinical trials across every stage of research activity. Of those, 187 studies are currently recruiting, about 11% of the sponsor's indexed portfolio, and 1,244 are already marked complete, representing roughly 72% of the total.

The phase mix for Duke University reports 175 late-stage studies (Phase 3 and Phase 4 combined) and 311 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for Duke University is Obesity with 15 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.