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NCT06954779 · ClinicalTrials.gov registry record · Phase 3

Arginine Plaque Metabolism Pilot Clinical Study

A Phase 3 study, sponsored by Colgate Palmolive.

Completed
Registry status
Phase 3
Development phase
20
Enrollment target

NCT06954779: Completed Phase 3 study, sponsored by Colgate Palmolive.

NCT06954779 is a Phase 3 study that has completed, run by Colgate Palmolive. The registered enrollment target is 20 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06954779, a Phase 3 study, has completed, sponsored by Colgate Palmolive.

COMPLETED
Registry status
Phase 3
Development phase
20 participants
Enrollment target

Study Summary

Proof of concept clinical study to measure plaque metabolism and the prebiotic efficacy of arginine-containing toothpaste.

Primary Outcome

Fasting plaque will be collected before and after a sucrose rinse for lactic acid analysis and ammonia production.The plaque pH of collected samples will also be measured to provide trend data.

Interventions

  • DRUG Colgate Cavity Protection
  • DRUG TOM's Superior Sensitivity Relief Toothpaste

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2024-07-24
Est. Completion 2024-09-20
Phase Phase 3
Colgate Palmolive

51 total trials

What the finished NCT06954779 record still lists

NCT06954779 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (97% lower).

The record links to 0 conditions, and to 2 interventions - of which Colgate Cavity Protection is the first listed.

NCT06954779 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT06954779 about?

NCT06954779 is a clinical study titled "Arginine Plaque Metabolism Pilot Clinical Study". Proof of concept clinical study to measure plaque metabolism and the prebiotic efficacy of arginine-containing toothpaste.

What is the current status of trial NCT06954779?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 20 participants. The study started on 2024-07-24. Estimated completion is 2024-09-20.

What interventions are being tested in trial NCT06954779?

The interventions under investigation include: Colgate Cavity Protection (DRUG), TOM's Superior Sensitivity Relief Toothpaste (DRUG).

Who is sponsoring clinical trial NCT06954779?

This trial is sponsored by Colgate Palmolive, which has 51 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT06954779's enrollment target sits among peer trials

20 1956th of 2000 higher than 32 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06954779, the US trial registry maintained by the National Library of Medicine. NCT06954779 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.