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NCT06182267 · ClinicalTrials.gov registry record · Phase 1
Maximal Use Study to Determine the Pharmacokinetics of L-arginine After Exaggerated Oral Use of COL101
A Phase 1 study, sponsored by Colgate Palmolive.
- Completed
- Registry status
- Phase 1
- Development phase
- 29
- Enrollment target
NCT06182267: Completed Phase 1 study, sponsored by Colgate Palmolive.
NCT06182267 is a Phase 1 study that has completed, run by Colgate Palmolive. The registered enrollment target is 29 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (52% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06182267, a Phase 1 study, has completed, sponsored by Colgate Palmolive.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 29 participants
- Enrollment target
Study Summary
Pharmacokinetic (PK) study of L-arginine after exaggerated oral use of the novel dentifrice product COL101 after repeated daily applications in healthy adult subjects.
Primary Outcome
Measurement of arginine in blood after oral brushing
Interventions
- DRUG L Arginine
- DRUG Sodium Fluoride
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 29 participants |
| Start Date | 2023-11-27 |
| Est. Completion | 2023-12-22 |
| Phase | Phase 1 |
What the finished NCT06182267 record still lists
NCT06182267 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 29 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (52% lower).
The record links to 0 conditions, and to 2 interventions - of which L Arginine is the first listed.
NCT06182267 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT06182267 about?
NCT06182267 is a clinical study titled "Maximal Use Study to Determine the Pharmacokinetics of L-arginine After Exaggerated Oral Use of COL101". Pharmacokinetic (PK) study of L-arginine after exaggerated oral use of the novel dentifrice product COL101 after repeated daily applications in healthy adult subjects.
What is the current status of trial NCT06182267?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 29 participants. The study started on 2023-11-27. Estimated completion is 2023-12-22.
What interventions are being tested in trial NCT06182267?
The interventions under investigation include: L Arginine (DRUG), Sodium Fluoride (DRUG).
Who is sponsoring clinical trial NCT06182267?
This trial is sponsored by Colgate Palmolive, which has 51 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06182267's enrollment target sits among peer trials
29 1440th of 2000 higher than 554 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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