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NCT07257042 · ClinicalTrials.gov registry record · Phase 3
Oothpaste Containing 8% Arginine Compared to Colgate Cavity Protection Toothpaste in Reducing Dentinal Hypersensitivity
A Phase 3 study, sponsored by Colgate Palmolive.
- Completed
- Registry status
- Phase 3
- Development phase
- 80
- Enrollment target
NCT07257042: Completed Phase 3 study, sponsored by Colgate Palmolive.
NCT07257042 is a Phase 3 study that has completed, run by Colgate Palmolive. The registered enrollment target is 80 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (90% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07257042, a Phase 3 study, has completed, sponsored by Colgate Palmolive.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 80 participants
- Enrollment target
Study Summary
The objective of this study is to assess clinical efficacy of a toothpaste containing 8% arginine (Colgate-Palmolive Company, New York, NY, USA) to provide dental hypersensitivity relief (tactile and air blast) in comparison to Colgate Cavity Protection Toothpaste (Colgate-Palmolive Company, New York, NY, USA) over an eight-week period.
Primary Outcome
Sensitivity will be defined by a score in the range of 10-50 gms. of force
Interventions
- DRUG Colgate Cavity Protection Toothpaste
- DRUG Toothpaste containing 8% Arginine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 80 participants |
| Start Date | 2025-07-14 |
| Est. Completion | 2025-11-04 |
| Phase | Phase 3 |
What the finished NCT07257042 record still lists
NCT07257042 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 80 participants, a relatively small participant target, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (90% lower).
The record links to 0 conditions, and to 2 interventions - of which Colgate Cavity Protection Toothpaste is the first listed.
NCT07257042 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07257042 about?
NCT07257042 is a clinical study titled "Oothpaste Containing 8% Arginine Compared to Colgate Cavity Protection Toothpaste in Reducing Dentinal Hypersensitivity". The objective of this study is to assess clinical efficacy of a toothpaste containing 8% arginine (Colgate-Palmolive Company, New York, NY, USA) to provide dental hypersensitivity relief (tactile and air blast) in comparison to Colgate Cavity Protection Toothpaste (Colgate-Palmolive Company, New Yor...
What is the current status of trial NCT07257042?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 80 participants. The study started on 2025-07-14. Estimated completion is 2025-11-04.
What interventions are being tested in trial NCT07257042?
The interventions under investigation include: Colgate Cavity Protection Toothpaste (DRUG), Toothpaste containing 8% Arginine (DRUG).
Who is sponsoring clinical trial NCT07257042?
This trial is sponsored by Colgate Palmolive, which has 51 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07257042's enrollment target sits among peer trials
80 1755th of 2000 higher than 233 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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