Colgate Palmolive
Colgate Palmolive sponsors 51 registered US clinical trials on ClinicalTrials.gov, 3 of them currently recruiting, and 45 completed. 38 of these trials are in Phase 3-4 (later-stage) and 6 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Gingivitis, with 3 trials.
Trial Pipeline
51 total, page 1 of 2
Clinical Study to Collect and Analyze Dental Plaque and Oral Health Measures in a Population With High Plaque/Low Gingivitis and High Plaque/High Gingivitis
NCT07614490
Clinical Study to Assess the Efficacy of New Toothpaste Containing SnF as Compared to Colgate Cavity Protection Toothpaste on the Reduction of Enamel Erosion
NCT07442136
Efficacy of a Stannous Fluoride Toothpaste, Cetylpyridinium Chloride Mouthwash, and Battery Toothbrush Regimen in Reducing Established Dental Plaque and Gingivitis.
NCT07398846
To Assess the Efficacy of Two Brushing Regimens: in the Reduction of Established Dental Plaque and Gingivitis.
NCT07605338
To Validate Changes in Knowledge, Attitudes and Practices (KAPs) Related to the Know Your OQ Initiative and to Understand the Readability, Comprehension and Ease of Use of the Know Your OQ Quiz
NCT06880458
Investigation of the Interplay Between Local Oral Inflammation, Microbiota and Systemic Immune Responses.
NCT06966492
Clinical Study to Evaluate the Tooth Whitening Efficacy of a New NextGen In-office Whitening System
NCT07225478
To Assess the Efficacy of a Toothpaste Containing 8% Arginine as Compared to Colgate Cavity Protection Toothpaste in the Reduction of Dentinal Hypersensitivity.
NCT07149376
Oothpaste Containing 8% Arginine Compared to Colgate Cavity Protection Toothpaste in Reducing Dentinal Hypersensitivity
NCT07257042
Comparative Efficacy of Floss and Essential Oil/CPC+Zn Mouthwashes in Reducing Dental Plaque and Gingivitis
NCT07029438
Clinical Study to Evaluate the Tooth Whitening Efficacy
NCT06957249
Clinical Study to Assess the Efficacy of Professional Tooth Whitening Maintenance System
NCT06613347
Assessing the Colgate Assist Handle Toothbrush in Individuals With Impairment of Hand Movement.
NCT06632704
Clinical Investigation to Assess the Efficacy of Manual Toothbrushes in the Reduction of Plaque and Gingivitis.
NCT06565897
Arginine Plaque Metabolism Pilot Clinical Study
NCT06954779
Clinical Research Study to Assess the Efficacy of Two Brushing Regimens in the Reduction of Established Dental Plaque and Gingivitis.
NCT06244303
Maximal Use Study to Determine the Pharmacokinetics of L-arginine After Exaggerated Oral Use of COL101
NCT06182267
Children in the Operating Room: Kids That go Thru Operating Room Will be Given a Connected Health Toothbrush, Kids Anticavity Toothpaste and Behavioral Health Intervention to Reduce Claim Costs
NCT07539064
Documenting Toothbrushing Experiences of Caregivers Who Care for Children With Autism Spectrum Disorders
NCT05552144
A Clinical Trial to Assess the Safety and the Anti-caries Efficacy of COL 101 (Arginine) Non-fluoride Dentifrices in Comparison With 0.24% Sodium Fluoride (1100 Ppm F) Dentifrice Control in 10 to 14-year-old Children
NCT04750902
Measurement of Viral Load Reduction in the Oral Cavity After a Regimental Use of OC Toothpaste Products
NCT04864925
Clinical Efficacy of Single-Use of Peroxyl Mouthwash for Reducing Bacteria Saliva and Bioaerosol Contamination Phase 2
NCT04717063
Clinical Efficacy of Single-Use of Peroxyl Mouthwash for Reducing Bacteria in Saliva and Bioaerosol Contamination
NCT04626778
Dentinal Hypersensitivity Reduction
NCT06244290
Gingivitis Reduction After Use of 0.45% Stannous Fluoride Toothpaste
NCT06300866
Clinical Investigation Examining Plaque and Gingivitis Connected Toothbrush Compared to Non-Connected Toothbrush
NCT04221334
Clinical Investigation of a Toothpaste Containing Stannous Fluoride as Compared to Colgate Fluoride Toothpaste
NCT04033575
Clinical Study Comparing Dental Plaque and Gingivitis Reduction After Using One of Three Oral Hygiene Multi-component Regimens (Using of a Manual Toothbrush, a Toothpaste and a Mouthwash)
NCT02366689
The Clinical Investigation of Toothpaste as Compared to Toothpaste and Mouthwash in Reducing Plaque and Gingivitis: A Six-week Clinical Study in the US
NCT02360995
Clinical Investigation to Examine Toothpaste Effect on Oral Bacteria
NCT02194621
Compare Anti-inflammatory Dentifrices
NCT00762528
The Efficacy of a Toothpaste to Reduce Sensitivity
NCT00763269
Clinical Efficacy of 10% Arginine Bicarbonate Prophylaxis Paste
NCT01072188
Clinical Study to Evaluate Dental Plaque
NCT00758290
Clinical Efficacy of a Toothpaste on Hypersensitivity Reduction
NCT01040169
Investigate Oral Bacteria in Adult Population
NCT00762177
Study to Determine the Anti-plaque Efficacy of Commerical Toothpastes and an Oral Rinse
NCT01024738
Compare the Clinical Efficacy of Prototype Toothpastes.
NCT00761930
Collection of Gingival Crevicular Fluid From Periodontitis Patients
NCT00763048
Train New Examiners Via Modified Gingival Margin Plaque
NCT00758563
Clinical Study to Evaluate the Treatment of Gingivitis of Two Toothpastes
NCT00762515
Investigation of Dental Plaque and Gingival Index
NCT00759031
Evaluate Clinical Research From Commerical Oral Care Products
NCT00759187
Compare the Clinical Efficacy of Prototype Toothpastes
NCT00926029
Training and Calibration of Dental Examiners
NCT00765167
Development of Clinical Method to Determination Triclosan Retention in Plaque Following Brushing.
NCT00966953
Clinical Research Study Efficacy of a Prototype Oral Rinse
NCT01021007
Clinical Study to Compare Dental Plaque Control
NCT00758394
Evaluating Commercial Anti-Plaque Products and Oral Rinse
NCT01014143
Clinical Study to Examine Brushing on Dental Implants
NCT00762619
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 5 |
| Phase 3 | 29 |
| Phase 4 | 9 |
Therapeutic Areas
What the Pipeline for Colgate Palmolive Shows
According to the ClinicalTrials.gov registry, Colgate Palmolive is linked to 51 US clinical trials across every stage of research activity. Of those, 3 studies are currently recruiting, about 6% of the sponsor's indexed portfolio, and 45 are already marked complete, representing roughly 88% of the total.
The phase mix for Colgate Palmolive reports 38 late-stage studies (Phase 3 and Phase 4 combined) and 6 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for Colgate Palmolive is Gingivitis with 3 linked trials, and 7 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.