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NCT00744692 · ClinicalTrials.gov registry record · Phase 1
Reduced Intensity Conditioning for Umbilical Cord Blood Transplant in Pediatric Patients With Non-Malignant Disorders
A Phase 1 study of Thalassemia and Hemoglobinopathies, sponsored by Duke University.
- Completed
- Registry status
- Phase 1
- Development phase
- 22
- Enrollment target
- 1
- Study location
NCT00744692: Completed Phase 1 study of Thalassemia and Hemoglobinopathies, sponsored by Duke University.
NCT00744692 is a Phase 1 study of Thalassemia and Hemoglobinopathies that has completed, run by Duke University. The registered enrollment target is 22 participants, below the 89-participant average among 19 other Thalassemia trials with a reported enrollment target (75% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00744692, a Phase 1 study of Thalassemia and Hemoglobinopathies, has completed, sponsored by Duke University.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 22 participants
- Enrollment target
- 1
- Study location
Study Summary
The primary objective is to determine the feasibility of attaining acceptable rates of donor cell engraftment (\>25% donor chimerism at 180 days) following reduced intensity conditioning (RIC) regimens in pediatric patients \< 21 years receiving cord blood transplantation for non-malignant disorders.
Primary Outcome
Determine the feasibility of attaining acceptable rates of donor cell engraftment (\>25% donor cells at 180 days) following reduced intensity conditioning regimens in children \< 21 years receiving cord blood transplant for non-malignant disorders.
Conditions Studied
Interventions
- DRUG Reduced Intensity Conditioning
- BIOLOGICAL Unrelated Umbilical Cord Blood Transplant
Study Locations (1)
North Carolina
- Duke University Medical Center Pediatric Blood and Marrow Transplant Program - Durham
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 22 participants |
| Start Date | 2008-10 |
| Est. Completion | 2014-04 |
| Phase | Phase 1 |
What the finished NCT00744692 record still lists
NCT00744692 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 22 participants, a relatively small participant target, below the 89-participant average among 19 other Thalassemia trials with a reported enrollment target (75% lower).
The record links to 8 conditions, with Thalassemia appearing as the primary indexed condition, and to 2 interventions - of which Reduced Intensity Conditioning is the first listed.
NCT00744692 reports a single indexed study location in North Carolina.
Frequently Asked Questions
What is clinical trial NCT00744692 about?
NCT00744692 is a clinical study titled "Reduced Intensity Conditioning for Umbilical Cord Blood Transplant in Pediatric Patients With Non-Malignant Disorders". The primary objective is to determine the feasibility of attaining acceptable rates of donor cell engraftment (\>25% donor chimerism at 180 days) following reduced intensity conditioning (RIC) regimens in pediatric patients \< 21 years receiving cord blood transplantation for non-malignant disorders...
What is the current status of trial NCT00744692?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 22 participants. The study started on 2008-10. Estimated completion is 2014-04.
What conditions does trial NCT00744692 study?
This clinical trial studies the following conditions: Thalassemia, Hemoglobinopathies, Immunodeficiencies, Inborn Errors of Metabolism, Non-malignant Disorders.
What interventions are being tested in trial NCT00744692?
The interventions under investigation include: Reduced Intensity Conditioning (DRUG), Unrelated Umbilical Cord Blood Transplant (BIOLOGICAL).
Who is sponsoring clinical trial NCT00744692?
This trial is sponsored by Duke University, which has 1,725 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00744692 being conducted?
This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT00744692's enrollment target sits among peer trials
22 13th of 19 higher than 6 of 19 other Thalassemia trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Thalassemia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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