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NCT07225478 · ClinicalTrials.gov registry record · Phase 3
Clinical Study to Evaluate the Tooth Whitening Efficacy of a New NextGen In-office Whitening System
A Phase 3 study, sponsored by Colgate Palmolive.
- Completed
- Registry status
- Phase 3
- Development phase
- 180
- Enrollment target
NCT07225478: Completed Phase 3 study, sponsored by Colgate Palmolive.
NCT07225478 is a Phase 3 study that has completed, run by Colgate Palmolive. The registered enrollment target is 180 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (77% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07225478, a Phase 3 study, has completed, sponsored by Colgate Palmolive.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 180 participants
- Enrollment target
Study Summary
The goal of this clinical study is to evaluate how well a new in-office whitening system works to whiten teeth compared to some other commercially available in-office whitening systems.
Primary Outcome
The primary outcome variable of this study will be tooth shade whitening improvements via the Vita Extended BleachedGuide 3D-Master (29 tabs).
Interventions
- DRUG Fluoride Toothpaste
- DEVICE Soft Manual Toothbrush
- DRUG Beaming White
- COMBINATION_PRODUCT Philips Zoom Professional Whitening Treatment
- COMBINATION_PRODUCT Opalescence Boost PF
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 180 participants |
| Start Date | 2025-10-31 |
| Est. Completion | 2025-12-21 |
| Phase | Phase 3 |
What the finished NCT07225478 record still lists
NCT07225478 is an interventional study that assigns participants to a tested intervention. The registered 180 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (77% lower).
The record links to 0 conditions, and to 5 interventions - of which Fluoride Toothpaste is the first listed.
NCT07225478 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07225478 about?
NCT07225478 is a clinical study titled "Clinical Study to Evaluate the Tooth Whitening Efficacy of a New NextGen In-office Whitening System". The goal of this clinical study is to evaluate how well a new in-office whitening system works to whiten teeth compared to some other commercially available in-office whitening systems.
What is the current status of trial NCT07225478?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 180 participants. The study started on 2025-10-31. Estimated completion is 2025-12-21.
What interventions are being tested in trial NCT07225478?
The interventions under investigation include: Fluoride Toothpaste (DRUG), Soft Manual Toothbrush (DEVICE), Beaming White (DRUG), Philips Zoom Professional Whitening Treatment (COMBINATION_PRODUCT), Opalescence Boost PF (COMBINATION_PRODUCT).
Who is sponsoring clinical trial NCT07225478?
This trial is sponsored by Colgate Palmolive, which has 51 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07225478's enrollment target sits among peer trials
180 1422nd of 2000 higher than 564 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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